Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal circulating thyroxine level
go back to main search page
Accession:MP:0005475 term browser browse the term
Definition:anomaly in the blood concentration of the major hormone derived from the thyroid gland that normally affects cellular metabolism
Synonyms:exact_synonym: abnormal circulating level of T4;   abnormal circulating level of thryoxin;   abnormal circulating level of thryoxine



show annotations for term's descendants           Sort by:
decreased circulating thyroxine level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 IAGP MGI PMID:22037765 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Ap1g1 adaptor protein complex AP-1, gamma 1 subunit IAGP MGI PMID:27090238 NCBI chr 8:110,505,215...110,590,842
Ensembl chr 8:110,505,186...110,590,836
JBrowse link
G B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 IAGP MGI PMID:9013935 NCBI chr 4:40,804,602...40,855,711
Ensembl chr 4:40,804,602...40,854,005
JBrowse link
G Braf Braf transforming gene IAGP MGI PMID:21512141 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Cand2 cullin associated and neddylation dissociated 2 (putative) IEA MGI NCBI chr 6:115,751,518...115,782,516
Ensembl chr 6:115,751,499...115,782,518
JBrowse link
G Crym crystallin, mu IAGP MGI PMID:17264173 NCBI chr 7:119,785,603...119,801,212
Ensembl chr 7:119,785,603...119,801,334
JBrowse link
G Ctsk cathepsin K IAGP MGI PMID:12782676 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Ctsl cathepsin L IAGP MGI PMID:12782676 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEA MGI NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
JBrowse link
G Dio3 deiodinase, iodothyronine type III IAGP MGI PMID:16410833 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Duox2 dual oxidase 2 IAGP MGI PMID:17440044 NCBI chr 2:122,109,727...122,129,221
Ensembl chr 2:122,109,728...122,128,930
JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,088
Ensembl chr 2:122,129,381...122,133,366
JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase) IAGP MGI PMID:19349303 NCBI chr13:97,060,852...97,087,422
Ensembl chr13:97,061,197...97,087,414
JBrowse link
G Gdap2 ganglioside-induced differentiation-associated-protein 2 IEA MGI NCBI chr 3:100,069,843...100,117,909
Ensembl chr 3:100,069,697...100,114,297
JBrowse link
G Ghr growth hormone receptor IAGP MGI PMID:11395925 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
JBrowse link
G Gna11 guanine nucleotide binding protein, alpha 11 IAGP MGI PMID:17694176 NCBI chr10:81,364,558...81,380,996
Ensembl chr10:81,364,558...81,381,024
JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide IAGP MGI PMID:17694176 NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:24374551 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Itprid2 ITPR interacting domain containing 2 IAGP MGI PMID:19156225 NCBI chr 2:79,419,207...79,503,310
Ensembl chr 2:79,465,696...79,503,310
JBrowse link
G Lepr leptin receptor IAGP MGI PMID:22522563 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Lhx3 LIM homeobox protein 3 IAGP MGI PMID:21149718 NCBI chr 2:26,090,224...26,098,261
Ensembl chr 2:26,090,224...26,098,301
JBrowse link
G Med1 mediator complex subunit 1 IAGP MGI PMID:10882104 NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEA MGI NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 IAGP MGI PMID:19052228 PMID:21239618 NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal IAGP MGI PMID:22522563 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
G Oat ornithine aminotransferase IEA MGI NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Pax8 paired box 8 IAGP MGI PMID:9590297 PMID:14981357 PMID:25127920 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
JBrowse link
G Pdyn prodynorphin IAGP MGI PMID:17456788 NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764
JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 IAGP MGI PMID:36719796 NCBI chr 2:24,865,235...24,944,084
Ensembl chr 2:24,866,045...24,944,069
JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:15070780 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IAGP MGI PMID:15520383 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460
JBrowse link
G Runx2 runt related transcription factor 2 IAGP MGI PMID:20375239 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sirt1 sirtuin 1 IAGP MGI PMID:18335035 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 IAGP MGI PMID:16709608 PMID:17318265 NCBI chr  X:102,741,020...102,865,594
Ensembl chr  X:102,741,020...102,865,589
JBrowse link
G Slc26a7 solute carrier family 26, member 7 IAGP MGI PMID:30333321 NCBI chr 4:14,502,430...14,621,946
Ensembl chr 4:14,502,430...14,621,805
JBrowse link
G Slc30a10 solute carrier family 30, member 10 IAGP MGI PMID:28461334 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959
JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 IAGP MGI PMID:28706256 NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:19052228 NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317
