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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal platelet dense granule morphology
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Accession:MP:0004721 term browser browse the term
Definition:any structural anomaly of the electron-dense bodies occurring in blood platelets that store and secrete adenosine nucleotides and serotonin
Synonyms:exact_synonym: abnormal platelet delta granule morphology;   abnormal platelet dense body morphology;   abnormal thrombocyte dense granule morphology



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abnormal platelet dense granule morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit IAGP MGI PMID:10381507 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Ap3d1 adaptor-related protein complex 3, delta 1 subunit IAGP MGI PMID:1912584 NCBI chr10:80,542,790...80,578,137
Ensembl chr10:80,542,790...80,578,098
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex-1, subunit 5, muted IAGP MGI PMID:1912584 NCBI chr13:38,786,674...38,821,093
Ensembl chr13:38,776,818...38,819,085
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 IAGP MGI PMID:6696991 NCBI chr 5:112,490,849...112,526,290
Ensembl chr 5:112,490,949...112,526,280
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:12070017 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rab32 RAB32, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
JBrowse link
G Rab38 RAB38, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr 7:88,079,481...88,140,780
Ensembl chr 7:88,079,481...88,140,780
JBrowse link
G Wdr1 WD repeat domain 1 IAGP MGI PMID:17515402 NCBI chr 5:38,684,149...38,720,265
Ensembl chr 5:38,684,156...38,720,564
JBrowse link
abnormal platelet calcium level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin2 bridging integrator 2 IAGP MGI PMID:32750041 NCBI chr15:100,538,963...100,567,384
Ensembl chr15:100,538,958...100,567,434
JBrowse link
decreased platelet ADP level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G a nonagouti IAGP MGI PMID:6696991 NCBI chr 2:154,792,519...154,892,932
Ensembl chr 2:154,633,322...154,892,932
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit IAGP MGI PMID:6696991 PMID:9434937 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin IAGP MGI PMID:6696991 NCBI chr 2:122,580,425...122,591,407
Ensembl chr 2:122,580,423...122,591,395
JBrowse link
G Dock7 dedicator of cytokinesis 7 IAGP MGI PMID:9475748 NCBI chr 4:98,824,669...99,019,190
Ensembl chr 4:98,824,908...99,009,152
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 IAGP MGI PMID:6696991 NCBI chr19:42,743,629...42,770,013
Ensembl chr19:42,743,544...42,768,417
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 IAGP MGI PMID:6696991 NCBI chr 7:46,409,890...46,445,501
Ensembl chr 7:46,409,890...46,445,488
JBrowse link
G Hps6 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 IAGP MGI PMID:6696991 NCBI chr19:45,991,917...45,994,612
Ensembl chr19:45,991,947...45,994,612
JBrowse link
G Lyst lysosomal trafficking regulator IAGP MGI PMID:6696991 NCBI chr13:13,764,896...13,953,388
Ensembl chr13:13,764,982...13,953,388
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:12070017 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rab32 RAB32, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
JBrowse link
G Rab38 RAB38, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr 7:88,079,481...88,140,780
Ensembl chr 7:88,079,481...88,140,780
JBrowse link
decreased platelet ATP level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G a nonagouti IAGP MGI PMID:6696991 NCBI chr 2:154,792,519...154,892,932
Ensembl chr 2:154,633,322...154,892,932
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit IAGP MGI PMID:6696991 PMID:9434937 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Bloc1s4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino IAGP MGI PMID:11110696 NCBI chr 5:36,904,718...36,906,023
Ensembl chr 5:36,904,722...36,905,994
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex-1, subunit 5, muted IAGP MGI PMID:1912584 NCBI chr13:38,786,674...38,821,093
Ensembl chr13:38,776,818...38,819,085
JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin IAGP MGI PMID:6696991 NCBI chr 2:122,580,425...122,591,407
Ensembl chr 2:122,580,423...122,591,395
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 IAGP MGI PMID:6696991 NCBI chr19:42,743,629...42,770,013
Ensembl chr19:42,743,544...42,768,417
JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 IAGP MGI PMID:3408670 NCBI chr 3:20,050,109...20,089,478
Ensembl chr 3:20,050,109...20,089,479
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 IAGP MGI PMID:6696991 NCBI chr 7:46,409,890...46,445,501
Ensembl chr 7:46,409,890...46,445,488
JBrowse link
G Hps6 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 IAGP MGI PMID:6696991 NCBI chr19:45,991,917...45,994,612
Ensembl chr19:45,991,947...45,994,612
JBrowse link
G Lyst lysosomal trafficking regulator IAGP MGI PMID:6696991 NCBI chr13:13,764,896...13,953,388
Ensembl chr13:13,764,982...13,953,388
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b IAGP MGI PMID:23112346 NCBI chr17:35,281,669...35,285,761
Ensembl chr17:35,281,669...35,285,160
JBrowse link
G Pdia4 protein disulfide isomerase associated 4 IAGP MGI PMID:28576878 NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:12070017 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rab32 RAB32, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
JBrowse link
G Rab38 RAB38, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr 7:88,079,481...88,140,780
Ensembl chr 7:88,079,481...88,140,780
JBrowse link
decreased platelet calcium level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino IAGP MGI PMID:11110696 NCBI chr 5:36,904,718...36,906,023
Ensembl chr 5:36,904,722...36,905,994
JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IAGP MGI PMID:12586747 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) IAGP MGI PMID:12586747 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 IAGP MGI PMID:18952890 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:15705797 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Plcb2 phospholipase C, beta 2 IAGP MGI PMID:10669417 NCBI chr 2:118,535,484...118,559,140
Ensembl chr 2:118,537,998...118,558,919
JBrowse link
G Plcb3 phospholipase C, beta 3 IAGP MGI PMID:10669417 NCBI chr19:6,931,081...6,951,738
Ensembl chr19:6,929,693...6,953,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP MGI PMID:10727451 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
decreased platelet dense granule number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G a nonagouti IAGP MGI PMID:6696991 NCBI chr 2:154,792,519...154,892,932
Ensembl chr 2:154,633,322...154,892,932
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit IAGP MGI PMID:6696991 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Ap3d1 adaptor-related protein complex 3, delta 1 subunit IAGP MGI PMID:1912584 NCBI chr10:80,542,790...80,578,137
Ensembl chr10:80,542,790...80,578,098
JBrowse link
G Bloc1s4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino IAGP MGI PMID:11110696 NCBI chr 5:36,904,718...36,906,023
Ensembl chr 5:36,904,722...36,905,994
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex-1, subunit 5, muted IAGP MGI PMID:1912584 NCBI chr13:38,786,674...38,821,093
Ensembl chr13:38,776,818...38,819,085
JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin IAGP MGI PMID:6696991 NCBI chr 2:122,580,425...122,591,407
Ensembl chr 2:122,580,423...122,591,395
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 IAGP MGI PMID:1936982 PMID:12923531 NCBI chr13:45,075,552...45,155,614
Ensembl chr13:45,075,551...45,155,623
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 IAGP MGI PMID:9256466 NCBI chr19:42,743,629...42,770,013
Ensembl chr19:42,743,544...42,768,417
JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 IAGP MGI PMID:3408670 NCBI chr 3:20,050,109...20,089,478
Ensembl chr 3:20,050,109...20,089,479
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 IAGP MGI PMID:6696991 NCBI chr 7:46,409,890...46,445,501
Ensembl chr 7:46,409,890...46,445,488
JBrowse link
G Hps6 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 IAGP MGI PMID:6696991 NCBI chr19:45,991,917...45,994,612
Ensembl chr19:45,991,947...45,994,612
JBrowse link
G Kxd1 KxDL motif containing 1 IAGP MGI PMID:22554196 NCBI chr 8:70,966,046...70,975,830
Ensembl chr 8:70,960,922...70,980,606
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:10859366 PMID:12070017 PMID:17384153 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rab27b RAB27B, member RAS oncogene family IAGP MGI PMID:17384153 NCBI chr18:70,112,202...70,274,704
Ensembl chr18:70,112,202...70,274,676
JBrowse link
G Rab32 RAB32, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
JBrowse link
G Rab38 RAB38, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr 7:88,079,481...88,140,780
Ensembl chr 7:88,079,481...88,140,780
