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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal adrenocorticotropin level
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Accession:MP:0003966 term browser browse the term
Definition:anomaly in the level of the pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex
Synonyms:exact_synonym: abnormal levels of ACTH;   abnormal levels of adrenocorticotropic hormone;   abnormal levels of adrenocorticotropin;   abnormal levels of adrenotropic hormone;   abnormal levels of adrenotropin


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abnormal adrenocorticotropin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd adrenocortical dysplasia IAGP MGI PMID:8014601 NCBI chr 8:106,424,789...106,427,748
Ensembl chr 8:106,422,492...106,427,734 		JBrowse link
G Crh corticotropin releasing hormone IAGP MGI PMID:10686522 PMID:11602623 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IAGP MGI PMID:16631135 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Ogn osteoglycin IAGP MGI PMID:21664248 NCBI chr13:49,761,491...49,777,977
Ensembl chr13:49,761,522...49,777,977 		JBrowse link
decreased adrenocorticotropin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnrh1 gonadotropin releasing hormone 1 IAGP MGI PMID:198666 NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888 		JBrowse link
G Insm1 insulinoma-associated 1 IAGP MGI PMID:24227653 NCBI chr 2:146,064,021...146,066,940
Ensembl chr 2:146,063,841...146,066,940 		JBrowse link
G Lhx3 LIM homeobox protein 3 IAGP MGI PMID:8638120 PMID:21149718 NCBI chr 2:26,090,224...26,098,261
Ensembl chr 2:26,090,224...26,098,301 		JBrowse link
G Pax6 paired box 6 IAGP MGI PMID:19034419 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IAGP MGI PMID:12145326 PMID:35245347 NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980 		JBrowse link
G Phf6 PHD finger protein 6 IAGP MGI PMID:32994169 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820 		JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:17095588 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 IAGP MGI PMID:16932809 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610 		JBrowse link
decreased circulating adrenocorticotropin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1b arginine vasopressin receptor 1B IAGP MGI PMID:14722621 NCBI chr 1:131,526,908...131,539,740
Ensembl chr 1:131,526,977...131,539,738 		JBrowse link
G Cpe carboxypeptidase E IAGP MGI PMID:9144234 NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088 		JBrowse link
G Crh corticotropin releasing hormone IAGP MGI PMID:27595593 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Ddx20 DEAD box helicase 20 IAGP MGI PMID:18258677 NCBI chr 3:105,585,586...105,595,104
Ensembl chr 3:105,585,586...105,594,890 		JBrowse link
G Lif leukemia inhibitory factor IAGP MGI PMID:8770940 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IAGP MGI PMID:10471508 PMID:19017639 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 IAGP MGI PMID:22232675 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Pde8b phosphodiesterase 8B IAGP MGI PMID:21187369 NCBI chr13:95,160,962...95,386,904
Ensembl chr13:95,160,962...95,386,844 		JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:10470087 PMID:12458044 PMID:17095588 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) IAGP MGI PMID:12642666 NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382 		JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) IAGP MGI PMID:12642666 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525 		JBrowse link
G Tbx19 T-box 19 IAGP MGI PMID:12651892 NCBI chr 1:164,965,403...164,988,342
Ensembl chr 1:164,965,424...164,988,342 		JBrowse link
increased adrenocorticotropin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd adrenocortical dysplasia IAGP MGI PMID:8014601 NCBI chr 8:106,424,789...106,427,748
Ensembl chr 8:106,422,492...106,427,734 		JBrowse link
G Anxa1 annexin A1 IAGP MGI PMID:17026533 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Armc5 armadillo repeat containing 5 IAGP MGI PMID:28911199 NCBI chr 7:127,836,460...127,844,272
Ensembl chr 7:127,836,514...127,844,272 		JBrowse link
G Cort cortistatin IAGP MGI PMID:21971153 NCBI chr 4:149,209,491...149,211,132
Ensembl chr 4:149,209,491...149,211,220 		JBrowse link
G Lep leptin IAGP MGI PMID:6393185 PMID:21554665 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein IAGP MGI PMID:29879378 NCBI chr16:90,535,095...90,546,673
Ensembl chr16:90,535,095...90,546,673 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IAGP MGI PMID:10471508 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Scg5 secretogranin V IAGP MGI PMID:10089884 NCBI chr 2:113,606,708...113,659,423
Ensembl chr 2:113,606,707...113,659,466 		JBrowse link
G Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 IAGP MGI PMID:16980625 NCBI chr12:103,612,889...103,623,477
Ensembl chr12:103,612,889...103,623,471 		JBrowse link
G Star steroidogenic acute regulatory protein IAGP MGI PMID:9326645 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010 		JBrowse link
increased circulating adrenocorticotropin level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 IAGP MGI PMID:12218346 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Cnr1 cannabinoid receptor 1 IAGP MGI PMID:15078564 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cort cortistatin IAGP MGI PMID:21971153 NCBI chr 4:149,209,491...149,211,132
Ensembl chr 4:149,209,491...149,211,220 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IAGP MGI PMID:12973355 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IAGP MGI PMID:12145347 PMID:22962254 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Cyp11b1 steroid-11-beta-hydroxylase IAGP MGI PMID:19029289 NCBI chr15:74,706,741...74,713,492
Ensembl chr15:74,705,974...74,713,492 		JBrowse link
G Drd2 dopamine receptor D2 IAGP MGI PMID:9717839 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477 		JBrowse link
G Grid2 glutamate receptor, ionotropic, delta 2 IAGP MGI PMID:9387853 NCBI chr 6:63,230,118...64,681,305
Ensembl chr 6:63,232,860...64,681,307 		JBrowse link
G Mc2r melanocortin 2 receptor IAGP MGI PMID:17989225 NCBI chr18:68,539,970...68,562,391
Ensembl chr18:68,539,978...68,562,391 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IAGP MGI PMID:7628695 PMID:22232675 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 IAGP MGI PMID:24619096 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:17095588 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Shh sonic hedgehog IAGP MGI PMID:20118198 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) IAGP MGI PMID:22681886 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296 		JBrowse link
G Sstr2 somatostatin receptor 2 IAGP MGI PMID:11029646 NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854 		JBrowse link
G Tlr2 toll-like receptor 2 IAGP MGI PMID:15546996 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Ucn2 urocortin 2 IAGP MGI PMID:16707802 NCBI chr 9:108,815,231...108,816,232
Ensembl chr 9:108,815,078...108,816,232 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    homeostasis/metabolism phenotype 7865
      abnormal homeostasis 7015
        abnormal hormone level 1305
          abnormal pituitary hormone level 274
            abnormal adrenocorticotropin level 43
              decreased adrenocorticotropin level + 19
              increased adrenocorticotropin level + 25
paths to the root