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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:cochlear outer hair cell degeneration
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Accession:MP:0004404 term browser browse the term
Definition:degeneration or loss of the columnar outer hair sensory cells of the organ of Corti
Synonyms:exact_synonym: auditory outer hair cell degeneration



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cochlear outer hair cell degeneration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrv1 adhesion G protein-coupled receptor V1 IAGP MGI PMID:16775142 PMID:17295842 NCBI chr13:81,243,187...81,781,504
Ensembl chr13:81,243,187...81,781,273
JBrowse link
G Alg10b ALG10 alpha-1,2-glucosyltransferase IAGP MGI PMID:24303013 NCBI chr15:90,108,506...90,117,674
Ensembl chr15:90,108,514...90,117,674
JBrowse link
G Ap1g1 adaptor protein complex AP-1, gamma 1 subunit IAGP MGI PMID:27090238 NCBI chr 8:110,505,215...110,590,842
Ensembl chr 8:110,505,186...110,590,836
JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:16051453 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Atoh1 atonal bHLH transcription factor 1 IAGP MGI PMID:24265785 NCBI chr 6:64,706,109...64,708,229
Ensembl chr 6:64,706,109...64,708,229
JBrowse link
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 IAGP MGI PMID:10687933 PMID:11875276 PMID:18974863 PMID:21325754 NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
JBrowse link
G Atp8b1 ATPase, class I, type 8B, member 1 IAGP MGI PMID:19478059 NCBI chr18:64,662,050...64,794,342
Ensembl chr18:64,662,038...64,794,338
JBrowse link
G Barhl1 BarH like homeobox 1 IAGP MGI PMID:12091321 NCBI chr 2:28,797,692...28,807,996
Ensembl chr 2:28,797,691...28,806,680
JBrowse link
G Bsnd barttin CLCNK type accessory beta subunit IAGP MGI PMID:18833191 NCBI chr 4:106,340,653...106,349,440
Ensembl chr 4:106,340,653...106,349,480
JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit IAGP MGI PMID:10929716 PMID:12684182 PMID:15357422 PMID:17074442 NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412
JBrowse link
G Casp3 caspase 3 IAGP MGI PMID:11251216 PMID:11374883 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cdc14a CDC14 cell division cycle 14A IAGP MGI PMID:29293958 NCBI chr 3:116,066,202...116,222,390
Ensembl chr 3:116,066,202...116,222,394
JBrowse link
G Cdh23 cadherin related 23 (otocadherin) IAGP MGI PMID:21689626 PMID:22326520 PMID:28287619 NCBI chr10:60,138,527...60,532,291
Ensembl chr10:60,138,527...60,532,269
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D IAGP MGI PMID:12717441 NCBI chr 9:21,199,759...21,202,553
Ensembl chr 9:21,199,706...21,202,703
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 IAGP MGI PMID:12842012 NCBI chr15:85,782,959...85,918,424
Ensembl chr15:85,783,130...85,918,404
JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 IAGP MGI PMID:34732824 NCBI chr 4:8,690,345...8,868,449
Ensembl chr 4:8,690,406...8,867,659
JBrowse link
G Cldn11 claudin 11 IAGP MGI PMID:15306639 NCBI chr 3:31,204,069...31,218,475
Ensembl chr 3:31,204,069...31,218,473
JBrowse link
G Cldn14 claudin 14 IAGP MGI PMID:12913076 NCBI chr16:93,715,919...93,809,733
Ensembl chr16:93,715,919...93,809,696
JBrowse link
G Cldn9 claudin 9 IAGP MGI PMID:19696885 NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000
JBrowse link
G Clic5 chloride intracellular channel 5 IAGP MGI PMID:17021174 NCBI chr17:44,445,671...44,591,059
Ensembl chr17:44,445,659...44,591,059
JBrowse link
G Clrn1 clarin 1 IAGP MGI PMID:29985171 NCBI chr 3:58,751,449...58,792,633
Ensembl chr 3:58,751,449...58,792,761
JBrowse link
G Cmah cytidine monophospho-N-acetylneuraminic acid hydroxylase IAGP MGI PMID:17420276 NCBI chr13:24,511,387...24,661,272
Ensembl chr13:24,511,387...24,661,360
JBrowse link
G Cobl cordon-bleu WH2 repeat IAGP MGI PMID:30157434 NCBI chr11:12,186,676...12,415,022
