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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal B-1 B cell morphology
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Accession:MP:0004940 term browser browse the term
Definition:any structural anomaly of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and are enriched for self-reactivity; B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas
Synonyms:exact_synonym: abnormal B-1 B lymphocyte morphology;   abnormal B1 cell morphology


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increased B-1 B cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpp4DPPIV dipeptidylpeptidase 4; DPPIV mutant IAGP compared to DA/Ztm RGD PMID:19327106 RGD:41408336
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5428
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system cell morphology 150
          abnormal professional antigen presenting cell morphology 39
            abnormal mature B cell morphology 3
              abnormal B-1 B cell morphology 3
                abnormal B-1 B cell number + 3
                abnormal B-1a B cell morphology + 0
                abnormal B-1b B cell morphology + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5428
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal mononuclear cell morphology 125
              abnormal lymphocyte morphology 97
                abnormal B cell morphology 29
                  abnormal mature B cell morphology 3
                    abnormal B-1 B cell morphology 3
                      abnormal B-1 B cell number + 3
                      abnormal B-1a B cell morphology + 0
                      abnormal B-1b B cell morphology + 0
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