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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased regulatory T cell number
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Accession:MP:0004974 term browser browse the term
Definition:reduced number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity
Synonyms:exact_synonym: decreased Treg cell number;   decreased suppressor T cell number;   reduced Treg cell number;   reduced regulatory T cell number



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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    hematopoietic system phenotype 0
      abnormal hematopoietic system morphology/development 0
        abnormal hematopoietic cell morphology 0
          abnormal leukocyte morphology 0
            abnormal leukocyte cell number 0
              decreased leukocyte cell number 0
                decreased lymphocyte cell number 0
                  decreased T cell number 0
                    decreased regulatory T cell number 0
                      absent regulatory T cells 0
                      decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system cell morphology 0
          abnormal leukocyte morphology 0
            abnormal mononuclear cell morphology 0
              abnormal lymphocyte morphology 0
                abnormal T cell morphology 0
                  abnormal regulatory T cell morphology 0
                    abnormal regulatory T cell number 0
                      decreased regulatory T cell number 0
                        absent regulatory T cells 0
                        decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 0
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