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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:arthritis
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Accession:MP:0002993 term browser browse the term
Definition:autoimmune joint inflammation, marked by changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures



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arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank progressive ankylosis IAGP MGI PMID:10894769 NCBI chr15:27,466,763...27,594,995
Ensembl chr15:27,466,763...27,594,995
JBrowse link
G Bak1 BCL2-antagonist/killer 1 IAGP MGI PMID:16055554 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein IAGP MGI PMID:16055554 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:15781582 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 IEA MGI NCBI chr 7:65,759,240...65,823,546
Ensembl chr 7:65,759,263...65,823,546
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV IAGP MGI PMID:23754379 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:16964445 NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 IAGP MGI PMID:34965962 NCBI chr 8:25,021,908...25,066,430
Ensembl chr 8:25,021,908...25,066,349
JBrowse link
G Igk immunoglobulin kappa chain complex IAGP MGI PMID:24591372 NCBI chr 6:67,532,620...70,703,738 JBrowse link
G Itgb7 integrin beta 7 IAGP MGI PMID:18439426 NCBI chr15:102,124,429...102,141,840
Ensembl chr15:102,124,430...102,140,379
JBrowse link
G Jun jun proto-oncogene IAGP MGI PMID:16163348 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene IAGP MGI PMID:16163348 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:22491258 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IAGP MGI PMID:16287858 NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831
JBrowse link
G Mefv Mediterranean fever IAGP MGI PMID:21600797 NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) IAGP MGI PMID:10520996 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
JBrowse link
G Mmp2 matrix metallopeptidase 2 IAGP MGI PMID:17400654 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp3 matrix metallopeptidase 3 IAGP MGI PMID:9433876 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 IAGP MGI PMID:15882565 NCBI chr19:32,573,072...32,644,587
Ensembl chr19:32,573,190...32,644,587
JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:10485649 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278
JBrowse link
G Plat plasminogen activator, tissue IAGP MGI PMID:11891190 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Sod3 superoxide dismutase 3, extracellular IAGP MGI PMID:15529385 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Tia1 cytotoxic granule-associated RNA binding protein 1 IAGP MGI PMID:14769925 NCBI chr 6:86,381,001...86,410,387
Ensembl chr 6:86,381,201...86,410,387
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:15366373 PMID:16287858 PMID:18250193 PMID:18439426 PMID:29618659 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:15289505 PMID:18250193 PMID:33210082 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IAGP MGI PMID:29618659 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:14647385 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899
JBrowse link
G Zfp36 zinc finger protein 36 IAGP MGI PMID:8630730 PMID:14769925 PMID:22491258 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
JBrowse link
accelerated temporomandibular joint osteoarthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bgn biglycan IAGP MGI PMID:16006154 PMID:16612079 NCBI chr  X:72,527,207...72,539,542
Ensembl chr  X:72,527,208...72,539,539
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IAGP MGI PMID:16087873 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349
JBrowse link
G Fmod fibromodulin IAGP MGI PMID:16006154 PMID:16612079 NCBI chr 1:133,964,992...133,976,018
Ensembl chr 1:133,964,992...133,976,015
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:26195802 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
decreased susceptibility to induced arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IAGP MGI PMID:17510707 NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847
JBrowse link
G Adam8 a disintegrin and metallopeptidase domain 8 IAGP MGI PMID:19737139 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 IAGP MGI PMID:15800624 PMID:20036347 NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716
JBrowse link
G Aif1 allograft inflammatory factor 1 IAGP MGI PMID:23929822 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein IAGP MGI PMID:9091585 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
JBrowse link
