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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased susceptibility to experimental autoimmune uveoretinitis
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Accession:MP:0004821 term browser browse the term
Definition:greater likelihood that an organism will develop disease symptoms similar to human sight-threatening inflammatory eye diseases upon induction by peripheral immunization with one of several uveitogenic retinal proteins (or with peptides derived from them), or by the adoptive transfer of lymphocytes specific to these antigens
Synonyms:exact_synonym: decreased resistance to EAU;   decreased resistance to experimental autoimmune uveitis;   decreased resistance to experimental autoimmune uveoretinitis;   increased susceptibility to EAU;   increased susceptibility to experimental autoimmune uveitis


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increased susceptibility to experimental autoimmune uveoretinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Eau4 Experimental allergic uveoretinitis QTL 4 IDA induced by peptide R16 RGD PMID:18453595 RGD:2296064 NCBI chr 3:137,398,739...169,034,231 JBrowse link
Q Eau5 Experimental allergic uveoretinitis QTL 5 susceptibility IDA due to L allele RGD PMID:18453595 RGD:2296064 NCBI chr 2:202,446,871...237,938,339 JBrowse link
Q Eau7 Experimental allergic uveoretinitis QTL 7 susceptibility IDA due to L allele RGD PMID:18453595 RGD:2296064 NCBI chr10:27,957,626...34,490,668 JBrowse link
Q Eau9 Experimental allergic uveoretinitis QTL 9 susceptibility IDA due to L allele RGD PMID:18453595 RGD:2296064 NCBI chr10:65,927,233...82,565,079 JBrowse link
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  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune tolerance 116
          abnormal self tolerance 116
            autoimmune response 116
              abnormal susceptibility to autoimmune disorder 105
                increased susceptibility to autoimmune disorder 46
                  increased susceptibility to experimental autoimmune uveoretinitis 5
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