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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal platelet morphology
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Accession:MP:0004720 term browser browse the term
Definition:any structural anomaly of blood plasma cells derived from megakaryocytes, which function to promote blood clotting
Synonyms:exact_synonym: abnormal platelets morphology;   abnormal thrombocyte morphology;   platelet dysplasia
 related_synonym: abnormal blood platelet morphology


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abnormal platelet dense granule number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab38 RAB38, member RAS oncogene family IAGP RGD PMID:18983523 RGD:2324691 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Rab38ru Rab38, member of RAS oncogene family, ruby allele IAGP RGD PMID:18983523 RGD:2324691
decreased platelet serotonin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab38 RAB38, member RAS oncogene family IAGP RGD PMID:9250486 RGD:1302447 NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924 		JBrowse link
G Rab38ru Rab38, member of RAS oncogene family, ruby allele IAGP RGD PMID:9250486 RGD:1302447
thrombocytopenia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IMP compared to Hsd:SD RGD PMID:23859880 RGD:13204753 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrem2Sage aryl hydrocarbon receptor; ZFN induced mutant2, Sage IMP compared to Hsd:SD RGD PMID:23859880 RGD:13204753
thrombocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F8 coagulation factor VIII IMP as compared to wild type Sprague Dawley RGD PMID:24931420 RGD:11530071 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857 		JBrowse link
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage IMP RGD PMID:24931420 RGD:11530071
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  mammalian phenotype 5373
    hematopoietic system phenotype 243
      abnormal hematopoietic system morphology/development 223
        abnormal hematopoietic cell morphology 179
          abnormal myeloid cell morphology 102
            abnormal platelet morphology 13
              abnormal platelet alpha-granule morphology + 1
              abnormal platelet cell number + 7
              abnormal platelet dense granule morphology + 6
              abnormal platelet shape 0
              abnormal platelet volume + 1
              abnormal thrombopoiesis 0
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