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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal vascular endothelial cell physiology
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Accession:MP:0004003 term browser browse the term
Definition:anomaly in the function of the cells that line the vasculature


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abnormal vascular endothelial cell physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aggf1 angiogenic factor with G patch and FHA domains 1 IAGP MGI PMID:27522498 NCBI chr13:95,487,191...95,511,865
Ensembl chr13:95,487,191...95,511,860 		JBrowse link
G Anxa1 annexin A1 IAGP MGI PMID:19805119 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 IAGP MGI PMID:23372835 NCBI chr 3:62,244,946...62,369,642
Ensembl chr 3:62,245,765...62,369,642 		JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 IAGP MGI PMID:19897489 NCBI chr 1:34,717,263...34,851,819
Ensembl chr 1:34,717,269...34,852,390 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 IAGP MGI PMID:24920669 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous IAGP MGI PMID:9374548 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin IAGP MGI PMID:12485443 NCBI chr 2:122,580,425...122,591,407
Ensembl chr 2:122,580,423...122,591,395 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IAGP MGI PMID:16100039 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Cbs cystathionine beta-synthase IAGP MGI PMID:10993757 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Cd151 CD151 antigen IAGP MGI PMID:17023588 NCBI chr 7:141,047,275...141,051,394
Ensembl chr 7:141,047,305...141,051,386 		JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:16816384 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Clic4 chloride intracellular channel 4 IAGP MGI PMID:19197003 NCBI chr 4:134,941,280...135,000,071
Ensembl chr 4:134,941,280...135,000,125 		JBrowse link
G Ctss cathepsin S IAGP MGI PMID:12600886 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714 		JBrowse link
G Cttn cortactin IAGP MGI PMID:21788407 NCBI chr 7:143,989,468...144,024,743
Ensembl chr 7:143,989,470...144,024,746 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IAGP MGI PMID:10470077 NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046 		JBrowse link
G Epn1 epsin 1 IAGP MGI PMID:23187125 NCBI chr 7:5,083,207...5,101,178
Ensembl chr 7:5,083,234...5,101,177 		JBrowse link
G Epn2 epsin 2 IAGP MGI PMID:23187125 NCBI chr11:61,406,709...61,470,560
Ensembl chr11:61,408,075...61,470,513 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) IAGP MGI PMID:24371309 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fbn1 fibrillin 1 IAGP MGI PMID:12485443 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Flna filamin, alpha IAGP MGI PMID:17172441 NCBI chr  X:73,267,067...73,293,787
Ensembl chr  X:73,267,067...73,293,426 		JBrowse link
G H2az2 H2A.Z histone variant 2 IAGP MGI PMID:17172441 NCBI chr11:6,377,226...6,394,511
Ensembl chr11:6,377,229...6,394,443 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:22733797 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:10329607 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Igf1r insulin-like growth factor I receptor IAGP MGI PMID:22733797 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Krit1 KRIT1, ankyrin repeat containing IAGP MGI PMID:24990152 NCBI chr 5:3,853,156...3,894,515
Ensembl chr 5:3,853,184...3,895,564 		JBrowse link
G Lipg lipase, endothelial IAGP MGI PMID:15485805 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334 		JBrowse link
G Lypla1 lysophospholipase 1 IAGP MGI PMID:32233916 NCBI chr 1:4,878,046...4,916,958
Ensembl chr 1:4,878,011...4,918,633 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid IAGP MGI PMID:24828040 NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 IAGP MGI PMID:15743827 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479 		JBrowse link
G Ngf nerve growth factor IAGP MGI PMID:23091165 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal IAGP MGI PMID:18413498 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IAGP MGI PMID:18413498 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell IAGP MGI PMID:18413498 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit IAGP MGI PMID:26755743 NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279 		JBrowse link
G P2rx4 purinergic receptor P2X, ligand-gated ion channel 4 IAGP MGI PMID:16327800 NCBI chr 5:122,845,581...122,867,802
Ensembl chr 5:122,845,607...122,867,801 		JBrowse link
G Palmd palmdelphin IAGP MGI PMID:34636652 NCBI chr 3:116,711,911...116,762,896
Ensembl chr 3:116,711,907...116,762,636 		JBrowse link
G Piezo1 piezo-type mechanosensitive ion channel component 1 IAGP MGI PMID:25119035 NCBI chr 8:123,208,437...123,278,068
Ensembl chr 8:123,208,437...123,278,068 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma IAGP MGI PMID:19666848 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptafr platelet-activating factor receptor IAGP MGI PMID:16299272 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 IAGP MGI PMID:18414683 NCBI chr18:10,064,401...10,182,225
