Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal regulatory T cell number
go back to main search page
Accession:MP:0004972 term browser browse the term
Definition:deviation from the average count of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity
Synonyms:exact_synonym: abnormal Treg cell number;   abnormal suppressor T cell number


show annotations for term's descendants           Sort by:
increased regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25776069 RGD:13442483 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Sh2b3em1Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25776069 RGD:13442483
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5372
    hematopoietic system phenotype 243
      abnormal hematopoietic system morphology/development 223
        abnormal hematopoietic cell morphology 179
          abnormal hematopoietic cell number 141
            abnormal leukocyte cell number 134
              abnormal lymphocyte cell number 92
                abnormal T cell number 62
                  abnormal regulatory T cell number 7
                    abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 3
                    decreased regulatory T cell number + 3
                    increased regulatory T cell number + 4
Path 2
Term Annotations click to browse term
  mammalian phenotype 5372
    immune system phenotype 493
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal mononuclear cell morphology 120
              abnormal lymphocyte morphology 98
                abnormal T cell morphology 68
                  abnormal T cell number 62
                    abnormal regulatory T cell number 7
                      abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 3
                      decreased regulatory T cell number + 3
                      increased regulatory T cell number + 4
paths to the root