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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal regulatory T cell number
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Accession:MP:0004972 term browser browse the term
Definition:deviation from the average count of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity
Synonyms:exact_synonym: abnormal Treg cell number;   abnormal suppressor T cell number


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abnormal regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta IAGP MGI PMID:23544080 NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:24164480 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:26099023 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Il10ra interleukin 10 receptor, alpha IAGP MGI PMID:22711892 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 IAGP MGI PMID:26132627 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Nckap1l NCK associated protein 1 like IAGP MGI PMID:19015308 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 IAGP MGI PMID:26099023 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898 		JBrowse link
G Sell selectin, lymphocyte IAGP MGI PMID:17182566 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Sgpl1 sphingosine phosphate lyase 1 IAGP MGI PMID:23544080 NCBI chr10:60,934,421...60,983,463
Ensembl chr10:60,934,421...60,983,482 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:26099023 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:24164480 NCBI chr 1:36,800,879...36,821,902
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Colgalt2 collagen beta(1-O)galactosyltransferase 2 IAGP MGI PMID:30355948 NCBI chr 1:152,275,485...152,386,446
Ensembl chr 1:152,275,581...152,386,446 		JBrowse link
absent regulatory T cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd10 COMM domain containing 10 IAGP MGI PMID:29127143 NCBI chr18:47,091,886...47,221,062
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:16275384 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 IAGP MGI PMID:16940043 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Satb1 special AT-rich sequence binding protein 1 IAGP MGI PMID:29127143 NCBI chr17:52,043,215...52,140,318
Ensembl chr17:52,043,215...52,140,318 		JBrowse link
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd38 CD38 antigen IEA MGI NCBI chr 5:44,026,151...44,069,716
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Elmo1 engulfment and cell motility 1 IEA MGI NCBI chr13:20,274,677...20,792,523
Ensembl chr13:20,274,766...20,792,523 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:12612578 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Gmnn geminin IAGP MGI PMID:20107189 NCBI chr13:24,935,828...24,954,222
Ensembl chr13:24,935,828...24,945,906 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 IAGP MGI PMID:16709807 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:33658989 NCBI chr 8:23,149,221...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Itk IL2 inducible T cell kinase IEA MGI NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 IAGP MGI PMID:26132627 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A IAGP MGI PMID:19679885 NCBI chr  X:163,202,776...163,216,912
Ensembl chr  X:163,202,783...163,216,912 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA MGI NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:16493008 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IAGP MGI PMID:16493008 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,879...36,821,902
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,366
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
decreased regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) IAGP MGI PMID:21300913 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a IAGP MGI PMID:28085150 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IAGP MGI PMID:28085150 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d IAGP MGI PMID:28085150 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:19260764 NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 IAGP MGI PMID:23793062 NCBI chr 8:106,412,642...106,424,827
Ensembl chr 8:106,412,906...106,424,819 		JBrowse link
G Cd1d1 CD1d1 antigen IAGP MGI PMID:16339525 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748 		JBrowse link
G Cd27 CD27 antigen IAGP MGI PMID:23547099 NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973 		JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:15467837 PMID:23065717 PMID:23281398 PMID:23793062 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd40lg CD40 ligand IAGP MGI PMID:15467837 NCBI chr  X:56,257,503...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd70 CD70 antigen IAGP MGI PMID:23547099 NCBI chr17:57,452,997...57,456,777
Ensembl chr17:57,452,997...57,456,777 		JBrowse link
G Cd80 CD80 antigen IAGP MGI PMID:16886063 PMID:23793062 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697 		JBrowse link
G Cd86 CD86 antigen IAGP MGI PMID:15467837 PMID:16886063 PMID:23793062 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:18725525 PMID:18725527 NCBI chr12:104,653,999...104,718,227
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Drosha drosha, ribonuclease type III IAGP MGI PMID:18725527 NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377 		JBrowse link
