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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:reduced sensorimotor gating
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Accession:MP:0002635 term browser browse the term
Definition:attenuation of the process by which inhibitory neural pathways filter multiple stimuli and allow attention to be focused on one stimulus; usually measured by pre-pulse inhibition (PPI)
Synonyms:exact_synonym: impaired sensorimotor gating

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reduced sensorimotor gating term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp13a5 ATPase type 13A5 IEA MGI NCBI chr16:29,049,242...29,208,807
Ensembl chr16:29,050,603...29,197,550
JBrowse link
G Ccdc88a coiled coil domain containing 88A IAGP MGI PMID:25378165 NCBI chr11:29,323,521...29,460,808
Ensembl chr11:29,323,658...29,460,808
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 IAGP MGI PMID:9298901 NCBI chr 4:155,931,829...155,943,760
Ensembl chr 4:155,931,859...155,943,760
JBrowse link
G Fzd3 frizzled class receptor 3 IAGP MGI PMID:21746835 NCBI chr14:65,429,890...65,499,912
Ensembl chr14:65,429,898...65,499,912
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 IEA MGI NCBI chr14:30,723,137...30,733,948
Ensembl chr14:30,723,357...30,733,948
JBrowse link
G Nrg3 neuregulin 3 IAGP MGI PMID:27606322 NCBI chr14:38,086,093...39,195,045
Ensembl chr14:38,090,909...39,195,045
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide IAGP MGI PMID:25803852 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Pomk protein-O-mannose kinase IAGP MGI PMID:21746835 NCBI chr 8:26,470,632...26,484,149
Ensembl chr 8:26,470,632...26,484,161
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) IAGP MGI PMID:12851457 NCBI chr11:17,109,298...17,150,380
Ensembl chr11:17,109,263...17,150,375
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16675393 PMID:19208814 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Setd1a SET domain containing 1A IAGP MGI PMID:35245111 NCBI chr 7:127,376,561...127,399,294
Ensembl chr 7:127,375,842...127,399,294
JBrowse link
G Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 IAGP MGI PMID:23922840 NCBI chr 6:114,259,735...114,294,491
Ensembl chr 6:114,259,596...114,294,493
JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 IAGP MGI PMID:19208814 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
JBrowse link
G Sp4 trans-acting transcription factor 4 IAGP MGI PMID:15558077 NCBI chr12:118,195,421...118,265,211
Ensembl chr12:118,198,668...118,265,175
JBrowse link
G Tmem108 transmembrane protein 108 IAGP MGI PMID:28096412 NCBI chr 9:103,360,135...103,639,099
Ensembl chr 9:103,360,146...103,639,036
JBrowse link
G Tmem198b transmembrane protein 198b IEA MGI NCBI chr10:128,633,958...128,641,255
Ensembl chr10:128,635,905...128,640,239
JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein IAGP MGI PMID:12569157 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 16476
    nervous system phenotype 4511
      abnormal nervous system physiology 2623
        abnormal sensorimotor gating 30
          reduced sensorimotor gating 17
paths to the root