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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to type IV hypersensitivity reaction
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Accession:MP:0005617 term browser browse the term
Definition:greater likelihood of developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact
Comment:Examples of this include: granulomatous diseases: tuberculosis, and sarcoidosis contact dermatitis: elicited by poison ivy, detergents, clothing, etc.
Synonyms:exact_synonym: decreased resistance to cell-mediated hypersensitivity;   decreased resistance to delayed type hypersensitivity;   decreased resistance to type IV hypersensitivity reaction;   increased susceptibility to cell-mediated hypersensitivity;   increased susceptibility to delayed type hypersensitivity



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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal hypersensitivity reaction 4
          abnormal type IV hypersensitivity reaction 0
            increased susceptibility to type IV hypersensitivity reaction 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal inflammatory response 229
          increased inflammatory response 221
            increased acute inflammation 4
              increased susceptibility to type IV hypersensitivity reaction 0
paths to the root