Ensembl chr11:12,186,608...12,414,960
JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IAGP MGI PMID:17420276 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719
JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 IAGP MGI PMID:25762674 NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947
JBrowse link
G Ercc8 excision repaiross-complementing rodent repair deficiency, complementation group 8 IAGP MGI PMID:25762674 NCBI chr13:108,295,246...108,337,738
Ensembl chr13:108,295,265...108,331,898
JBrowse link
G Espn espin IAGP MGI PMID:1636414 PMID:6871029 NCBI chr 4:152,204,788...152,236,871
Ensembl chr 4:152,204,788...152,236,828
JBrowse link
G Fscn2 fascin actin-bundling protein 2 IAGP MGI PMID:30082328 NCBI chr11:120,250,991...120,258,999
Ensembl chr11:120,252,360...120,258,994
JBrowse link
G Fzd4 frizzled class receptor 4 IAGP MGI PMID:15035989 NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 IAGP MGI PMID:17021187 NCBI chr 7:57,057,417...57,240,808
Ensembl chr 7:57,057,420...57,159,807
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 IAGP MGI PMID:17021187 NCBI chr11:42,310,342...42,523,418
Ensembl chr11:42,310,584...42,519,855
JBrowse link
G Gabrb3 GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3 IAGP MGI PMID:17021187 NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550
JBrowse link
G Gata3 GATA binding protein 3 IAGP MGI PMID:15207274 PMID:15994092 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Gfi1 growth factor independent 1 transcription repressor IAGP MGI PMID:12441305 PMID:15254021 PMID:16397623 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902
JBrowse link
G Gjb2 gap junction protein, beta 2 IAGP MGI PMID:12121617 NCBI chr14:57,336,059...57,342,159
Ensembl chr14:57,336,057...57,342,159
JBrowse link
G Gjb6 gap junction protein, beta 6 IAGP MGI PMID:12490528 PMID:17227867 NCBI chr14:57,360,760...57,370,764
Ensembl chr14:57,360,760...57,371,068
JBrowse link
G Gpx1 glutathione peroxidase 1 IAGP MGI PMID:11545230 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Grid1 glutamate receptor, ionotropic, delta 1 IAGP MGI PMID:17438141 NCBI chr14:34,541,751...35,305,344
Ensembl chr14:34,542,065...35,305,336
JBrowse link
G Hgf hepatocyte growth factor IAGP MGI PMID:32152201 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Ildr1 immunoglobulin-like domain containing receptor 1 IAGP MGI PMID:25217574 PMID:25819842 PMID:25822906 NCBI chr16:36,514,340...36,547,166
Ensembl chr16:36,514,340...36,547,166
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IAGP MGI PMID:12618319 NCBI chr 1:172,168,777...172,201,652
Ensembl chr 1:172,168,777...172,201,652
JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 IAGP MGI PMID:15328414 PMID:17074442 NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559
JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 IAGP MGI PMID:11226272 PMID:15498462 NCBI chr 7:142,660,614...142,980,787
Ensembl chr 7:142,660,099...142,980,779
JBrowse link
G Kcnq4 potassium voltage-gated channel, subfamily Q, member 4 IAGP MGI PMID:16437162 NCBI chr 4:120,553,331...120,605,809
Ensembl chr 4:120,553,335...120,605,809
JBrowse link
G Klc2 kinesin light chain 2 IAGP MGI PMID:34014435 NCBI chr19:5,157,774...5,168,326
Ensembl chr19:5,157,774...5,168,588
JBrowse link
G Lhfpl5 lipoma HMGIC fusion partner-like 5 IAGP MGI PMID:15905332 PMID:17876667 NCBI chr17:28,794,330...28,802,567
Ensembl chr17:28,794,615...28,804,653
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IAGP MGI PMID:26542706 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
JBrowse link
G Marveld2 MARVEL (membrane-associating) domain containing 2 IAGP MGI PMID:23979167 PMID:26677943 NCBI chr13:100,732,465...100,753,479
Ensembl chr13:100,732,465...100,753,479
JBrowse link
G Mir96 microRNA 96 IAGP MGI PMID:19363478 NCBI chr 6:30,169,445...30,169,550
