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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal spleen weight
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Accession:MP:0004951 term browser browse the term
Definition:anomaly in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets
Synonyms:exact_synonym: abnormal splenic weight



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decreased spleen weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor sexual_dimorphism IMP females compared to Hsd:SD females RGD PMID:23859880 RGD:13204753 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrem2Sage aryl hydrocarbon receptor; ZFN induced mutant2, Sage sexual_dimorphism IMP females compared to Hsd:SD females RGD PMID:23859880 RGD:13204753
G Il15 interleukin 15 IMP RGD PMID:28395334 RGD:12910490 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il15em1Soar interleukin 15; ZFN induced mutant 1, Soar IMP RGD PMID:28395334 RGD:12910490
G Prkdc protein kinase, DNA-activated, catalytic subunit IMP RGD PMID:30485360 RGD:39938998 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prkdcem1Sage protein kinase, DNA-activated, catalytic subunit; ZFN induced mutant 1, Sage IMP RGD PMID:30485360 RGD:39938998
increased spleen weight term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP in KO rat RGD PMID:30893315 RGD:126908018 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1bem1Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc IMP RGD PMID:30893315 RGD:126908018
G Cdkn1bem4Musc cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc IMP RGD PMID:30893315 RGD:126908018
G Tmem67 transmembrane protein 67 IAGP RGD PMID:15052665 RGD:15014788 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
JBrowse link
G Tmem67wpk transmembrane protein 67; wpk mutant IAGP RGD PMID:15052665 RGD:15014788

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal spleen morphology 33
          abnormal spleen size 30
            abnormal spleen weight 18
              decreased spleen weight 9
              increased spleen weight 8
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system organ morphology 73
          abnormal spleen morphology 33
            abnormal spleen size 30
              abnormal spleen weight 18
                decreased spleen weight 9
                increased spleen weight 8
paths to the root