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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:abnormal hypodermis morphology
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Accession:MP:0003705 term browser browse the term
Definition:any structural anomaly of the irregular layer of loose connective tissue containing fibroblasts, adipose cells, and macrophages, that is immediately deep to the skin and superficial to the deep fascia; usually consisting primarily of a fatty layer and may also include a muscle layer and/or a fibrous layer, or it may occur as a membranous layer only, being nearly devoid of fat; it contains skin ligaments extending between the dermis and deep fascia, cutaneous nerves, and superficial vessels, with terminal branches passing into the skin layers
Synonyms:exact_synonym: abnormal stratum subcutaneum morphology;   abnormal subcutaneous tissue morphology;   abnormal subcutis morphology;   abnormal superficial fascia morphology;   abnormal tela subcutanea morphology;   hypodermal dysplasia
 related_synonym: abnormal hypoderm morphology

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increased subcutaneous adipose tissue amount term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfb complement factor B IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfbem1Tja complement factor B, ZFN induced mutant 1, Tja IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403
G Mc4r melanocortin 4 receptor IMP RGD PMID:21527895 RGD:6478803 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:21527895 RGD:6478803

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  mammalian phenotype 5417
    integument phenotype 171
      abnormal skin adnexa morphology 169
        abnormal hypodermis morphology 9
          abnormal hypodermis fat layer morphology + 9
          abnormal hypodermis muscle layer morphology + 0
          increased hypodermis neovascularization 0
          subcutaneous edema 0
          thick hypodermis 0
          thin hypodermis 0
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