Ensembl chr18:10,064,401...10,182,045 		JBrowse link
G Sdc2 syndecan 2 IAGP MGI PMID:30952866 NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081 		JBrowse link
G Slc4a7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 IAGP MGI PMID:21947296 NCBI chr14:7,669,819...7,766,808
Ensembl chr14:7,669,823...7,767,484 		JBrowse link
G Sox18 SRY (sex determining region Y)-box 18 IAGP MGI PMID:19429912 NCBI chr 2:181,311,630...181,313,433
Ensembl chr 2:181,311,629...181,313,433 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 IAGP MGI PMID:17786199 NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482 		JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:16782872 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045 		JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:16782872 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014 		JBrowse link
abnormal vascular endothelial cell adhesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lypla1 lysophospholipase 1 IAGP MGI PMID:32233916 NCBI chr 1:4,878,046...4,916,958
Ensembl chr 1:4,878,011...4,918,633 		JBrowse link
decreased lung endothelial cell adhesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Podxl podocalyxin-like IAGP MGI PMID:25303643 NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916 		JBrowse link
decreased vascular endothelial cell apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator IAGP MGI PMID:21593423 NCBI chr18:35,846,139...35,855,460
Ensembl chr18:35,846,139...35,855,409 		JBrowse link
decreased vascular endothelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif 7 IAGP MGI PMID:25712208 NCBI chr 9:90,041,420...90,082,155
Ensembl chr 9:90,045,122...90,090,124 		JBrowse link
G Anxa1 annexin A1 IAGP MGI PMID:19805119 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver IAGP MGI PMID:25830893 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Git1 GIT ArfGAP 1 IAGP MGI PMID:19273721 NCBI chr11:77,384,114...77,398,600
Ensembl chr11:77,384,388...77,398,612 		JBrowse link
G H2ax H2A.X variant histone IAGP MGI PMID:23254285 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit IAGP MGI PMID:15542432 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:19458618 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Nostrin nitric oxide synthase trafficker IAGP MGI PMID:22751148 NCBI chr 2:68,966,144...69,019,674
Ensembl chr 2:68,966,144...69,019,674 		JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein IAGP MGI PMID:19154719 NCBI chr 2:25,070,770...25,073,351
Ensembl chr 2:25,070,770...25,073,351 		JBrowse link
G Rac2 Rac family small GTPase 2 IAGP MGI PMID:18068132 NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Sdc2 syndecan 2 IAGP MGI PMID:30952866 NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081 		JBrowse link
increased lung endothelial cell adhesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Podxl podocalyxin-like IAGP MGI PMID:25303643 NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916 		JBrowse link
increased vascular endothelial cell adhesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing IAGP MGI PMID:17549259 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
increased vascular endothelial cell apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 IAGP MGI PMID:20019329 NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545 		JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain IAGP MGI PMID:19411629 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116 		JBrowse link
G Ets2 E26 avian leukemia oncogene 2, 3' domain IAGP MGI PMID:19411629 NCBI chr16:95,503,274...95,522,093
Ensembl chr16:95,502,942...95,522,095 		JBrowse link
G H2ax H2A.X variant histone IAGP MGI PMID:19377486 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein IAGP MGI PMID:17717145 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit IAGP MGI PMID:26755743 NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IAGP MGI PMID:22975327 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721 		JBrowse link
increased vascular endothelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 IAGP MGI PMID:20019329 NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545 		JBrowse link
G Epn1 epsin 1 IAGP MGI PMID:23187125 NCBI chr 7:5,083,207...5,101,178
Ensembl chr 7:5,083,234...5,101,177 		JBrowse link
G Epn2 epsin 2 IAGP MGI PMID:23187125 NCBI chr11:61,406,709...61,470,560
Ensembl chr11:61,408,075...61,470,513 		JBrowse link
G Erg ETS transcription factor IAGP MGI PMID:25062690 NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452 		JBrowse link
G Lif leukemia inhibitory factor IAGP MGI PMID:18521186 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16532
    cardiovascular system phenotype 4054
      abnormal cardiovascular system physiology 2291
        abnormal vasculature physiology 480
          abnormal blood vessel physiology 461
            abnormal vascular endothelial cell physiology 64
              abnormal vascular endothelial cell adhesion + 3
              abnormal vascular endothelial cell apoptosis + 8
              abnormal vascular endothelial cell proliferation + 16
paths to the root