G Bmx BMX non-receptor tyrosine kinase IAGP MGI PMID:21471444 NCBI chr  X:162,975,838...163,041,189
Ensembl chr  X:162,975,838...163,041,189
JBrowse link
G C3 complement component 3 IAGP MGI PMID:15048732 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Cd1d1 CD1d1 antigen IAGP MGI PMID:15958069 NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748
JBrowse link
G Cd276 CD276 antigen IAGP MGI PMID:26065426 NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:11762953 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd69 CD69 antigen IAGP MGI PMID:12882836 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:16651620 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cfb complement factor B IAGP MGI PMID:15048732 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link
G Cfp complement factor properdin IAGP MGI PMID:20941861 NCBI chr  X:20,791,693...20,797,794
Ensembl chr  X:20,791,693...20,797,794
JBrowse link
G Clec5a C-type lectin domain family 5, member a IAGP MGI PMID:20212065 NCBI chr 6:40,551,832...40,562,739
Ensembl chr 6:40,551,828...40,562,755
JBrowse link
G Ctss cathepsin S IAGP MGI PMID:10072073 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IAGP MGI PMID:19109198 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IAGP MGI PMID:20939892 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Dgkz diacylglycerol kinase zeta IAGP MGI PMID:31801815 NCBI chr 2:91,763,167...91,806,788
Ensembl chr 2:91,763,169...91,806,209
JBrowse link
G Dusp2 dual specificity phosphatase 2 IAGP MGI PMID:16474395 NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
JBrowse link
G F2 coagulation factor II IAGP MGI PMID:21436072 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F2rl1 F2R like trypsin receptor 1 IAGP MGI PMID:12511586 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735
JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I IAGP MGI PMID:11911824 NCBI chr 3:96,190,225...96,201,285
Ensembl chr 3:96,190,225...96,201,285
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III IAGP MGI PMID:12528127 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV IAGP MGI PMID:20974962 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Gpsm3 G-protein signalling modulator 3 (AGS3-like, C. elegans) IAGP MGI PMID:23280397 NCBI chr17:34,808,780...34,810,728
Ensembl chr17:34,808,780...34,810,728
JBrowse link
G Hc hemolytic complement IAGP MGI PMID:9485083 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit IAGP MGI PMID:12628185 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Il17a interleukin 17A IAGP MGI PMID:12721360 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:12133972 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:12721360 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:24012418 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9317154 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:22101159 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ksr1 kinase suppressor of ras 1 IAGP MGI PMID:17056543 NCBI chr11:78,904,266...79,037,357
Ensembl chr11:78,904,266...79,037,233
JBrowse link
G Lta lymphotoxin A IAGP MGI PMID:9834074 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 IAGP MGI PMID:16670336 PMID:20656922 NCBI chr14:56,002,154...56,005,951
Ensembl chr14:56,003,419...56,005,951
JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 IAGP MGI PMID:20656922 NCBI chr14:55,995,379...56,001,523
Ensembl chr14:55,998,885...56,002,595
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:12628185 PMID:20941861 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA MGI NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IEA MGI NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mmd monocyte to macrophage differentiation-associated IAGP MGI PMID:33421113 NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415
JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:19364840 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:19218085 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Ndst2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 IAGP MGI PMID:19109198 NCBI chr14:20,773,798...20,784,638
Ensembl chr14:20,773,798...20,784,630
JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta IAGP MGI PMID:20740013 NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IAGP MGI PMID:19218085 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Panx3 pannexin 3 IAGP MGI PMID:26138248 NCBI chr 9:37,571,198...37,580,518
Ensembl chr 9:37,571,198...37,580,531
JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IAGP MGI PMID:19218085 NCBI chr 7:18,618,615...18,624,363
Ensembl chr 7:18,605,256...18,624,384
