Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to type I hypersensitivity reaction
go back to main search page
Accession:MP:0005596 term browser browse the term
Definition:greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks
Comment:Examples of this type of hypersensitivity include hay fever, asthma, and anaphylaxis.
Synonyms:exact_synonym: decreased resistance to anaphylactic shock;   decreased resistance to anaphylaxis;   decreased resistance to immediate type hypersensitivity;   decreased resistance to type I hypersensitivity reaction;   increased susceptibility to allergic response;   increased susceptibility to anaphylactic shock;   increased susceptibility to anaphylaxis;   increased susceptibility to immediate type hypersensitivity
 alt_id: MP:0001878



show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    immune system phenotype 499
      abnormal immune system physiology 381
        abnormal adaptive immunity 60
          abnormal type I hypersensitivity reaction 0
            increased susceptibility to type I hypersensitivity reaction 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    immune system phenotype 499
      abnormal immune system physiology 381
        abnormal inflammatory response 229
          abnormal acute inflammation 5
            abnormal type I hypersensitivity reaction 0
              increased susceptibility to type I hypersensitivity reaction 0
paths to the root