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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased Sertoli cell number
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Accession:MP:0005250 term browser browse the term
Definition:decreased number of the supporting cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis
Synonyms:exact_synonym: reduced Sertoli cell number
 narrow_synonym: Sertoli cell hypoplasia



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decreased Sertoli cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wwox WW domain-containing oxidoreductase IAGP compared to wild type and heterozygotes RGD PMID:18676360 RGD:150429974 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
G Wwoxlde WW domain-containing oxidoreductase; lde mutant IAGP compared to wild type and heterozygotes RGD PMID:18676360 RGD:150429974

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5364
    reproductive system phenotype 128
      abnormal reproductive system morphology 97
        abnormal sex gland morphology 67
          abnormal male reproductive gland morphology 58
            abnormal testis morphology 46
              abnormal seminiferous tubule morphology 12
                abnormal seminiferous tubule epithelium morphology 4
                  abnormal Sertoli cell morphology 4
                    decreased Sertoli cell number 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5364
    reproductive system phenotype 128
      abnormal reproductive system morphology 97
        abnormal male reproductive system morphology 66
          abnormal male genitalia morphology 66
            abnormal internal male genitalia morphology 58
              abnormal testis morphology 46
                abnormal seminiferous tubule morphology 12
                  abnormal seminiferous tubule epithelium morphology 4
                    abnormal Sertoli cell morphology 4
                      decreased Sertoli cell number 3
paths to the root