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 IAGP MGI PMID:19218085 NCBI chr17:32,631,433...32,643,157
Ensembl chr17:32,631,433...32,643,141
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IAGP MGI PMID:18412166 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:18412166 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Pla1a phospholipase A1 member A IAGP MGI PMID:35955693 NCBI chr16:38,214,245...38,253,553
Ensembl chr16:38,216,479...38,253,507
JBrowse link
G Plau plasminogen activator, urokinase IAGP MGI PMID:11891190 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plcg2 phospholipase C, gamma 2 IAGP MGI PMID:20111715 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) IAGP MGI PMID:12208866 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IAGP MGI PMID:16556900 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP MGI PMID:16556900 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 IAGP MGI PMID:22511759 NCBI chr 7:28,834,358...28,853,386
Ensembl chr 7:28,834,276...28,853,386
JBrowse link
G Syvn1 synovial apoptosis inhibitor 1, synoviolin IAGP MGI PMID:12975321 NCBI chr19:6,096,586...6,103,748
Ensembl chr19:6,096,606...6,103,742
JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 IAGP MGI PMID:33397982 NCBI chr 7:3,535,015...3,551,159
Ensembl chr 7:3,535,016...3,551,140
JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:19218085 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:9834074 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:12133972 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IAGP MGI PMID:12133972 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13 IAGP MGI PMID:19016524 NCBI chr11:69,573,403...69,576,380
Ensembl chr11:69,573,672...69,576,610
JBrowse link
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 IAGP MGI PMID:24140642 NCBI chr 4:63,642,837...63,663,296
Ensembl chr 4:63,642,840...63,663,350
JBrowse link
G Tpsab1 tryptase alpha/beta 1 IAGP MGI PMID:19109198 NCBI chr17:25,562,219...25,564,536
Ensembl chr17:25,562,212...25,564,541
JBrowse link
G Tpsb2 tryptase beta 2 IAGP MGI PMID:19109198 NCBI chr17:25,585,282...25,587,070
Ensembl chr17:25,585,170...25,588,079
JBrowse link
G Tyk2 tyrosine kinase 2 IAGP MGI PMID:11313413 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein IAGP MGI PMID:20212065 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:19841086 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899
JBrowse link
G Zfp36 zinc finger protein 36 IAGP MGI PMID:26831084 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
JBrowse link
increased susceptibility to induced arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash1l ASH1 like histone lysine methyltransferase IAGP MGI PMID:24012418 NCBI chr 3:88,857,721...88,986,682
Ensembl chr 3:88,857,929...88,986,682
JBrowse link
G C1qtnf3 C1q and tumor necrosis factor related protein 3 IAGP MGI PMID:24269820 NCBI chr15:10,952,418...10,980,248
Ensembl chr15:10,952,418...10,980,236
JBrowse link
G C1qtnf6 C1q and tumor necrosis factor related protein 6 IAGP MGI PMID:26404464 NCBI chr15:78,407,546...78,416,370
Ensembl chr15:78,407,546...78,415,616
JBrowse link
G Cd200 CD200 molecule IAGP MGI PMID:11099416 NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416
JBrowse link
G Cd274 CD274 antigen IAGP MGI PMID:21061440 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:15596723 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd59a CD59a antigen IAGP MGI PMID:15457473 NCBI chr 2:103,926,177...103,945,755
Ensembl chr 2:103,926,146...103,945,699
JBrowse link
G Clec4a2 C-type lectin domain family 4, member a2 IAGP MGI PMID:18204462 NCBI chr 6:123,099,627...123,119,891
Ensembl chr 6:123,083,387...123,120,958
JBrowse link
G Cry1 cryptochrome circadian regulator 1 IAGP MGI PMID:20042581 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Cry2 cryptochrome circadian regulator 2 IAGP MGI PMID:20042581 NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388
JBrowse link
G Cytl1 cytokine-like 1 IAGP MGI PMID:21652695 NCBI chr 5:37,892,863...37,897,164
Ensembl chr 5:37,892,863...37,897,164
JBrowse link
G Dicer1 dicer 1, ribonuclease type III IAGP MGI PMID:22179202 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211
JBrowse link
G Dusp1 dual specificity phosphatase 1 IAGP MGI PMID:16424221 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Edil3 EGF-like repeats and discoidin I-like domains 3 IAGP MGI PMID:27505251 NCBI chr13:88,969,591...89,471,344
Ensembl chr13:88,969,591...89,471,342
JBrowse link
