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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal eosinophil morphology
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Accession:MP:0005061 term browser browse the term
Definition:any structural anomaly of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin and is involved in clearance of parasitic infections and in allergic reactions
Synonyms:exact_synonym: abnormal eosinocyte morphology;   abnormal eosinophilic leucocyte morphology;   abnormal eosinophilic leukocyte morphology;   eosinophil structural abnormalities
 broad_synonym: abnormal polymorphonuclear leucocyte morphology;   abnormal polymorphonuclear leukocyte morphology


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decreased eosinophil cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422 		JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
G Fh fumarate hydratase IMP RGD PMID:27556703 RGD:13792708 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627 		JBrowse link
G Fhem1 fumarate hydratase; TALEN induced mutant 1 IMP RGD PMID:27556703 RGD:13792708
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:23799078 RGD:13462048 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239 		JBrowse link
G Lrrk2em1Sage leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:23799078 RGD:13462048
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5432
    hematopoietic system phenotype 267
      abnormal hematopoietic system morphology/development 247
        abnormal bone marrow cell morphology/development 29
          abnormal myeloblast morphology/development 19
            abnormal eosinophil morphology 16
              abnormal eosinophil cell number + 16
              abnormal eosinophil differentiation 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5432
    hematopoietic system phenotype 267
      abnormal hematopoietic system morphology/development 247
        abnormal hematopoietic cell morphology 182
          abnormal leukocyte morphology 150
            abnormal myeloid leukocyte morphology 68
              abnormal granulocyte morphology 41
                abnormal eosinophil morphology 16
                  abnormal eosinophil cell number + 16
                  abnormal eosinophil differentiation 0
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