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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to induced arthritis
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Accession:MP:0003724 term browser browse the term
Definition:more likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents
Synonyms:exact_synonym: decreased resistance to induced arthritis



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increased susceptibility to induced arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash1l ASH1 like histone lysine methyltransferase IAGP MGI PMID:24012418 NCBI chr 3:88,857,721...88,986,682
Ensembl chr 3:88,857,929...88,986,682
JBrowse link
G C1qtnf3 C1q and tumor necrosis factor related protein 3 IAGP MGI PMID:24269820 NCBI chr15:10,952,418...10,980,248
Ensembl chr15:10,952,418...10,980,236
JBrowse link
G C1qtnf6 C1q and tumor necrosis factor related protein 6 IAGP MGI PMID:26404464 NCBI chr15:78,407,546...78,416,370
Ensembl chr15:78,407,546...78,415,616
JBrowse link
G Cd200 CD200 molecule IAGP MGI PMID:11099416 NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416
JBrowse link
G Cd274 CD274 antigen IAGP MGI PMID:21061440 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:15596723 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd59a CD59a antigen IAGP MGI PMID:15457473 NCBI chr 2:103,926,177...103,945,755
Ensembl chr 2:103,926,146...103,945,699
JBrowse link
G Clec4a2 C-type lectin domain family 4, member a2 IAGP MGI PMID:18204462 NCBI chr 6:123,099,627...123,119,891
Ensembl chr 6:123,083,387...123,120,958
JBrowse link
G Cry1 cryptochrome circadian regulator 1 IAGP MGI PMID:20042581 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Cry2 cryptochrome circadian regulator 2 IAGP MGI PMID:20042581 NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388
JBrowse link
G Cytl1 cytokine-like 1 IAGP MGI PMID:21652695 NCBI chr 5:37,892,863...37,897,164
Ensembl chr 5:37,892,863...37,897,164
JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:22179202 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
JBrowse link
G Dusp1 dual specificity phosphatase 1 IAGP MGI PMID:16424221 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Edil3 EGF-like repeats and discoidin I-like domains 3 IAGP MGI PMID:27505251 NCBI chr13:88,969,591...89,471,344
Ensembl chr13:88,969,591...89,471,342
JBrowse link
G Erg ETS transcription factor IAGP MGI PMID:26097038 NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IAGP MGI PMID:12528127 PMID:21724994 PMID:23109709 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G Ffar2 free fatty acid receptor 2 IAGP MGI PMID:19865172 NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200
JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:22179202 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384
JBrowse link
G Fpr2 formyl peptide receptor 2 IAGP MGI PMID:20107188 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214
JBrowse link
G Hc hemolytic complement IAGP MGI PMID:9485083 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:9164973 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Ighm immunoglobulin heavy constant mu IAGP MGI PMID:20111715 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350
JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:11994477 PMID:37315560 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1r2 interleukin 1 receptor, type II IAGP MGI PMID:25725107 NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391
JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:20112392 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:19620301 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:24012418 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:19109195 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 IAGP MGI PMID:18282810 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:20112392 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mir140 microRNA 140 IAGP MGI PMID:20466812 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945
JBrowse link
G Myl3 myosin, light polypeptide 3 IAGP MGI PMID:37794006 NCBI chr 9:110,592,746...110,598,870
Ensembl chr 9:110,570,929...110,598,866
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 IAGP MGI PMID:15310853 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Nudt7 nudix hydrolase 7 IAGP MGI PMID:30143643 NCBI chr 8:114,860,314...114,881,471
Ensembl chr 8:114,860,297...114,881,479
JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 IAGP MGI PMID:14613294 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IAGP MGI PMID:19218085 NCBI chr 7:18,618,615...18,624,363
Ensembl chr 7:18,605,256...18,624,384
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma IAGP MGI PMID:10549291 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Selp selectin, platelet IAGP MGI PMID:10453030 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IAGP MGI PMID:17510322 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod3 superoxide dismutase 3, extracellular IAGP MGI PMID:15529385 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:15684036 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tmem178 transmembrane protein 178 IAGP MGI PMID:26644563 NCBI chr17:81,252,061...81,309,245
Ensembl chr17:81,252,061...81,309,245
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 IAGP MGI PMID:12577054 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:19841086 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    skeleton phenotype 3370
      abnormal skeleton physiology 859
        abnormal joint physiology 227
          joint inflammation 210
            autoimmune arthritis 175
              increased susceptibility to induced arthritis 71
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    immune system phenotype 5709
      abnormal immune system physiology 3489
        abnormal immune tolerance 666
          abnormal self tolerance 653
            autoimmune response 651
              abnormal susceptibility to autoimmune disorder 500
                increased susceptibility to autoimmune disorder 311
                  increased susceptibility to induced arthritis 71
paths to the root