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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:increased susceptibility to ischemic brain injury
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Accession:MP:0003076 term browser browse the term
Definition:more severe response, such as increased incidence and/or size of necrotic tissue, to lack of adequate blood flow resulting from trauma or disease, to support the normal functioning of all or part of the brain compared to controls
Synonyms:exact_synonym: decreased resistance to ischaemic brain injury;   decreased resistance to ischemic brain injury;   increased CNS stroke;   increased susceptibility to ischaemic brain injury
 related_synonym: increased susceptibility to spontaneous CNS ischaemia;   increased susceptibility to spontaneous CNS ischemia
 alt_id: MP:0006081

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increased susceptibility to ischemic brain injury term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IDA RGD PMID:14502288 RGD:734740 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5380
    nervous system phenotype 362
      abnormal nervous system physiology 206
        abnormal response to CNS ischemic injury 18
          increased susceptibility to ischemic brain injury 9
            increased cerebral infarct size 3
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