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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased systemic arterial blood pressure
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Accession:MP:0002843 term browser browse the term
Definition:decreased tension of the blood within the systemic arteries
Synonyms:exact_synonym: low blood pressure;   reduced blood pressure


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decreased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IAGP DNA:polymorphism RGD PMID:19423552 RGD:2312639 NCBI chr 1:32,430,436...32,562,481
Ensembl chr 1:32,430,436...32,560,494 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:12215473 RGD:1580453 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:24935944 RGD:14985214 NCBI chr12:40,001,205...40,030,671
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204 NCBI chr10:96,489,329...96,520,745
Ensembl chr10:95,960,725...96,021,702 		JBrowse link
G Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204
decreased mean systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Cd247 Cd247 molecule induced IMP compared to wild-type RGD PMID:24343121 PMID:24343121 RGD:13442481, RGD:13442481 NCBI chr13:80,576,264...80,651,422
Ensembl chr13:78,043,307...78,122,263 		JBrowse link
G Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin induced IMP compared to wild-type RGD PMID:24343121 PMID:24343121 RGD:13442481, RGD:13442481
G Cd36 CD36 molecule IMP RGD PMID:22128087 RGD:6893560 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Clcn6 chloride voltage-gated channel 6 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:158,434,299...158,465,059 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:24935944 RGD:14985214 NCBI chr12:40,001,205...40,030,671
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Mc4r melanocortin 4 receptor IMP RGD PMID:24400148 RGD:13825242 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:24400148 RGD:13825242
G Nox4 NADPH oxidase 4 induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nox4em2Mcwi NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830
G P2rx7 purinergic receptor P2X 7 IMP RGD PMID:31630543 RGD:14995937 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Ren renin sexual_dimorphism IMP compared to wild type
compared to wild type male		 RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin sexual_dimorphism IMP compared to wild type
compared to wild type male		 RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614
decreased systemic arterial diastolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP As compared to SS parents RGD PMID:23185005 RGD:9685162 NCBI chr 1:32,430,436...32,562,481
Ensembl chr 1:32,430,436...32,560,494 		JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP As compared to SS parents RGD PMID:23185005 RGD:9685162
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 IMP RGD PMID:31327268 RGD:18899561 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600 		JBrowse link
G Camk2n1em1Tja calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja IMP RGD PMID:31327268 RGD:18899561
G Clcn6 chloride voltage-gated channel 6 IMP as compared to the wild-type RGD PMID:24006081 RGD:8662415 NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:158,434,299...158,465,059 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Ren renin sexual_dimorphism IMP compared to wild type
compared to wild type male		 RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin sexual_dimorphism IMP compared to wild type male RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614
decreased systemic arterial systolic blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP As compared to SS parents RGD PMID:23185005 RGD:9685162 NCBI chr 1:32,430,436...32,562,481
Ensembl chr 1:32,430,436...32,560,494 		JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP As compared to SS parents RGD PMID:23185005 RGD:9685162
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 IMP RGD PMID:31327268 RGD:18899561 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600 		JBrowse link
G Camk2n1em1Tja calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja IMP RGD PMID:31327268 RGD:18899561
G Cfb complement factor B IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfbem1Tja complement factor B, ZFN induced mutant 1, Tja IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403
G Gper1 G protein-coupled estrogen receptor 1 IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj IMP compared to wild type SS rat RGD PMID:30354811 RGD:39939000
G Rarres2 retinoic acid receptor responder 2 sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:77,522,535...77,525,556 		JBrowse link
G Rarres2em1Msu retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu sexual_dimorphism IMP compared to female wild-type RGD PMID:29906243 PMID:29906243 RGD:38596340, RGD:38596340
G Ren renin sexual_dimorphism IMP compared to wild type
compared to wild type male		 RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin sexual_dimorphism IMP compared to wild type male RGD PMID:21242461 PMID:21242461 RGD:7771614, RGD:7771614
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Term Annotations click to browse term
  mammalian phenotype 5428
    cardiovascular system phenotype 1374
      abnormal cardiovascular system physiology 1152
        abnormal systemic arterial blood pressure 998
          decreased systemic arterial blood pressure 392
            decreased mean systemic arterial blood pressure 157
            decreased systemic arterial diastolic blood pressure 63
            decreased systemic arterial systolic blood pressure 192
            hypotension 0
paths to the root