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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased circulating cholesterol level
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Accession:MP:0005179 term browser browse the term
Definition:less than the normal amount in the blood of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Synonyms:exact_synonym: decreased total circulating cholesterol level;   hypocholesterolaemia;   hypocholesterolemia;   low total circulating cholesterol level;   reduced circulating cholesterol level
 narrow_synonym: decreased total plasma cholesterol level;   decreased total serum cholesterol level;   low total plasma cholesterol level;   low total serum cholesterol level
 alt_id: MP:0002616


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decreased circulating cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfb complement factor B IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfbem1Tja complement factor B, ZFN induced mutant 1, Tja IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403
G Htr7 5-hydroxytryptamine receptor 7 IMP in male RGD PMID:31125290 RGD:14696717 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Htr7em1Msu 5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu IMP in male RGD PMID:31125290 RGD:14696717
G Zbtb16 zinc finger and BTB domain containing 16 IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
G Zbtb16em1Ipcv zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv IMP compared to wild type SHR/OlaIpcv; RGD PMID:28396530 RGD:150340623
decreased circulating HDL cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IMP RGD PMID:30796231 RGD:150521536 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Atp7b ATPase copper transporting beta IAGP RGD PMID:17303181 RGD:2292672 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis IAGP RGD PMID:17303181 RGD:2292672
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5374
    homeostasis/metabolism phenotype 1396
      abnormal homeostasis 1299
        abnormal blood homeostasis 743
          abnormal circulating lipid level 296
            abnormal circulating cholesterol level 160
              decreased circulating cholesterol level 39
                decreased circulating HDL cholesterol level 13
                decreased circulating LDL cholesterol level 1
                decreased circulating VLDL cholesterol level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5374
    homeostasis/metabolism phenotype 1396
      abnormal homeostasis 1299
        abnormal lipid homeostasis 350
          abnormal lipid level 345
            abnormal sterol level 185
              abnormal cholesterol level 184
                abnormal circulating cholesterol level 160
                  decreased circulating cholesterol level 39
                    decreased circulating HDL cholesterol level 13
                    decreased circulating LDL cholesterol level 1
                    decreased circulating VLDL cholesterol level 0
paths to the root