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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:insulin resistance
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Accession:MP:0005331 term browser browse the term
Definition:diminished effectiveness of insulin in lowering plasma glucose levels
Synonyms:xref: EFO:0002614

show annotations for term's descendants           Sort by:
insulin resistance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:27465994 RGD:12911217 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:27465994 RGD:12911217
G Pparg peroxisome proliferator-activated receptor gamma induces IAGP compared to wild type rats RGD PMID:27381370 RGD:127285618 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargm1Kyo peroxisome proliferator-activated receptor gamma; ENU induced mutant 1, Kyo induces IAGP compared to wild type rats RGD PMID:27381370 RGD:127285618
G Tbc1d4 TBC1 domain family, member 4 IMP RGD PMID:32053588 PMID:31034517 RGD:38596323, RGD:38596332 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
JBrowse link
G Tbc1d4em1 TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1, IMP RGD PMID:32053588 PMID:31034517 RGD:38596323, RGD:38596332

Term paths to the root
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  mammalian phenotype 5402
    homeostasis/metabolism phenotype 1418
      abnormal homeostasis 1319
        abnormal glucose homeostasis 355
          insulin resistance 32
paths to the root