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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T cell proliferation
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Accession:MP:0005094 term browser browse the term
Definition:anomaly in the ability of a naive T cell population to undergo rapid expansion by cell division in response to stimuli


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decreased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 Cd247 molecule IMP compared to wild-type RGD PMID:24343121 RGD:13442481 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263 		JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:24343121 RGD:13442481
increased T cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Themis thymocyte selection associated IAGP DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:16,433,906...16,623,889
Ensembl chr 1:16,432,631...16,664,329 		JBrowse link
G Themism1Adej thymocyte selection associated; mutant1, Adej IAGP compared to BN RGD PMID:22275874 RGD:38599149
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    cellular phenotype 184
      abnormal cell physiology 143
        abnormal cell proliferation 25
          abnormal T cell proliferation 10
            decreased T cell proliferation 4
            increased T cell proliferation 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal adaptive immunity 60
          abnormal leukocyte physiology 56
            abnormal lymphocyte physiology 49
              abnormal T cell physiology 14
                abnormal T cell activation 10
                  abnormal T cell proliferation 10
                    decreased T cell proliferation 4
                    increased T cell proliferation 6
paths to the root