JBrowse link
G Rabggta Rab geranylgeranyl transferase, a subunit IAGP MGI PMID:8490171 NCBI chr14:55,953,321...55,959,720
Ensembl chr14:55,952,873...55,959,720
JBrowse link
G Tmem163 transmembrane protein 163 IAGP MGI PMID:33513603 NCBI chr 1:127,418,079...127,605,758
Ensembl chr 1:127,414,283...127,607,285
JBrowse link
decreased platelet serotonin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G a nonagouti IAGP MGI PMID:2369371 PMID:6696991 PMID:12070017 NCBI chr 2:154,792,519...154,892,932
Ensembl chr 2:154,633,322...154,892,932
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit IAGP MGI PMID:6696991 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Ap3d1 adaptor-related protein complex 3, delta 1 subunit IAGP MGI PMID:1912584 NCBI chr10:80,542,790...80,578,137
Ensembl chr10:80,542,790...80,578,098
JBrowse link
G Bloc1s4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino IAGP MGI PMID:11110696 NCBI chr 5:36,904,718...36,906,023
Ensembl chr 5:36,904,722...36,905,994
JBrowse link
G Bloc1s5 biogenesis of lysosomal organelles complex-1, subunit 5, muted IAGP MGI PMID:1912584 NCBI chr13:38,786,674...38,821,093
Ensembl chr13:38,776,818...38,819,085
JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin IAGP MGI PMID:6696991 NCBI chr 2:122,580,425...122,591,407
Ensembl chr 2:122,580,423...122,591,395
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 IAGP MGI PMID:12923531 NCBI chr13:45,075,552...45,155,614
Ensembl chr13:45,075,551...45,155,623
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 IAGP MGI PMID:2369371 PMID:6696991 NCBI chr19:42,743,629...42,770,013
Ensembl chr19:42,743,544...42,768,417
JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 IAGP MGI PMID:3408670 NCBI chr 3:20,050,109...20,089,478
Ensembl chr 3:20,050,109...20,089,479
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 IAGP MGI PMID:2369371 PMID:6696991 NCBI chr 5:112,490,849...112,526,290
Ensembl chr 5:112,490,949...112,526,280
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 IAGP MGI PMID:2369371 PMID:6696991 NCBI chr 7:46,409,890...46,445,501
Ensembl chr 7:46,409,890...46,445,488
JBrowse link
G Hps6 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 IAGP MGI PMID:2369371 PMID:6696991 NCBI chr19:45,991,917...45,994,612
Ensembl chr19:45,991,947...45,994,612
JBrowse link
G Lyst lysosomal trafficking regulator IAGP MGI PMID:6696991 NCBI chr13:13,764,896...13,953,388
Ensembl chr13:13,764,982...13,953,388
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:10859366 PMID:12070017 PMID:17062724 PMID:17384153 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Rab27b RAB27B, member RAS oncogene family IAGP MGI PMID:17384153 NCBI chr18:70,112,202...70,274,704
Ensembl chr18:70,112,202...70,274,676
JBrowse link
G Rab32 RAB32, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr10:10,420,783...10,433,951
Ensembl chr10:10,420,746...10,434,009
JBrowse link
G Rab38 RAB38, member RAS oncogene family IAGP MGI PMID:31399401 NCBI chr 7:88,079,481...88,140,780
Ensembl chr 7:88,079,481...88,140,780
JBrowse link
G Rabggta Rab geranylgeranyl transferase, a subunit IAGP MGI PMID:8490171 NCBI chr14:55,953,321...55,959,720
Ensembl chr14:55,952,873...55,959,720
JBrowse link
G Slc35d3 solute carrier family 35, member D3 IAGP MGI PMID:17062724 NCBI chr10:19,723,662...19,728,195
Ensembl chr10:19,723,662...19,727,205
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 IAGP MGI PMID:8699821 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
increased platelet ATP level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcb2 phospholipase C, beta 2 IAGP MGI PMID:10669417 NCBI chr 2:118,535,484...118,559,140
Ensembl chr 2:118,537,998...118,558,919
JBrowse link
G Plcb3 phospholipase C, beta 3 IAGP MGI PMID:10669417 NCBI chr19:6,931,081...6,951,738
Ensembl chr19:6,929,693...6,953,838
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16931
    hematopoietic system phenotype 5533
      abnormal hematopoietic system morphology/development 5064
        abnormal hematopoietic cell morphology 4231
          abnormal myeloid cell morphology 3072
            abnormal platelet morphology 668
              abnormal platelet dense granule morphology 34
                abnormal platelet ADP level + 11
                abnormal platelet ATP level + 17
                abnormal platelet calcium level + 9
                abnormal platelet dense granule number + 18
                abnormal platelet serotonin level + 20
paths to the root