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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:rheumatoid arthritis
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Accession:MP:0003561 term browser browse the term
Definition:an autoimmune response that primarily affects connective tissue; it also results in chronic inflammation of the joints, especially of the hands and feet and may also cause inflammation of the tissue around the joints, as well as other organs in the body
Synonyms:exact_synonym: osteoarthrosis deformans
 narrow_synonym: ACPA-negative rheumatoid arthritis;   ACPA-positive rheumatoid arthritis
 xref: EFO:0000685;   EFO:0009459;   EFO:0009460



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rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S DA.F344-(D10Arb20-D10Arb22)/Arb induced
penetrance
IAGP RGD PMID:12209529 PMID:12209529 RGD:629569, RGD:629569 NCBI chr10:23,444,813...104,060,283 JBrowse link
S DA.F344-(D10Rat204-D10Arb22)/Arb induced
penetrance
IAGP RGD PMID:12209529 PMID:12209529 RGD:629569, RGD:629569 NCBI chr10:104,060,133...104,060,283 JBrowse link
S DA.F344-(D4Arb30-D4Arb4)/Arb induced
penetrance
IAGP RGD PMID:12209529 PMID:12209529 RGD:629569, RGD:629569 NCBI chr 4:151,805,502...151,805,662 JBrowse link
S DA.F344-(D7Rat22-D7Mit2)/Nsi induced IAGP RGD PMID:12209529 RGD:629569 NCBI chr 7:116,294,265...116,294,546 JBrowse link
S DA.F344-(D8Arb15-D8Arb22)/Arb induced
penetrance
IAGP RGD PMID:12209529 PMID:12209529 RGD:629569, RGD:629569 NCBI chr 8:68,133,439...119,085,047 JBrowse link
S DA/BklArbN induced IAGP RGD PMID:12209529 RGD:629569
S DA/ZtmKini severity IAGP compared to control strains PVG.1AV1/Kini, LEW.1AV1/Kini RGD PMID:12915467 RGD:730281
S DXE2/Ztm severity IAGP compared to control strain E3/ZtmRhd RGD PMID:11090241 RGD:629570
S LEW/Ztm LEW/Ztm penetrance IAGP RGD PMID:15081107 RGD:1299867

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5415
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal immune tolerance 116
          abnormal self tolerance 116
            autoimmune response 116
              rheumatoid arthritis 9
Path 2
Term Annotations click to browse term
  mammalian phenotype 5415
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal inflammatory response 229
          increased inflammatory response 221
            joint inflammation 101
              arthritis 47
                rheumatoid arthritis 9
paths to the root