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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased susceptibility to experimental autoimmune encephalomyelitis
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Accession:MP:0004799 term browser browse the term
Definition:greater likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG)
Synonyms:exact_synonym: decreased resistance to EAE;   decreased resistance to experimental allergic encephalitis;   decreased resistance to experimental allergic encephalomyelitis;   decreased resistance to experimental autoimmune encephalomyelitis;   increased susceptibility to EAE;   increased susceptibility to experimental allergic encephalitis;   increased susceptibility to experimental allergic encephalomyelitis


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increased susceptibility to experimental autoimmune encephalomyelitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S DA DA induced IAGP compared to PAG.1AV1 RGD PMID:9692888 RGD:61068
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  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune tolerance 116
          abnormal self tolerance 116
            autoimmune response 116
              abnormal susceptibility to autoimmune disorder 105
                increased susceptibility to autoimmune disorder 46
                  increased susceptibility to experimental autoimmune encephalomyelitis 1
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