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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating aspartate transaminase level
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Accession:MP:0005343 term browser browse the term
Definition:greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction
Synonyms:exact_synonym: elevated AST level;   elevated aspartate transaminase level;   elevated circulating AAT level;   elevated circulating ASAT level;   elevated circulating SGOT level;   elevated circulating aspartate transaminase level;   elevated circulating serum glutamic oxaloacetic transaminase level;   increased AST level;   increased circulating AAT level;   increased circulating ASAT level;   increased circulating SGOT level;   increased circulating aspartate aminotransferase level;   increased circulating serum glutamic oxaloacetic transaminase level


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increased circulating aspartate transaminase level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor sexual_dimorphism IMP females compared to Hsd:SD females RGD PMID:23859880 RGD:13204753 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrem2Sage aryl hydrocarbon receptor; ZFN induced mutant2, Sage sexual_dimorphism IMP females compared to Hsd:SD females RGD PMID:23859880 RGD:13204753
G Atp7b ATPase copper transporting beta IAGP compared to LEA/Hok RGD PMID:30733544 RGD:25823141 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis IAGP compared to LEA/Hok RGD PMID:30733544 RGD:25823141
G Lamp2 lysosomal-associated membrane protein 2 IMP in hemizygote mutant male (LAMP2y/-) RGD PMID:28124283 RGD:13703118 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Lamp2em1 lysosomal-associated membrane protein 2; TALEN induced mutant1 IMP RGD PMID:28124283 RGD:13703118
G Lepr leptin receptor IMP RGD PMID:27225180 RGD:12910507 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Leprem3 leptin receptor; TALEN induced mutant 3 IMP RGD PMID:27225180 RGD:12910507
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5369
    homeostasis/metabolism phenotype 1392
      abnormal homeostasis 1298
        abnormal enzyme/coenzyme level 81
          abnormal circulating enzyme level 60
            abnormal circulating aspartate transaminase level 23
              increased circulating aspartate transaminase level 13
Path 2
Term Annotations click to browse term
  mammalian phenotype 5369
    homeostasis/metabolism phenotype 1392
      abnormal homeostasis 1298
        abnormal protein level 128
          abnormal circulating protein level 104
            abnormal circulating enzyme level 60
              abnormal circulating aspartate transaminase level 23
                increased circulating aspartate transaminase level 13
paths to the root