G E2f1 E2F transcription factor 1 IAGP MGI PMID:15470032 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Fads1 fatty acid desaturase 1 IAGP MGI PMID:22534642 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:18209052 PMID:20072126 PMID:21460251 PMID:23281398 PMID:27410049 More... NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Fyn Fyn proto-oncogene IAGP MGI PMID:19668367 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Gpr15 G protein-coupled receptor 15 IAGP MGI PMID:23661644 NCBI chr16:58,537,006...58,539,235
Ensembl chr16:58,537,796...58,539,433 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:18354198 PMID:23065717 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 IAGP MGI PMID:23712430 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G Ier3 immediate early response 3 IAGP MGI PMID:19923449 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:14499113 NCBI chr 8:23,149,221...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma IEA MGI NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Ikzf4 IKAROS family zinc finger 4 IAGP MGI PMID:31296356 NCBI chr10:128,466,708...128,505,668
Ensembl chr10:128,466,712...128,505,227 		JBrowse link
G Il15 interleukin 15 IAGP MGI PMID:23805138 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IAGP MGI PMID:16227983 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IAGP MGI PMID:12196288 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain IAGP MGI PMID:19528538 PMID:23109710 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
G Itgav integrin alpha V IAGP MGI PMID:17895374 NCBI chr 2:83,551,625...83,637,261
Ensembl chr 2:83,554,741...83,637,260 		JBrowse link
G Lat linker for activation of T cells IAGP MGI PMID:18209052 PMID:19380807 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 IAGP MGI PMID:18282810 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:28533230 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IAGP MGI PMID:17060023 NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298 		JBrowse link
G Marchf1 membrane associated ring-CH-type finger 1 IAGP MGI PMID:23712430 NCBI chr 8:66,070,550...66,925,761
Ensembl chr 8:66,070,552...66,924,289 		JBrowse link
G Mir125a microRNA 125a IAGP MGI PMID:25963922 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141 		JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:19234151 PMID:26163372 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Myct1 myc target 1 IAGP MGI PMID:33658356 NCBI chr10:5,543,728...5,556,789
Ensembl chr10:5,543,775...5,556,904 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEA MGI NCBI chr 1:152,675,904...152,712,741
Ensembl chr 1:152,675,945...152,712,742 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IAGP MGI PMID:19060899 PMID:24652767 NCBI chr 3:135,290,416...135,397,728
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:21333553 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IAGP MGI PMID:21468021 NCBI chr 2:56,996,845...57,014,018
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 IAGP MGI PMID:28294127 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519 		JBrowse link
G Orai2 ORAI calcium release-activated calcium modulator 2 IAGP MGI PMID:28294127 NCBI chr 5:136,176,310...136,201,418
Ensembl chr 5:136,176,313...136,199,567 		JBrowse link
G Otud5 OTU domain containing 5 IAGP MGI PMID:25470037 NCBI chr  X:7,705,852...7,742,865
Ensembl chr  X:7,707,603...7,742,865 		JBrowse link
G Pclaf PCNA clamp associated factor IEA MGI NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing IAGP MGI PMID:28533230 NCBI chr 1:65,225,796...65,317,855
Ensembl chr 1:65,225,842...65,317,854 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma IAGP MGI PMID:27313209 NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454 		JBrowse link
G Plcg1 phospholipase C, gamma 1 IAGP MGI PMID:20123962 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680 		JBrowse link
G Rwdd1 RWD domain containing 1 IEA MGI NCBI chr10:33,872,551...33,895,612
Ensembl chr10:33,872,551...33,895,620 		JBrowse link
G Septin9 septin 9 IAGP MGI PMID:23644740 NCBI chr11:117,090,487...117,253,151
Ensembl chr11:117,090,487...117,253,151 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stim1 stromal interaction molecule 1 IAGP MGI PMID:18327260 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526 		JBrowse link
G Stim2 stromal interaction molecule 2 IAGP MGI PMID:18327260 NCBI chr 5:54,155,865...54,278,399
Ensembl chr 5:54,155,841...54,278,399 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 IAGP MGI PMID:22561606 NCBI chr10:130,158,696...130,199,338
Ensembl chr10:130,158,739...130,199,980 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II IAGP MGI PMID:23569233 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Thbs1 thrombospondin 1 IAGP MGI PMID:19700744 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Themis thymocyte selection associated IAGP MGI PMID:19597497 PMID:19597498 NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:19668367 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 IAGP MGI PMID:26195727 NCBI chr 1:192,857,812...192,883,854
Ensembl chr 1:192,857,761...192,884,011 		JBrowse link
G Trim56 tripartite motif-containing 56 IEA MGI NCBI chr 5:137,140,140...137,145,313
Ensembl chr 5:137,134,498...137,145,063 		JBrowse link
G Usp17lc ubiquitin specific peptidase 17-like C IAGP MGI PMID:22984479 NCBI chr 7:103,065,903...103,068,381
