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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased urine protein level
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Accession:MP:0002962 term browser browse the term
Definition:greater than the normal amount of proteins in the urine
Synonyms:exact_synonym: increased protein excretion
 related_synonym: proteinuria
 alt_id: MP:0005160
 xref: HP:0000093


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increased urine protein level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IAGP DNA:missense mutation:cds:p.L111F RGD PMID:18064521 RGD:2292230 NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711 		JBrowse link
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP As compared to SS parents RGD PMID:23185005 RGD:9685162 NCBI chr 1:34,258,899...34,388,952
Ensembl chr 1:34,258,899...34,388,952 		JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP As compared to SS parents RGD PMID:23185005 RGD:9685162
G Agtrap angiotensin II receptor-associated protein IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,790,565...163,802,174
Ensembl chr 5:163,791,887...163,802,174 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661 		JBrowse link
G Lepr leptin receptor IMP
IAGP 		DNA:mutations:cds: : (rat) RGD PMID:27465994 PMID:10901178 RGD:12911217, RGD:401965414 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:27465994 RGD:12911217
G Mthfr methylenetetrahydrofolate reductase IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 IMP DNA:deletion:exon1:heterozygous 107 bp deletion RGD PMID:26888427 RGD:11040458 NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419 		JBrowse link
G Ndufc2em2Mcwi NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26888427 RGD:11040458
G Nppb natriuretic peptide B IMP RGD PMID:26063669 RGD:12910116 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nppbem2Mcwi natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26063669 RGD:12910116
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110 		JBrowse link
G Rab38 RAB38, member RAS oncogene family IAGP compared to FHH-Tg(CAG-Rab38)1Mcwi, FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi RGD PMID:23291471 RGD:13782139 NCBI chr 1:151,595,153...151,675,492
Ensembl chr 1:151,595,078...151,675,493 		JBrowse link
G Rab38em1Mcwi RAB38, member RAS oncogene family; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IAGP compared to FHH-Tg(CAG-Rab38)1Mcwi, FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi RGD PMID:23291471 RGD:13782139
G Resp18 regulated endocrine-specific protein 18 IMP RGD PMID:29570433 RGD:14348960 NCBI chr 9:84,213,844...84,220,186
Ensembl chr 9:84,213,467...84,221,299 		JBrowse link
G Resp18em2Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:29570433 RGD:14348960
G Tmem67 transmembrane protein 67 IAGP RGD PMID:11095650 RGD:1300514 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:30,333,793...30,386,666 		JBrowse link
albuminuria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btg2 BTG anti-proliferation factor 2 IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690 		JBrowse link
G Chi3l1 chitinase 3 like 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Chit1 chitinase 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,117,886...48,165,645
Ensembl chr13:48,145,893...48,165,639 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661 		JBrowse link
G Etnk2 ethanolamine kinase 2 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:47,362,964...47,381,100
Ensembl chr13:47,363,060...47,381,100 		JBrowse link
G Fmod fibromodulin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,150,355...49,157,204
Ensembl chr13:49,150,359...49,157,204 		JBrowse link
G Ipo9 importin 9 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,362,244...49,414,477
Ensembl chr13:49,365,716...49,414,477 		JBrowse link
G Lepr leptin receptor sexual_dimorphism
treatment 		IAGP compared to BN
compared to ad lib fed rats 		RGD PMID:20159938 PMID:11500530 RGD:7365117, RGD:628581 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Leprfa leptin receptor; fa mutant sexual_dimorphism
treatment 		IAGP compared to BN
compared to ad lib fed rats 		RGD PMID:20159938 PMID:11500530 RGD:7365117, RGD:628581
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,976,193...49,095,870
Ensembl chr13:48,976,193...49,095,857 		JBrowse link
G Mybph myosin binding protein H IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,205,162...48,212,928
Ensembl chr13:48,205,269...48,212,928 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IMP RGD PMID:24722447 RGD:12910103 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041 		JBrowse link
G Optc opticin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:47,906,145...47,920,334
Ensembl chr13:47,906,197...47,917,416 		JBrowse link
G Plekha6 pleckstrin homology domain containing A6 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:47,166,899...47,307,003
Ensembl chr13:47,167,160...47,307,003 		JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324 		JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,099,922...49,120,247
Ensembl chr13:49,099,925...49,120,121 		JBrowse link
G Ren renin IAGP RGD PMID:23817491 RGD:12802368 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Rnpep arginyl aminopeptidase IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:49,251,259...49,271,440
Ensembl chr13:49,251,264...49,269,799 		JBrowse link
G Sox13 SRY-box transcription factor 13 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:47,383,145...47,427,572
Ensembl chr13:47,383,145...47,435,663 		JBrowse link
G Syt2 synaptotagmin 2 IAGP RGD PMID:23460292 RGD:12802369 NCBI chr13:48,639,634...48,749,814
Ensembl chr13:48,639,934...48,749,812 		JBrowse link
increased urine microalbumin level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP DNA:mutations:cds: : (rat) RGD PMID:30278832 PMID:28746409 RGD:401960095, RGD:401965413 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 induces IMP compared to vehicle-treated control RGD PMID:29923767 RGD:149735534 NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:14,043,877...14,149,304 		JBrowse link
G Trpc6em1Mcwi transient receptor potential cation channel, subfamily C, member 6; CRISPR/Cas9 induced mutant 1, Medical College of Wisconsin induces IMP compared to vehicle-treated control RGD PMID:29923767 RGD:149735534
increased urine microglobulin level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5440
    renal/urinary system phenotype 652
      abnormal renal/urinary system physiology 481
        abnormal urine homeostasis 383
          abnormal urine protein level 320
            increased urine protein level 213
              albuminuria 91
              bilirubinuria 0
              hemoglobinuria 0
              increased urine major urinary protein level 0
              increased urine microalbumin level 24
              increased urine microglobulin level + 1
              myoglobinuria 0
paths to the root