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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased incidence of tumors by chemical induction
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Accession:MP:0004499 term browser browse the term
Definition:higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens
Synonyms:exact_synonym: increased incidence of chemically-induced tumors;   increased incidence of chemically-induced tumours;   increased incidence of tumours by chemical induction



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increased incidence of tumors by chemical induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SPRD/Ztm MODEL: induced IAGP compared to 7,12-dimethyltetraphene treated WKY/Ztm RGD PMID:16596452 RGD:1599317
S SS.BN-(D6Rat119-D6Arb3)/Mcwi induced IAGP compared to SS/JrHsdMcwi RGD PMID:20737482 RGD:4143380 NCBI chr 6:106,752,656...132,339,866 JBrowse link
S SS.LEW-(D10Mco84-D10Rat58)/Mco induced IAGP compared to SS/Jr RGD PMID:27073989 RGD:11353863 NCBI chr10:67,502,108...67,785,171 JBrowse link
S STOCK-Tp53tm1(EGFP-Pac)Qly/Rrrc p53 knockout rat IAGP RGD PMID:22791818 RGD:12792958 NCBI chr10:54,300,070...54,311,525 JBrowse link
S WF/NHsd induced IAGP compared to WF.WKY-(D5Wox7-D5Uwm37)/Uwm RGD PMID:12844486 RGD:631852

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    homeostasis/metabolism phenotype 1404
      abnormal physiological response to xenobiotic 28
        increased physiological sensitivity to xenobiotic 5
          increased incidence of tumors by chemical induction 5
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    neoplasm 244
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          increased tumor incidence 166
            increased incidence of induced tumors 19
              increased incidence of tumors by chemical induction 5
paths to the root