Ensembl chr 7:103,064,279...103,069,087 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor IAGP MGI PMID:17959935 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
G Was Wiskott-Aldrich syndrome IAGP MGI PMID:17878299 NCBI chr  X:7,947,705...7,956,730
Ensembl chr  X:7,947,692...7,956,737 		JBrowse link
G Wasl WASP like actin nucleation promoting factor IAGP MGI PMID:17878299 NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008 		JBrowse link
G Xcl1 chemokine (C motif) ligand 1 IAGP MGI PMID:21300913 NCBI chr 1:164,759,213...164,763,091
Ensembl chr 1:164,759,213...164,763,096 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:19841086 NCBI chr 1:36,800,879...36,821,902
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zfp335 zinc finger protein 335 IAGP MGI PMID:25343476 NCBI chr 2:164,733,802...164,756,034
Ensembl chr 2:164,733,802...164,753,677 		JBrowse link
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G C9orf72 C9orf72, member of C9orf72-SMCR8 complex IAGP MGI PMID:27412785 NCBI chr 4:35,191,285...35,226,153
Ensembl chr 4:35,191,285...35,226,175 		JBrowse link
G Cd22 CD22 antigen IEA MGI NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,366
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
G Fam83h family with sequence similarity 83, member H IEA MGI NCBI chr15:75,872,941...75,886,185
Ensembl chr15:75,872,942...75,886,185 		JBrowse link
G Fgd3 FYVE, RhoGEF and PH domain containing 3 IEA MGI NCBI chr13:49,415,030...49,473,783
Ensembl chr13:49,415,030...49,473,787 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Lair1 leukocyte-associated Ig-like receptor 1 IAGP MGI PMID:22156345 NCBI chr 7:4,010,072...4,076,566
Ensembl chr 7:4,006,401...4,066,203 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 IEA MGI NCBI chr16:87,173,539...87,229,504
Ensembl chr16:87,173,539...87,229,500 		JBrowse link
G Mmp20 matrix metallopeptidase 20 (enamelysin) IEA MGI NCBI chr 9:7,628,232...7,674,969
Ensembl chr 9:7,628,232...7,674,980 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IAGP MGI PMID:28471497 NCBI chr 1:152,675,904...152,712,741
Ensembl chr 1:152,675,945...152,712,742 		JBrowse link
G Nup210 nucleoporin 210 IAGP MGI PMID:30323813 NCBI chr 6:90,990,049...91,095,920
Ensembl chr 6:90,990,050...91,093,811 		JBrowse link
G Pax5 paired box 5 IEA MGI NCBI chr 4:44,524,748...44,710,694
Ensembl chr 4:44,524,757...44,710,487 		JBrowse link
G Phf6 PHD finger protein 6 IAGP MGI PMID:31395598 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA MGI NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Siglecg sialic acid binding Ig-like lectin G IEA MGI NCBI chr 7:43,057,617...43,067,773
Ensembl chr 7:43,057,628...43,067,782 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Spred1 sprouty protein with EVH-1 domain 1, related sequence IEA MGI NCBI chr 2:116,951,552...117,012,760
Ensembl chr 2:116,951,855...117,012,760 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) IEA MGI NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,879...36,821,902
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zscan10 zinc finger and SCAN domain containing 10 IAGP MGI PMID:25111779 NCBI chr17:23,819,800...23,829,993
Ensembl chr17:23,819,830...23,829,993 		JBrowse link
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 IEA MGI NCBI chr 7:24,601,762...24,626,019
Ensembl chr 7:24,602,337...24,626,019 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Il27 interleukin 27 IEA MGI NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Cttnbp2 cortactin binding protein 2 IEA MGI NCBI chr 6:18,366,470...18,515,216
Ensembl chr 6:18,366,477...18,514,842 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Pclaf PCNA clamp associated factor IEA MGI NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548 		JBrowse link
G Pepd peptidase D IEA MGI NCBI chr 7:34,611,832...34,744,133
Ensembl chr 7:34,611,804...34,744,133 		JBrowse link
increased regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:26214133 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Atg7 autophagy related 7 IAGP MGI PMID:26214133 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G B9d2 B9 protein domain 2 IAGP MGI PMID:21435587 NCBI chr 7:25,380,205...25,385,987
Ensembl chr 7:25,380,205...25,385,983 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 IAGP MGI PMID:23805138 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Bax BCL2-associated X protein IAGP MGI PMID:23805138 NCBI chr 7:45,111,119...45,116,344
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) IAGP MGI PMID:23805138 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:21844204 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Cd247 CD247 antigen IAGP MGI PMID:22945921 NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846 		JBrowse link
G Cd4 CD4 antigen IAGP MGI PMID:24115907 NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:22904299 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:21530328 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622 		JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:21844204 NCBI chr18:47,091,886...47,221,062
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IAGP MGI PMID:18845758 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Ctsl cathepsin L IAGP MGI PMID:19664906 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Dmd dystrophin, muscular dystrophy IAGP MGI PMID:19451692 NCBI chr  X:81,858,244...84,248,656
