rheumatoid arthritis - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	rheumatoid arthritis	go back to main search page
Accession:	MP:0003561	browse the term
Definition:	an autoimmune response that primarily affects connective tissue; it also results in chronic inflammation of the joints, especially of the hands and feet and may also cause inflammation of the tissue around the joints, as well as other organs in the body
Synonyms:	exact_synonym:	osteoarthrosis deformans
	narrow_synonym:	ACPA-negative rheumatoid arthritis; ACPA-positive rheumatoid arthritis
	xref:	EFO:0000685; EFO:0009459; EFO:0009460

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Rat (9) Mouse (16) Human (0) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Strains (9)

rheumatoid arthritis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

S

DA.F344-(D10Arb20-D10Arb22)/Arb

induced
penetrance

RGD

PMID:12209529 PMID:12209529

RGD:629569, RGD:629569

NCBI chr10:23,444,813...104,060,283

S

DA.F344-(D10Rat204-D10Arb22)/Arb

induced
penetrance

RGD

PMID:12209529 PMID:12209529

RGD:629569, RGD:629569

NCBI chr10:104,060,133...104,060,283

S

DA.F344-(D4Arb30-D4Arb4)/Arb

induced
penetrance

RGD

PMID:12209529 PMID:12209529

RGD:629569, RGD:629569

NCBI chr 4:151,805,502...151,805,662

S

DA.F344-(D7Rat22-D7Mit2)/Nsi

induced

RGD

NCBI chr 7:116,294,265...116,294,546

S

DA.F344-(D8Arb15-D8Arb22)/Arb

induced
penetrance

RGD

PMID:12209529 PMID:12209529

RGD:629569, RGD:629569

NCBI chr 8:68,133,439...119,085,047

S

induced

RGD

S

severity

compared to control strains PVG.1AV1/Kini, LEW.1AV1/Kini

RGD

S

severity

compared to control strain E3/ZtmRhd

RGD

S

LEW/Ztm

penetrance

RGD

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5380
immune system phenotype	495
abnormal immune system physiology	380
abnormal immune tolerance	116
abnormal self tolerance	116
autoimmune response	116
rheumatoid arthritis	9
Path 2
Term	Annotations
mammalian phenotype	5380
immune system phenotype	495
abnormal immune system physiology	380
abnormal inflammatory response	228
increased inflammatory response	220
joint inflammation	101
arthritis	47
rheumatoid arthritis	9

paths to the root