Ensembl chr13:3,236,206...3,239,317
JBrowse link
G Tg thyroglobulin IAGP MGI PMID:3803305 NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570
JBrowse link
G Thra thyroid hormone receptor alpha IAGP MGI PMID:11159823 PMID:11726557 PMID:11731613 PMID:12576486 PMID:17327419 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832
JBrowse link
G Thrb thyroid hormone receptor beta IAGP MGI PMID:8670802 PMID:11726557 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Tpst2 protein-tyrosine sulfotransferase 2 IAGP MGI PMID:7964294 NCBI chr 5:112,424,548...112,463,222
Ensembl chr 5:112,424,557...112,463,227
JBrowse link
G Trh thyrotropin releasing hormone IAGP MGI PMID:10628753 NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631
JBrowse link
G Trhr thyrotropin releasing hormone receptor IAGP MGI PMID:17666589 PMID:25490146 NCBI chr15:44,059,314...44,099,308
Ensembl chr15:44,059,531...44,099,308
JBrowse link
G Tshr thyroid stimulating hormone receptor IAGP MGI PMID:7209519 PMID:12432094 NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
JBrowse link
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) IAGP MGI PMID:12569166 NCBI chr 8:84,016,977...84,025,085
Ensembl chr 8:84,016,981...84,025,081
JBrowse link
G Vgf VGF nerve growth factor inducible IAGP MGI PMID:10433265 NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205
JBrowse link
increased circulating thyroxine level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrp agouti related neuropeptide IAGP MGI PMID:16330327 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025
JBrowse link
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 IEA MGI NCBI chr 3:107,570,436...107,603,876
Ensembl chr 3:107,570,434...107,603,876
JBrowse link
G Braf Braf transforming gene IAGP MGI PMID:21220306 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 IEA MGI NCBI chr 8:3,637,237...3,659,075
Ensembl chr 8:3,637,293...3,659,075
JBrowse link
G Ddx42 DEAD box helicase 42 IEA MGI NCBI chr11:106,107,715...106,139,966
Ensembl chr11:106,107,752...106,139,965
JBrowse link
G Dhx33 DEAH-box helicase 33 IEA MGI NCBI chr11:70,874,917...70,895,258
Ensembl chr11:70,874,917...70,895,263
JBrowse link
G Dio1 deiodinase, iodothyronine, type I IAGP MGI PMID:16223863 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Dio2 deiodinase, iodothyronine, type II IAGP MGI PMID:11731615 PMID:23524969 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
G Dio3 deiodinase, iodothyronine type III IAGP MGI PMID:25004090 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial IAGP MGI PMID:12960027 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:15699348 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:24265449 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Mlec malectin IEA MGI NCBI chr 5:115,281,040...115,296,235
Ensembl chr 5:115,281,040...115,296,238
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 IAGP MGI PMID:12576486 NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
JBrowse link
G Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha IAGP MGI PMID:24512487 NCBI chr11:109,539,849...109,560,489
Ensembl chr11:109,540,231...109,560,482
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:21952241 PMID:24512487 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Skida1 SKI/DACH domain containing 1 IEA MGI NCBI chr 2:18,048,510...18,053,627
Ensembl chr 2:18,045,487...18,053,862
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:25004090 NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317
Ensembl chr13:3,236,206...3,239,317
JBrowse link
G Thra thyroid hormone receptor alpha IAGP MGI PMID:9927422 PMID:12576486 PMID:12869545 PMID:15601836 PMID:21914860 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832
JBrowse link
G Thrb thyroid hormone receptor beta IAGP MGI PMID:8670802 PMID:9927422 PMID:11069286 PMID:11159823 PMID:11496110 More... NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Zmynd11 zinc finger, MYND domain containing 11 IEA MGI NCBI chr13:9,734,872...9,816,050
Ensembl chr13:9,734,869...9,815,366
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    homeostasis/metabolism phenotype 7711
      abnormal homeostasis 6868
        abnormal hormone level 1290
          abnormal circulating hormone level 1156
            abnormal circulating thyroxine level 65
              decreased circulating thyroxine level 47
              increased circulating thyroxine level 24
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    homeostasis/metabolism phenotype 7711
      abnormal homeostasis 6868
        abnormal hormone level 1290
          abnormal thyroid hormone level 85
            abnormal thyroxine level 76
              abnormal circulating thyroxine level 65
                decreased circulating thyroxine level 47
                increased circulating thyroxine level 24
paths to the root