G Erg ETS transcription factor IAGP MGI PMID:26097038 NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IAGP MGI PMID:12528127 PMID:21724994 PMID:23109709 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G Ffar2 free fatty acid receptor 2 IAGP MGI PMID:19865172 NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200
JBrowse link
G Foxn1 forkhead box N1 IAGP MGI PMID:22179202 NCBI chr11:78,248,403...78,277,597
Ensembl chr11:78,248,403...78,277,384
JBrowse link
G Fpr2 formyl peptide receptor 2 IAGP MGI PMID:20107188 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214
JBrowse link
G Hc hemolytic complement IAGP MGI PMID:9485083 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:9164973 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Ighm immunoglobulin heavy constant mu IAGP MGI PMID:20111715 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350
JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:11994477 PMID:37315560 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:20112392 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:19620301 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
JBrowse link
G Il6 interleukin 6 IAGP MGI PMID:24012418 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:19109195 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 IAGP MGI PMID:18282810 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:20112392 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mir140 microRNA 140 IAGP MGI PMID:20466812 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945
JBrowse link
G Myl3 myosin, light polypeptide 3 IAGP MGI PMID:37794006 NCBI chr 9:110,592,746...110,598,870
Ensembl chr 9:110,570,929...110,598,866
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 IAGP MGI PMID:15310853 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Nudt7 nudix hydrolase 7 IAGP MGI PMID:30143643 NCBI chr 8:114,860,314...114,881,471
Ensembl chr 8:114,860,297...114,881,479
JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 IAGP MGI PMID:14613294 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IAGP MGI PMID:19218085 NCBI chr 7:18,618,615...18,624,363
Ensembl chr 7:18,605,256...18,624,384
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma IAGP MGI PMID:10549291 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Selp selectin, platelet IAGP MGI PMID:10453030 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Socs3 suppressor of cytokine signaling 3 IAGP MGI PMID:17510322 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod3 superoxide dismutase 3, extracellular IAGP MGI PMID:15529385 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:15684036 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tmem178 transmembrane protein 178 IAGP MGI PMID:26644563 NCBI chr17:81,252,061...81,309,245
Ensembl chr17:81,252,061...81,309,245
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 IAGP MGI PMID:12577054 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:19841086 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899
JBrowse link
osteoarthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 IAGP MGI PMID:15800625 NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide IAGP MGI PMID:8895222 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Bgn biglycan IAGP MGI PMID:11978731 PMID:19932218 NCBI chr  X:72,527,207...72,539,542
Ensembl chr  X:72,527,208...72,539,539
JBrowse link
G Bmp7 bone morphogenetic protein 7 IAGP MGI PMID:25889639 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
JBrowse link
G Bmpr1a bone morphogenetic protein receptor, type 1A IAGP MGI PMID:15492776 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298
JBrowse link
G Col11a1 collagen, type XI, alpha 1 IAGP MGI PMID:13130470 NCBI chr 3:113,823,933...114,014,405
Ensembl chr 3:113,824,189...114,014,367
JBrowse link
G Col2a1 collagen, type II, alpha 1 IAGP MGI PMID:11680679 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576
JBrowse link
G Col9a1 collagen, type IX, alpha 1 IAGP MGI PMID:8197187 PMID:11680679 NCBI chr 1:24,216,670...24,291,819
Ensembl chr 1:24,216,691...24,291,765
JBrowse link
G Comp cartilage oligomeric matrix protein IAGP MGI PMID:17588960 NCBI chr 8:70,826,186...70,834,721
Ensembl chr 8:70,826,208...70,834,716
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IAGP MGI PMID:7344126 PMID:8055108 NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
JBrowse link
G Epyc epiphycan IAGP MGI PMID:19932218 NCBI chr10:97,479,930...97,517,770
Ensembl chr10:97,479,930...97,518,316
JBrowse link
G Erg ETS transcription factor IAGP MGI PMID:26097038 NCBI chr16:95,160,028...95,387,452
Ensembl chr16:95,160,028...95,387,452
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IAGP MGI PMID:16087873 PMID:24550287 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349
