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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:abnormal somatic hypermutation frequency
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Accession:MP:0004815 term browser browse the term
Definition:any anomaly in the high frequency of programmed mutation that occurs in the gene segments encoding the variable regions of antibodies during the differentiation of individual B lymphocytes into antibody producing plasma cells
Synonyms:exact_synonym: abnormal SHM

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  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal adaptive immunity 60
          abnormal somatic hypermutation frequency 0
Path 2
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  mammalian phenotype 5402
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal blood cell morphology 99
            abnormal hemopoiesis 18
              abnormal definitive hematopoiesis 18
                abnormal leukopoiesis 18
                  abnormal lymphopoiesis 18
                    abnormal B cell differentiation 0
                      abnormal somatic hypermutation frequency 0
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