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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal plasma cell morphology
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Accession:MP:0002439 term browser browse the term
Definition:any structural anomaly of a terminally differentiated, post-mitotic, short-lived cell of the B cell lineage devoted to producing large amounts of immunoglobulin
Comment:Plasma cells are terminally differentiated B cells and no longer respond to antigens or helper T cells. In addition, they no longer express surface Ig or surface MHC class II molecules, and they secrete antibody at high rates.
Synonyms:exact_synonym: abnormal plasmacyte morphology;   plasma cell abnormalities



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  mammalian phenotype 5417
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal leukocyte morphology 154
            abnormal mononuclear cell morphology 127
              abnormal lymphocyte morphology 99
                abnormal B cell morphology 29
                  abnormal plasma cell morphology 0
                    abnormal long lived plasma cell morphology 0
                    abnormal plasma cell differentiation 0
                    abnormal plasma cell number + 0
                    abnormal short lived plasma cell morphology 0
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