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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:insulitis
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Accession:MP:0004031 term browser browse the term
Definition:a histological change in the islets of Langerhans characterized by edema and the infiltration of small numbers of white blood cells
Synonyms:exact_synonym: intra-insulitis
 narrow_synonym: benign insulitis
 xref: EFO:0002502



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insulitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700016L21Rik RIKEN cDNA 1700016L21 gene IAGP MGI PMID:17911589 NCBI chr 1:80,423,649...80,453,377
Ensembl chr 1:80,405,912...80,457,752
JBrowse link
G Aire autoimmune regulator IAGP MGI PMID:18414681 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444
JBrowse link
G B2m beta-2 microglobulin IAGP MGI PMID:8258349 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G C3 complement component 3 IAGP MGI PMID:17446931 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:15467837 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cd38 CD38 antigen IAGP MGI PMID:16585549 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717
JBrowse link
G Cd40lg CD40 ligand IAGP MGI PMID:15467837 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402
JBrowse link
G Cd80 CD80 antigen IAGP MGI PMID:10795741 PMID:16886063 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697
JBrowse link
G Cd86 CD86 antigen IAGP MGI PMID:10795741 PMID:16886063 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Ciita class II transactivator IAGP MGI PMID:15446308 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IAGP MGI PMID:11035773 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Ctsb cathepsin B IAGP MGI PMID:19664906 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
JBrowse link
G Ctsl cathepsin L IAGP MGI PMID:19664906 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
JBrowse link
G Ctss cathepsin S IAGP MGI PMID:19664906 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
JBrowse link
G E2f1 E2F transcription factor 1 IAGP MGI PMID:15470032 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:10946317 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Flicr Foxp3 regulating long intergenic noncoding RNA IAGP MGI PMID:28396406 NCBI chr  X:7,439,839...7,447,255
Ensembl chr  X:7,439,839...7,447,266
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 IAGP MGI PMID:8258349 PMID:14764740 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-D1 histocompatibility 2, D region locus 1 IAGP MGI PMID:29472249 NCBI chr17:35,482,070...35,486,473
Ensembl chr17:35,481,706...35,486,475
JBrowse link
G Icos inducible T cell co-stimulator IAGP MGI PMID:18292537 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479
JBrowse link
G Ighm immunoglobulin heavy constant mu IAGP MGI PMID:11698422 PMID:12516557 PMID:15448087 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350
JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:9703318 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Ins2 insulin II IAGP MGI PMID:12925730 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 IAGP MGI PMID:24696448 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IAGP MGI PMID:34420035 NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202
JBrowse link
G Mertk MER proto-oncogene tyrosine kinase IAGP MGI PMID:19251650 NCBI chr 2:128,540,836...128,645,082
Ensembl chr 2:128,540,876...128,644,814
JBrowse link
G Mtus1 mitochondrial tumor suppressor 1 IAGP MGI PMID:22200760 NCBI chr 8:41,443,949...41,587,318
Ensembl chr 8:41,443,951...41,586,763
JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:17911591 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 IAGP MGI PMID:16606670 NCBI chr19:29,388,319...29,450,327
Ensembl chr19:29,388,319...29,448,561
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) IAGP MGI PMID:15996660 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:9314549 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Ptprn protein tyrosine phosphatase receptor type N IAGP MGI PMID:14614561 NCBI chr 1:75,223,679...75,241,437
Ensembl chr 1:75,223,671...75,241,146
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:16804066 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 IAGP MGI PMID:23825225 NCBI chr15:97,637,886...97,666,300
Ensembl chr15:97,642,651...97,665,853
JBrowse link
G Stat4 signal transducer and activator of transcription 4 IAGP MGI PMID:10553062 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348
JBrowse link
G Tlr2 toll-like receptor 2 IAGP MGI PMID:17707128 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IAGP MGI PMID:23974926 NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    endocrine/exocrine gland phenotype 3451
      abnormal gland physiology 924
        abnormal pancreas physiology 387
          pancreas inflammation 108
            insulitis 40
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    immune system phenotype 5709
      abnormal immune system physiology 3489
        abnormal inflammatory response 1808
          increased inflammatory response 1539
            pancreas inflammation 108
              insulitis 40
paths to the root