Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Community Projects Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:aneurysm
go back to main search page
Accession:MP:0003279 term browser browse the term
Definition:a protruding sac formed by the dilation of the wall of an artery, a vein, or the heart resulting from a weakening of the vessel wall or heart muscle
Synonyms:xref: Fyler:2399


show annotations for term's descendants           Sort by:
aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IAGP MGI PMID:1115218 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 IAGP MGI PMID:19855011 NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545 		JBrowse link
G Fli1 Friend leukemia integration 1 IAGP MGI PMID:20228226 NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157 		JBrowse link
G Hspg2 perlecan (heparan sulfate proteoglycan 2) IAGP MGI PMID:10579729 NCBI chr 4:137,196,062...137,297,941
Ensembl chr 4:137,196,080...137,297,941 		JBrowse link
G Htra1 HtrA serine peptidase 1 IAGP MGI PMID:21844367 NCBI chr 7:130,537,933...130,587,388
Ensembl chr 7:130,537,841...130,587,390 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:10637274 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) IAGP MGI PMID:9367982 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500 		JBrowse link
G Mgp matrix Gla protein IAGP MGI PMID:12391016 NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821 		JBrowse link
G Mrtfb myocardin related transcription factor B IAGP MGI PMID:22899851 NCBI chr16:13,073,913...13,235,393
Ensembl chr16:13,074,345...13,235,393 		JBrowse link
G Ntf3 neurotrophin 3 IAGP MGI PMID:8841198 NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873 		JBrowse link
G Parva parvin, alpha IAGP MGI PMID:19798050 NCBI chr 7:112,027,102...112,190,899
Ensembl chr 7:112,026,712...112,190,899 		JBrowse link
G Runx1 runt related transcription factor 1 IAGP MGI PMID:10943840 PMID:20647008 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037 		JBrowse link
G Sgcb sarcoglycan, beta (dystrophin-associated glycoprotein) IAGP MGI PMID:10678176 NCBI chr 5:73,790,092...73,805,080
Ensembl chr 5:73,790,092...73,805,133 		JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 IAGP MGI PMID:25596186 NCBI chr 1:4,561,151...4,567,624
Ensembl chr 1:4,561,154...4,567,577 		JBrowse link
G Spp1 secreted phosphoprotein 1 IAGP MGI PMID:12391016 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
abdominal aorta aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Best3 bestrophin 3 IAGP MGI PMID:37203562 NCBI chr10:116,822,219...116,865,688
Ensembl chr10:116,822,219...116,860,945 		JBrowse link
G Klf15 Kruppel-like transcription factor 15 IAGP MGI PMID:20375365 NCBI chr 6:90,437,785...90,468,785
Ensembl chr 6:90,439,558...90,452,220 		JBrowse link
G Ldlr low density lipoprotein receptor IAGP MGI PMID:12690199 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 IAGP MGI PMID:12690199 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 IAGP MGI PMID:23144462 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370 		JBrowse link
aortic aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IAGP MGI PMID:16864727 PMID:19139386 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IAGP MGI PMID:1115218 PMID:3385878 PMID:4808708 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Best3 bestrophin 3 IAGP MGI PMID:37203562 NCBI chr10:116,822,219...116,865,688
Ensembl chr10:116,822,219...116,860,945 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IAGP MGI PMID:19139386 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Fbn1 fibrillin 1 IAGP MGI PMID:10097121 PMID:22772368 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Ldlr low density lipoprotein receptor IAGP MGI PMID:12690199 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lox lysyl oxidase IAGP MGI PMID:12417550 PMID:12473682 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 IAGP MGI PMID:12690199 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Mrtfb myocardin related transcription factor B IAGP MGI PMID:22899851 NCBI chr16:13,073,913...13,235,393
Ensembl chr16:13,074,345...13,235,393 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit IAGP MGI PMID:17293478 NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 IAGP MGI PMID:16864727 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting IAGP MGI PMID:15496422 NCBI chr17:24,767,657...24,815,457
Ensembl chr17:24,768,808...24,815,482 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 IAGP MGI PMID:22772368 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 IAGP MGI PMID:15364874 PMID:15680392 NCBI chr  X:20,736,405...20,740,976
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:26195802 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
aortic sinus aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IAGP MGI PMID:10683374 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Fbn1 fibrillin 1 IAGP MGI PMID:9326947 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell IAGP MGI PMID:10683374 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
