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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal mesangial cell morphology
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Accession:MP:0005327 term browser browse the term
Definition:any structural anomaly of the modified smooth muscle cells that are interposed between endothelial cells and the basement membrane in the central or stalk region of the capillary tuft of the renal glomerulus, which regulate blood flow by their contractile activity, and secrete extracellular matrix, prostaglandins, and cytokines; mesangial cells also have phagocytic activity, removing proteins and other molecules trapped in the glomerular basement membrane or filtration barrier
Synonyms:exact_synonym: abnormal deep cell;   abnormal intercapillary cell;   abnormal intraglomerular mesangial cell



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abnormal mesangial cell morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Glom10 Glomerulus QTL 10 IDA RGD PMID:16720678 RGD:1581737 NCBI chr11:1...35,331,169 JBrowse link
Q Glom11 Glomerulus QTL 11 IDA RGD PMID:16720678 RGD:1581737
Q Glom12 Glomerulus QTL 12 IDA RGD PMID:16720678 RGD:1581737 NCBI chr 5:33,215,665...78,215,665 JBrowse link
Q Glom13 Glomerulus QTL 13 IDA RGD PMID:16720678 RGD:1581737
Q Glom14 Glomerulus QTL 14 IDA RGD PMID:16720678 RGD:1581737 NCBI chr15:34,054,139...79,054,139 JBrowse link
Q Glom9 Glomerulus QTL 9 IDA RGD PMID:16720678 RGD:1581737 NCBI chr 2:92,337,601...137,337,601 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    cellular phenotype 187
      abnormal cell morphology 47
        abnormal mesangial cell morphology 6
          decreased mesangial cell number + 0
          increased mesangial cell number 0
          mesangial cell interposition 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    renal/urinary system phenotype 649
      abnormal renal/urinary system morphology 279
        abnormal kidney morphology 272
          abnormal kidney cortex morphology 113
            abnormal renal corpuscle morphology 108
              abnormal renal glomerulus morphology 106
                abnormal glomerular mesangium morphology 13
                  abnormal mesangial cell morphology 6
                    decreased mesangial cell number + 0
                    increased mesangial cell number 0
                    mesangial cell interposition 0
paths to the root