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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:impaired glucose tolerance
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Accession:MP:0005293 term browser browse the term
Definition:less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals
Synonyms:exact_synonym: glucose intolerance;   poor glucose tolerance;   reduced glucose tolerance



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impaired glucose tolerance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IAGP compared to wild type RGD PMID:30616503 RGD:150573710 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Abcc8em1Cgen ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen IAGP compared to wild type RGD PMID:30616503 RGD:150573710
G Ldlr low density lipoprotein receptor IMP RGD PMID:28469073 RGD:12910100 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrem1Sage low density lipoprotein receptor; ZFN induced mutant 1, Sage IMP RGD PMID:28469073 RGD:12910100
G Lepr leptin receptor IMP compared to SS/JrHsdMcwi RGD PMID:27225180 PMID:27465994 RGD:12910507, RGD:12911217 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:27465994 RGD:12911217
G Leprem3 leptin receptor; TALEN induced mutant 3 IMP RGD PMID:27225180 RGD:12910507
G Pparg peroxisome proliferator-activated receptor gamma IAGP compared to wild type rats RGD PMID:27381370 RGD:127285618 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargm1Kyo peroxisome proliferator-activated receptor gamma; ENU induced mutant 1, Kyo IAGP compared to wild type rats RGD PMID:27381370 RGD:127285618
G Tbc1d4 TBC1 domain family, member 4 IMP RGD PMID:32053588 PMID:31034517 RGD:38596323, RGD:38596332 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
JBrowse link
G Tbc1d4em1 TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1, IMP RGD PMID:32053588 PMID:31034517 RGD:38596323, RGD:38596332
G Wfs1 wolframin ER transmembrane glycoprotein onset IMP RGD PMID:28860598 RGD:149735331 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
JBrowse link
G Wfs1em1Ptsn wolframin ER transmembrane glycoprotein; ZFN induced mutant 1 onset IMP RGD PMID:28860598 RGD:149735331
G Wfs1em2Ptsn wolframin ER transmembrane glycoprotein; ZFN induced mutant 2 onset IMP RGD PMID:28860598 RGD:149735331
G Wfs1em3Ptsn wolframin ER transmembrane glycoprotein; ZFN induced mutant 3 onset IMP RGD PMID:28860598 RGD:149735331

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  mammalian phenotype 5401
    homeostasis/metabolism phenotype 1415
      abnormal homeostasis 1316
        abnormal glucose homeostasis 352
          abnormal glucose tolerance 113
            impaired glucose tolerance 99
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