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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal plasmacytoid dendritic cell morphology
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Accession:MP:0004242 term browser browse the term
Definition:any structural anomaly of phagocytic dendritic cells that are morphologically similar to plasma cells, but do not express B lineage markers, and produce large amounts of alpha/beta interferons (IFN-/) in response to viral and bacterial stimuli; plasmacytoid dendritic cells are found in the thymic medulla and lymph node T cell areas and are responsible for immune tolerance
Synonyms:exact_synonym: abnormal DC2;   abnormal T-associated plasma cells;   abnormal lymphoid dendritic cell;   abnormal pDC;   abnormal plasmacytoid T cell;   abnormal plasmacytoid monocytes



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  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal professional antigen presenting cell morphology 39
            abnormal dendritic cell morphology 3
              abnormal plasmacytoid dendritic cell morphology 0
                abnormal plasmacytoid dendritic cell number + 0
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