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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating aldosterone level
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Accession:MP:0002667 term browser browse the term
Definition:decreased in the blood concentration of the hormone that is secreted by the adrenal cortex and regulates sodium conservation and potassium secretion in the distal renal tubule
Synonyms:exact_synonym: hypoaldosteronism;   reduced circulating aldosterone level
 narrow_synonym: decreased serum aldosterone level;   decreased serum levels of aldosterone



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decreased circulating aldosterone level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfb complement factor B IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740
JBrowse link
G Cfbem1Tja complement factor B, ZFN induced mutant 1, Tja IMP compared to wild type SHR RGD PMID:28739975 RGD:127285403
G Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204 NCBI chr10:96,489,329...96,520,745
Ensembl chr10:96,460,331...96,566,075
JBrowse link
G Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:28931751 RGD:38500204

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5432
    homeostasis/metabolism phenotype 1429
      abnormal homeostasis 1330
        abnormal hormone level 324
          abnormal aldosterone level 12
            abnormal circulating aldosterone level 11
              decreased circulating aldosterone level 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 5432
    homeostasis/metabolism phenotype 1429
      abnormal homeostasis 1330
        abnormal lipid homeostasis 364
          abnormal lipid level 359
            abnormal circulating lipid level 310
              abnormal circulating mineralocorticoid level 11
                decreased circulating mineralocorticoid level 6
                  decreased circulating aldosterone level 6
paths to the root