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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal cardiomyocyte apoptosis
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Accession:MP:0003221 term browser browse the term
Definition:change in the timing or the number of cardiac muscle cells undergoing programmed cell death
Comment:Note that this is a generic term that applies to cardiomyocytes irrespective of the life stage of the organism, that is, regardless of whether cardiac muscle cells are still in the process of differentiation or terminally differentiated.
Synonyms:exact_synonym: abnormal cardiac muscle cell apoptosis


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decreased cardiomyocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased cardiomyocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubd ubiquitin D IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5418
    muscle phenotype 199
      abnormal muscle physiology 124
        abnormal cardiomyocyte apoptosis 6
          abnormal fetal cardiomyocyte apoptosis + 0
          abnormal myocardial fiber apoptosis + 0
          decreased cardiomyocyte apoptosis + 3
          increased cardiomyocyte apoptosis + 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5418
    cellular phenotype 187
      abnormal cell physiology 146
        abnormal cell death 53
          abnormal programmed cell death 42
            abnormal apoptosis 42
              abnormal cardiomyocyte apoptosis 6
                abnormal fetal cardiomyocyte apoptosis + 0
                abnormal myocardial fiber apoptosis + 0
                decreased cardiomyocyte apoptosis + 3
                increased cardiomyocyte apoptosis + 3
paths to the root