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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal outer hair cell stereociliary bundle morphology
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Accession:MP:0004527 term browser browse the term
Definition:any structural anomaly or disruption of the typical V or W-like pattern of arrangement of mechanosensitive hair bundles located at the apical end of cochlear OHCs; each hair bundle is normally composed of ~100 nonmotile, actin-filled microvilli (stereocilia) arranged in rows of increasing height and coupled to one another by morphologically distinct links: tip links, horizontal top connectors, shaft connectors, and ankle links; most hair bundles also possess a single motile kinocilium immediately adjacent to the tallest (outermost) row of stereocilia; a fifth link type, the kinocilial link, connects the kinocilium to its neighboring stereocilia
Synonyms:exact_synonym: abnormal OHC bundles;   abnormal OHC stereocilia;   abnormal OHC stereociliary bundles


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    hearing/vestibular/ear phenotype 23
      abnormal ear morphology 12
        abnormal inner ear morphology 11
          abnormal hair cell morphology 4
            abnormal cochlear hair cell morphology 4
              abnormal cochlear hair cell stereociliary bundle morphology 4
                abnormal outer hair cell stereociliary bundle morphology 0
                  abnormal orientation of outer hair cell stereociliary bundles 0
                  abnormal outer hair cell kinocilium morphology + 0
                  absent outer hair cell stereocilia 0
                  decreased outer hair cell stereocilia number 0
                  fused outer hair cell stereocilia 0
                  short outer hair cell stereocilia 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    hearing/vestibular/ear phenotype 23
      abnormal ear morphology 12
        abnormal inner ear morphology 11
          abnormal membranous labyrinth morphology 11
            abnormal cochlear labyrinth morphology 7
              abnormal scala media morphology 7
                abnormal organ of Corti morphology 4
                  abnormal cochlear hair cell morphology 4
                    abnormal cochlear hair cell stereociliary bundle morphology 4
                      abnormal outer hair cell stereociliary bundle morphology 0
                        abnormal orientation of outer hair cell stereociliary bundles 0
                        abnormal outer hair cell kinocilium morphology + 0
                        absent outer hair cell stereocilia 0
                        decreased outer hair cell stereocilia number 0
                        fused outer hair cell stereocilia 0
                        short outer hair cell stereocilia 0
paths to the root