Ensembl chr  X:81,992,476...84,249,747 		JBrowse link
G Fgl2 fibrinogen-like protein 2 IAGP MGI PMID:18097026 NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372 		JBrowse link
G Foxo1 forkhead box O1 IAGP MGI PMID:23135404 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:17481928 PMID:17581588 PMID:18845758 PMID:20850013 PMID:21435587 More... NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Fyn Fyn proto-oncogene IAGP MGI PMID:19668367 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23966625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:30337470 NCBI chr 8:23,149,221...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 IAGP MGI PMID:28327619 NCBI chr 1:40,363,697...40,406,722
Ensembl chr 1:40,363,770...40,406,722 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IAGP MGI PMID:16227983 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il36g interleukin 36G IAGP MGI PMID:28327619 NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580 		JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:17581588 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itch itchy, E3 ubiquitin protein ligase IAGP MGI PMID:24135136 NCBI chr 2:154,975,401...155,068,775
Ensembl chr 2:154,975,429...155,068,775 		JBrowse link
G Itgav integrin alpha V IAGP MGI PMID:17895374 NCBI chr 2:83,551,625...83,637,261
Ensembl chr 2:83,554,741...83,637,260 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:19841240 NCBI chr 6:145,162,425...145,196,144
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lrba LPS-responsive beige-like anchor IAGP MGI PMID:27824136 NCBI chr 3:86,130,763...86,690,001
Ensembl chr 3:86,131,987...86,689,999 		JBrowse link
G Lrrc8a leucine rich repeat containing 8A VRAC subunit A IAGP MGI PMID:24752297 NCBI chr 2:30,127,781...30,153,802
Ensembl chr 2:30,127,727...30,153,802 		JBrowse link
G Mir146 microRNA 146 IAGP MGI PMID:20850013 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IAGP MGI PMID:19538929 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:17911591 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pi16 peptidase inhibitor 16 IEA MGI NCBI chr17:29,537,770...29,547,876
Ensembl chr17:29,536,654...29,549,567 		JBrowse link
G Ptgdr prostaglandin D receptor IAGP MGI PMID:28630327 NCBI chr14:45,088,692...45,096,832
Ensembl chr14:45,088,692...45,096,832 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:23619366 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 IAGP MGI PMID:21844204 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
G Rhoa ras homolog family member A IAGP MGI PMID:29398449 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133 		JBrowse link
G Setd5 SET domain containing 5 IEA MGI NCBI chr 6:113,054,326...113,130,393
Ensembl chr 6:113,054,326...113,130,396 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IAGP MGI PMID:20850013 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Spp1 secreted phosphoprotein 1 IAGP MGI PMID:19451692 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Stim1 stromal interaction molecule 1 IAGP MGI PMID:21530328 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526 		JBrowse link
G Stim2 stromal interaction molecule 2 IAGP MGI PMID:21530328 NCBI chr 5:54,155,865...54,278,399
Ensembl chr 5:54,155,841...54,278,399 		JBrowse link
G Sytl1 synaptotagmin-like 1 IAGP MGI PMID:24652767 NCBI chr 4:132,980,401...132,990,398
Ensembl chr 4:132,980,401...132,990,424 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:17481928 PMID:21435587 PMID:23569233 PMID:24056369 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II IAGP MGI PMID:23569233 PMID:24115907 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:19668367 PMID:21435587 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Trex1 three prime repair exonuclease 1 IAGP MGI PMID:25848017 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Txnip thioredoxin interacting protein IAGP MGI PMID:15723808 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16233
    hematopoietic system phenotype 5190
      abnormal hematopoietic system morphology/development 4732
        abnormal hematopoietic cell morphology 3961
          abnormal hematopoietic cell number 2848
            abnormal leukocyte cell number 2367
              abnormal lymphocyte cell number 1618
                abnormal T cell number 1033
                  abnormal regulatory T cell number 156
                    abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 50
                    decreased regulatory T cell number + 89
                    increased regulatory T cell number + 82
Path 2
Term Annotations click to browse term
  mammalian phenotype 16233
    immune system phenotype 5376
      abnormal immune system morphology 3802
        abnormal immune system cell morphology 2666
          abnormal leukocyte morphology 2645
            abnormal mononuclear cell morphology 2159
              abnormal lymphocyte morphology 1749
                abnormal T cell morphology 1125
                  abnormal T cell number 1033
                    abnormal regulatory T cell number 156
                      abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 50
                      decreased regulatory T cell number + 89
                      increased regulatory T cell number + 82
paths to the root