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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal blood-brain barrier function
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Accession:MP:0005167 term browser browse the term
Definition:anomaly in the function of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood
Synonyms:exact_synonym: abnormal BBB function


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abnormal blood-brain barrier function term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1aem2Sage ATP binding cassette subfamily B member 1A; ZFN induced mutant 2, Sage IMP RGD PMID:22049154 RGD:8657330
G Abcc2 ATP binding cassette subfamily C member 2 IAGP RGD PMID:12663688 RGD:704399 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Crh corticotropin releasing hormone IDA RGD PMID:12663088 RGD:704425 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    nervous system phenotype 362
      abnormal nervous system physiology 206
        abnormal blood-brain barrier function 6
          enhanced blood-brain barrier function 0
          impaired blood-brain barrier function 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    cardiovascular system phenotype 1361
      abnormal cardiovascular system physiology 1137
        abnormal vasculature physiology 69
          abnormal blood vessel physiology 69
            abnormal blood-brain barrier function 6
              enhanced blood-brain barrier function 0
              impaired blood-brain barrier function 0
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