JBrowse link
G Fmod fibromodulin IAGP MGI PMID:11978731 PMID:12089156 NCBI chr 1:133,964,992...133,976,018
Ensembl chr 1:133,964,992...133,976,015
JBrowse link
G Hspg2 perlecan (heparan sulfate proteoglycan 2) IAGP MGI PMID:17213231 NCBI chr 4:137,196,062...137,297,941
Ensembl chr 4:137,196,080...137,297,941
JBrowse link
G Hyal1 hyaluronoglucosaminidase 1 IAGP MGI PMID:18344557 NCBI chr 9:107,454,149...107,458,898
Ensembl chr 9:107,454,126...107,458,909
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 IAGP MGI PMID:11790802 PMID:12379497 NCBI chr19:5,790,928...5,808,564
Ensembl chr19:5,790,932...5,808,560
JBrowse link
G Lum lumican IAGP MGI PMID:12089156 NCBI chr10:97,401,363...97,408,565
Ensembl chr10:97,400,990...97,408,565
JBrowse link
G Matn3 matrilin 3 IAGP MGI PMID:16877353 NCBI chr12:8,997,929...9,022,028
Ensembl chr12:8,997,929...9,022,028
JBrowse link
G Mir140 microRNA 140 IAGP MGI PMID:20466812 NCBI chr 8:108,277,876...108,277,945
Ensembl chr 8:108,277,876...108,277,945
JBrowse link
G Mmp3 matrix metallopeptidase 3 IAGP MGI PMID:9433876 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Myl3 myosin, light polypeptide 3 IAGP MGI PMID:37794006 NCBI chr 9:110,592,746...110,598,870
Ensembl chr 9:110,570,929...110,598,866
JBrowse link
G Nid2 nidogen 2 IAGP MGI PMID:26683663 NCBI chr14:19,801,325...19,861,855
Ensembl chr14:19,801,333...19,861,855
JBrowse link
G Nudt7 nudix hydrolase 7 IAGP MGI PMID:30143643 NCBI chr 8:114,860,314...114,881,471
Ensembl chr 8:114,860,297...114,881,479
JBrowse link
G Pbxip1 pre B cell leukemia transcription factor interacting protein 1 IAGP MGI PMID:30659184 NCBI chr 3:89,343,982...89,358,259
Ensembl chr 3:89,344,013...89,358,259
JBrowse link
G Plcg2 phospholipase C, gamma 2 IAGP MGI PMID:15845450 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:15845450 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:16087873 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
JBrowse link
G Smad2 SMAD family member 2 IAGP MGI PMID:15630024 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:11285272 PMID:15630024 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I IAGP MGI PMID:28716756 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
rheumatoid arthritis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 IAGP MGI PMID:26114879 NCBI chr 1:173,177,105...173,293,606
Ensembl chr 1:173,178,445...173,293,606
JBrowse link
G Dnase2a deoxyribonuclease II alpha IAGP MGI PMID:17066036 PMID:26114879 NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:17066036 PMID:26114879 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Il17a interleukin 17A IAGP MGI PMID:19144317 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il17f interleukin 17F IAGP MGI PMID:19144317 NCBI chr 1:20,847,370...20,855,498
Ensembl chr 1:20,847,370...20,860,841
JBrowse link
G Il1rn interleukin 1 receptor antagonist IAGP MGI PMID:15086551 PMID:19144317 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il6st interleukin 6 signal transducer IAGP MGI PMID:12370259 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:18390736 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 IAGP MGI PMID:15310853 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) IAGP MGI PMID:12208866 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:7840851 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677
JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:10204494 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
JBrowse link
G Tnf tumor necrosis factor IAGP MGI PMID:10204494 PMID:26195802 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IAGP MGI PMID:10204494 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP MGI PMID:14647385 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16659
    skeleton phenotype 3335
      abnormal skeleton physiology 843
        abnormal joint physiology 226
          joint inflammation 209
            arthritis 197
              decreased susceptibility to induced arthritis 87
              increased susceptibility to induced arthritis 70
              osteoarthritis + 32
              rheumatoid arthritis 16
Path 2
Term Annotations click to browse term
  mammalian phenotype 16659
    immune system phenotype 5592
      abnormal immune system physiology 3404
        abnormal inflammatory response 1762
          increased inflammatory response 1510
            joint inflammation 209
              arthritis 197
                decreased susceptibility to induced arthritis 87
                increased susceptibility to induced arthritis 70
                osteoarthritis + 32
                rheumatoid arthritis 16
paths to the root