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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal cochlear hair cell inter-stereocilial links morphology
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Accession:MP:0004577 term browser browse the term
Definition:any structural anomaly in the morphologically and biochemically distinct link types that extend between the stereocilia of cochlear hair bundles; link types can be distinguished by their relative sensitivities to treatment with calcium chelators and the protease subtilisin; in the mature mouse cochlea, tip links and horizontal top connectors are the only inter-stereocilial links associated with the hair bundle; ankle links and transient lateral links are both prominent features of developing auditory hair bundles



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Term Annotations click to browse term
  mammalian phenotype 5400
    hearing/vestibular/ear phenotype 23
      abnormal ear morphology 12
        abnormal inner ear morphology 11
          abnormal hair cell morphology 4
            abnormal cochlear hair cell morphology 4
              abnormal cochlear hair cell stereociliary bundle morphology 4
                abnormal cochlear hair cell inter-stereocilial links morphology 0
                  abnormal cochlear hair bundle ankle links morphology + 0
                  abnormal cochlear hair bundle horizontal top connectors morphology 0
                  abnormal cochlear hair bundle tip links morphology 0
                  abnormal cochlear hair bundle transient lateral links morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    hearing/vestibular/ear phenotype 23
      abnormal ear morphology 12
        abnormal inner ear morphology 11
          abnormal membranous labyrinth morphology 11
            abnormal cochlear labyrinth morphology 7
              abnormal scala media morphology 7
                abnormal organ of Corti morphology 4
                  abnormal cochlear hair cell morphology 4
                    abnormal cochlear hair cell stereociliary bundle morphology 4
                      abnormal cochlear hair cell inter-stereocilial links morphology 0
                        abnormal cochlear hair bundle ankle links morphology + 0
                        abnormal cochlear hair bundle horizontal top connectors morphology 0
                        abnormal cochlear hair bundle tip links morphology 0
                        abnormal cochlear hair bundle transient lateral links morphology 0
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