ascending aorta aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 IAGP MGI PMID:23636094 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 IAGP MGI PMID:19855011 PMID:20019329 PMID:23636094 PMID:26178373 NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545 		JBrowse link
G Fbn1 fibrillin 1 IAGP MGI PMID:16407178 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit IAGP MGI PMID:25255451 NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I IAGP MGI PMID:24355923 NCBI chr 4:47,353,222...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II IAGP MGI PMID:24355923 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
atrial septal aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 IAGP MGI PMID:11073884 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
brain aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfb platelet derived growth factor, B polypeptide IAGP MGI PMID:15084468 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling IAGP MGI PMID:16155214 NCBI chr19:46,385,335...46,477,243
Ensembl chr19:46,385,335...46,477,243 		JBrowse link
coronary artery aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gipc1 GIPC PDZ domain containing family, member 1 IAGP MGI PMID:23897694 NCBI chr 8:84,376,037...84,391,418
Ensembl chr 8:84,379,306...84,391,323 		JBrowse link
G Gja1 gap junction protein, alpha 1 IAGP MGI PMID:15548583 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
heart right ventricle aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam19 ADAM metallopeptidase domain 19 IAGP MGI PMID:14673146 NCBI chr11:45,945,329...46,038,174
Ensembl chr11:45,946,819...46,038,170 		JBrowse link
interventricular septum membranous part aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 IAGP MGI PMID:24938781 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Prox1 prospero homeobox 1 IAGP MGI PMID:24938781 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
intracranial aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msx1 msh homeobox 1 IAGP MGI PMID:21693521 NCBI chr 5:37,977,835...37,981,929
Ensembl chr 5:37,977,829...37,981,927 		JBrowse link
G Msx2 msh homeobox 2 IAGP MGI PMID:21693521 NCBI chr13:53,620,917...53,626,816
Ensembl chr13:53,620,920...53,627,110 		JBrowse link
G Nphp3 nephronophthisis 3 (adolescent) IAGP MGI PMID:1883968 NCBI chr 9:103,879,743...103,921,010
Ensembl chr 9:103,879,743...103,921,017 		JBrowse link
G Tagln transgelin IAGP MGI PMID:21693521 NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356 		JBrowse link
kidney microaneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IAGP MGI PMID:12177238 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Jag1 jagged 1 IAGP MGI PMID:11861489 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564 		JBrowse link
G Lamc1 laminin, gamma 1 IAGP MGI PMID:12015298 NCBI chr 1:153,094,668...153,208,532
Ensembl chr 1:153,094,668...153,208,532 		JBrowse link
G Notch2 notch 2 IAGP MGI PMID:11171333 PMID:11861489 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide IAGP MGI PMID:7958863 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide IAGP MGI PMID:11239463 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
retina microaneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta-synthase IAGP MGI PMID:25016930 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase IAGP MGI PMID:32245241 NCBI chr 4:133,696,339...133,728,267
Ensembl chr 4:133,696,339...133,728,229 		JBrowse link
G Fat1 FAT atypical cadherin 1 IAGP MGI PMID:23785297 NCBI chr 8:45,386,137...45,505,294
Ensembl chr 8:45,388,484...45,505,294 		JBrowse link
G Pomgnt1 protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase IEA MGI NCBI chr 4:116,007,700...116,017,041
Ensembl chr 4:115,981,037...116,017,046 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II IAGP MGI PMID:25857227 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tspan12 tetraspanin 12 IAGP MGI PMID:19837033 NCBI chr 6:21,771,390...21,879,557
Ensembl chr 6:21,771,394...21,852,514 		JBrowse link
thoracic aorta aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E IAGP MGI PMID:19139386 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Best3 bestrophin 3 IAGP MGI PMID:37203562 NCBI chr10:116,822,219...116,865,688
Ensembl chr10:116,822,219...116,860,945 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IAGP MGI PMID:19139386 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Klf15 Kruppel-like transcription factor 15 IAGP MGI PMID:20375365 NCBI chr 6:90,437,785...90,468,785
Ensembl chr 6:90,439,558...90,452,220 		JBrowse link
ventricular aneurysm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jup junction plakoglobin IAGP MGI PMID:21880664 NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16532
    cardiovascular system phenotype 4054
      abnormal cardiovascular system morphology 3203
        aneurysm 55
          aortic aneurysm + 22
          atrial septal aneurysm 1
          brain aneurysm 2
          coronary artery aneurysm 2
          gastric microaneurysm 0
          intestinal microaneurysm 0
          intracranial aneurysm 4
          kidney microaneurysm 6
          pulmonary artery aneurysm 0
          renal artery aneurysm 0
          retina microaneurysm 6
          ventricular aneurysm + 4
paths to the root