Ensembl chr 6:30,169,445...30,169,550
JBrowse link
G Mpv17 MpV17 mitochondrial inner membrane protein IEA MGI NCBI chr 5:31,298,007...31,311,595
Ensembl chr 5:31,297,998...31,311,595
JBrowse link
G Msrb3 methionine sulfoxide reductase B3 IAGP MGI PMID:24191262 NCBI chr10:120,617,005...120,735,132
Ensembl chr10:120,617,001...120,735,006
JBrowse link
G Myo15a myosin XVA IAGP MGI PMID:29985171 NCBI chr11:60,360,165...60,419,195
Ensembl chr11:60,360,165...60,419,195
JBrowse link
G Myo3a myosin IIIA IAGP MGI PMID:21165622 NCBI chr 2:22,232,360...22,508,693
Ensembl chr 2:22,232,316...22,508,264
JBrowse link
G Myo6 myosin VI IAGP MGI PMID:7493015 PMID:10900098 PMID:20224170 NCBI chr 9:80,072,262...80,219,011
Ensembl chr 9:80,072,313...80,219,011
JBrowse link
G Myo7a myosin VIIA IAGP MGI PMID:18339676 PMID:31824252 NCBI chr 7:97,700,261...97,768,730
Ensembl chr 7:97,700,267...97,768,731
JBrowse link
G Ndp Norrie disease (pseudoglioma) (human) IAGP MGI PMID:12040033 NCBI chr  X:16,751,760...16,778,013
Ensembl chr  X:16,751,760...16,778,013
JBrowse link
G Ocm oncomodulin IAGP MGI PMID:26843644 NCBI chr 5:143,956,615...143,987,691
Ensembl chr 5:143,956,622...143,963,488
JBrowse link
G Pax8 paired box 8 IAGP MGI PMID:14981357 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
JBrowse link
G Pcdh15 protocadherin 15 IAGP MGI PMID:15811708 PMID:16887306 PMID:21427143 NCBI chr10:72,932,003...74,485,663
Ensembl chr10:72,935,174...74,485,569
JBrowse link
G Polg polymerase (DNA directed), gamma IAGP MGI PMID:16870370 NCBI chr 7:79,095,979...79,117,659
Ensembl chr 7:79,095,979...79,116,110
JBrowse link
G Pou1f1 POU domain, class 1, transcription factor 1 IAGP MGI PMID:19176829 NCBI chr16:65,317,398...65,331,904
Ensembl chr16:65,317,397...65,331,183
JBrowse link
G Pou3f4 POU domain, class 3, transcription factor 4 IAGP MGI PMID:23606368 NCBI chr  X:109,857,985...109,862,714
Ensembl chr  X:109,857,886...109,860,813
JBrowse link
G Pou4f3 POU domain, class 4, transcription factor 3 IAGP MGI PMID:9256502 PMID:15254021 PMID:32375046 NCBI chr18:42,527,662...42,529,158
Ensembl chr18:42,527,604...42,530,314
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 IAGP MGI PMID:29590114 NCBI chr 1:97,633,768...97,698,133
Ensembl chr 1:97,633,773...97,698,136
JBrowse link
G Psap prosaposin IAGP MGI PMID:17167097 NCBI chr10:60,113,436...60,138,379
Ensembl chr10:60,113,449...60,138,376
JBrowse link
G Rb1 RB transcriptional corepressor 1 IAGP MGI PMID:16648263 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 IAGP MGI PMID:16945494 PMID:17287522 PMID:26805784 PMID:27383011 NCBI chr 9:20,877,248...20,888,089
Ensembl chr 9:20,873,657...20,888,077
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 IAGP MGI PMID:17287522 NCBI chr13:51,562,654...51,576,833
Ensembl chr13:51,562,675...51,576,833
JBrowse link
G Scarb2 scavenger receptor class B, member 2 IAGP MGI PMID:12620969 NCBI chr 5:92,589,170...92,653,516
Ensembl chr 5:92,589,173...92,654,692
JBrowse link
G Slc12a6 solute carrier family 12, member 6 IAGP MGI PMID:14532115 NCBI chr 2:112,096,659...112,193,508
Ensembl chr 2:112,096,170...112,193,508
JBrowse link
G Slc12a7 solute carrier family 12, member 7 IAGP MGI PMID:11976689 NCBI chr13:73,881,172...73,964,873
Ensembl chr13:73,881,213...73,964,873
JBrowse link
G Slc19a2 solute carrier family 19 (thiamine transporter), member 2 IAGP MGI PMID:16642288 NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954
JBrowse link
G Slc26a4 solute carrier family 26, member 4 IAGP MGI PMID:11152663 PMID:21811566 PMID:24760582 NCBI chr12:31,569,813...31,610,054
Ensembl chr12:31,569,826...31,609,968
JBrowse link
G Slc26a5 solute carrier family 26, member 5 IAGP MGI PMID:12239568 PMID:15207913 NCBI chr 5:22,013,999...22,070,602
Ensembl chr 5:22,015,653...22,070,602
JBrowse link
G Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 IAGP MGI PMID:12808454 PMID:16181686 NCBI chr14:7,669,819...7,766,808
Ensembl chr14:7,669,823...7,767,484
JBrowse link
G Smpx small muscle protein, X-linked IAGP MGI PMID:34722533 NCBI chr  X:156,481,969...156,535,587
Ensembl chr  X:156,481,906...156,535,587
JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:10464373 PMID:10466888 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 IAGP MGI PMID:23348741 NCBI chr 5:139,186,313...139,235,594
Ensembl chr 5:139,186,392...139,235,595
JBrowse link
G Syne4 spectrin repeat containing, nuclear envelope family member 4 IAGP MGI PMID:23348741 NCBI chr 7:30,014,268...30,018,471
Ensembl chr 7:30,014,232...30,018,471
JBrowse link
G Synj2 synaptojanin 2 IAGP MGI PMID:21423608 NCBI chr17:5,991,555...6,106,041
Ensembl chr17:5,991,555...6,094,565
JBrowse link
G Thrb thyroid hormone receptor beta IAGP MGI PMID:12925699 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
JBrowse link
G Tmc1 transmembrane channel-like gene family 1 IAGP MGI PMID:22105175 PMID:22330676 NCBI chr19:20,760,820...20,931,566
Ensembl chr19:20,760,822...20,931,566
JBrowse link
G Tmc2 transmembrane channel-like gene family 2 IAGP MGI PMID:22105175 NCBI chr 2:130,037,114...130,106,365
Ensembl chr 2:130,037,114...130,106,365
JBrowse link
G Tmem63b transmembrane protein 63b IAGP MGI PMID:32375046 NCBI chr17:45,971,102...45,997,212
Ensembl chr17:45,971,097...45,997,831
JBrowse link
G Tmprss3 transmembrane protease, serine 3 IAGP MGI PMID:21454591 NCBI chr17:31,398,237...31,419,478
Ensembl chr17:31,398,239...31,417,951
JBrowse link
G Tmtc4 transmembrane and tetratricopeptide repeat containing 4 IAGP MGI PMID:30188326 NCBI chr14:123,156,383...123,220,697
Ensembl chr14:123,156,383...123,221,447
JBrowse link
G Tomt transmembrane O-methyltransferase IAGP MGI PMID:18794526 NCBI chr 7:101,549,010...101,555,572
Ensembl chr 7:101,547,577...101,555,566
JBrowse link
G Tprn taperin IAGP MGI PMID:27693694 NCBI chr 2:25,152,610...25,159,898
Ensembl chr 2:25,152,630...25,159,897
JBrowse link
G Tub TUB bipartite transcription factor IAGP MGI PMID:7479945 PMID:7612867 NCBI chr 7:108,610,087...108,633,666
Ensembl chr 7:108,549,545...108,633,667
JBrowse link
G Ush1c USH1 protein network component harmonin IAGP MGI PMID:14519688 NCBI chr 7:45,844,774...45,887,984
Ensembl chr 7:45,844,774...45,887,927
JBrowse link
G Ush1g USH1 protein network component sans IAGP MGI PMID:18339676 NCBI chr11:115,206,018...115,214,239
Ensembl chr11:115,206,018...115,212,867
JBrowse link
G Usp53 ubiquitin specific peptidase 53 IAGP MGI PMID:26609154 NCBI chr 3:122,725,142...122,778,184
Ensembl chr 3:122,725,142...122,778,159
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein IAGP MGI PMID:37386014 NCBI chr 5:37,123,448...37,146,326
Ensembl chr 5:37,123,448...37,146,549
JBrowse link
G Whrn whirlin IAGP MGI PMID:12124769 NCBI chr 4:63,333,145...63,414,320
Ensembl chr 4:63,333,147...63,414,228
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16931
    nervous system phenotype 4624
      abnormal nervous system morphology 3658
        neurodegeneration 649
          neuron degeneration 519
            cochlear hair cell degeneration 118
              cochlear outer hair cell degeneration 94
Path 2
Term Annotations click to browse term
  mammalian phenotype 16931
    hearing/vestibular/ear phenotype 1023
      abnormal ear morphology 568
        abnormal inner ear morphology 353
          abnormal membranous labyrinth morphology 305
            abnormal cochlear labyrinth morphology 271
              abnormal scala media morphology 271
                abnormal organ of Corti morphology 242
                  abnormal cochlear hair cell morphology 232
                    cochlear hair cell degeneration 118
                      cochlear outer hair cell degeneration 94
paths to the root