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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal basophil morphology
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Accession:MP:0002422 term browser browse the term
Definition:any structural anomaly of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size; these cells contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation
Synonyms:exact_synonym: basophil abnormalities


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decreased basophil cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ablim3 actin binding LIM protein family, member 3 IEA MGI NCBI chr18:61,932,463...62,044,956
Ensembl chr18:61,932,463...62,044,895 		JBrowse link
G Blnk B cell linker IEA MGI NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 IAGP MGI PMID:21799179 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:11970874 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Chmp4c charged multivesicular body protein 4C IEA MGI NCBI chr 3:10,432,033...10,456,065
Ensembl chr 3:10,431,967...10,493,916 		JBrowse link
G Col4a3 collagen, type IV, alpha 3 IEA MGI NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780 		JBrowse link
G Cpa3 carboxypeptidase A3, mast cell IAGP MGI PMID:22101159 NCBI chr 3:20,269,780...20,296,373
Ensembl chr 3:20,269,784...20,296,345 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha IAGP MGI PMID:11970874 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 IAGP MGI PMID:17923703 NCBI chr18:24,338,401...24,419,873
Ensembl chr18:24,338,401...24,419,875 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble IEA MGI NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Il21r interleukin 21 receptor IAGP MGI PMID:17077330 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:22326582 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Kiss1r KISS1 receptor IAGP MGI PMID:22067321 NCBI chr10:79,752,786...79,759,922
Ensembl chr10:79,752,805...79,758,107 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:22101159 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:22001390 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mcpt8 mast cell protease 8 IAGP MGI PMID:20664169 NCBI chr14:56,319,620...56,322,951
Ensembl chr14:56,319,623...56,322,730 		JBrowse link
G Pard3 par-3 family cell polarity regulator IEA MGI NCBI chr 8:127,790,131...128,338,767
Ensembl chr 8:127,790,643...128,338,767 		JBrowse link
G Pcdhb13 protocadherin beta 13 IEA MGI NCBI chr18:37,575,570...37,579,262
Ensembl chr18:37,575,553...37,579,262 		JBrowse link
G Tbk1 TANK-binding kinase 1 IAGP MGI PMID:20651301 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B IEA MGI NCBI chr11:51,875,965...51,894,972
Ensembl chr11:51,876,324...51,891,589 		JBrowse link
increased basophil cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial IEA MGI NCBI chr17:45,817,473...45,831,769
Ensembl chr17:45,817,767...45,831,769 		JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 IEA MGI NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231 		JBrowse link
G Abhd10 abhydrolase domain containing 10 IEA MGI NCBI chr16:45,550,088...45,563,355
Ensembl chr16:45,550,088...45,563,318 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 IEA MGI NCBI chr 7:119,216,980...119,261,738
Ensembl chr 7:119,206,249...119,261,738 		JBrowse link
G Ahcy S-adenosylhomocysteine hydrolase IEA MGI NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417 		JBrowse link
G Alg1 ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase IEA MGI NCBI chr16:5,051,410...5,062,773
Ensembl chr16:5,051,485...5,062,776 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase IAGP MGI PMID:17043146 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
G Art1 ADP-ribosyltransferase 1 IEA MGI NCBI chr 7:101,750,913...101,771,410
Ensembl chr 7:101,750,950...101,763,140 		JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase IEA MGI NCBI chr 3:88,857,721...88,986,682
Ensembl chr 3:88,857,929...88,986,682 		JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain 1A IEA MGI NCBI chr12:54,939,774...55,061,155
Ensembl chr12:54,939,774...55,061,133 		JBrowse link
G Bcar3 breast cancer anti-estrogen resistance 3 IEA MGI NCBI chr 3:122,213,406...122,323,840
Ensembl chr 3:122,087,785...122,323,840 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated IEA MGI NCBI chr16:44,305,408...44,379,233
Ensembl chr16:44,305,412...44,379,260 		JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 IEA MGI NCBI chr11:31,615,150...31,621,862
Ensembl chr11:31,615,181...31,621,885 		JBrowse link
G Bok BCL2-related ovarian killer IEA MGI NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486 		JBrowse link
G Cd1d1 CD1d1 antigen IEA MGI NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748 		JBrowse link
G Cdc42ep5 CDC42 effector protein 5 IEA MGI NCBI chr 7:4,154,259...4,167,830
Ensembl chr 7:4,154,259...4,167,859 		JBrowse link
G Cib2 calcium and integrin binding family member 2 IEA MGI NCBI chr 9:54,452,074...54,467,512
Ensembl chr 9:54,452,078...54,467,502 		JBrowse link
G Clcnkb chloride channel, voltage-sensitive Kb IEA MGI NCBI chr 4:141,131,668...141,143,440
Ensembl chr 4:141,131,664...141,143,325 		JBrowse link
G Cldn9 claudin 9 IEA MGI NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000 		JBrowse link
G Clstn1 calsyntenin 1 IEA MGI NCBI chr 4:149,670,536...149,733,356
Ensembl chr 4:149,670,925...149,733,356 		JBrowse link
G Col17a1 collagen, type XVII, alpha 1 IAGP MGI PMID:25310407 NCBI chr19:47,634,783...47,680,460
Ensembl chr19:47,634,783...47,680,533 		JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 IEA MGI NCBI chr 8:123,202,882...123,209,831
Ensembl chr 8:123,202,882...123,210,877 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 IEA MGI NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927 		JBrowse link
G Eddm3b epididymal protein 3B IEA MGI NCBI chr14:51,351,886...51,355,248
Ensembl chr14:51,351,883...51,355,264 		JBrowse link
G Emc4 ER membrane protein complex subunit 4 IEA MGI NCBI chr 2:112,193,349...112,209,532
Ensembl chr 2:112,193,356...112,198,372 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 IAGP MGI PMID:25692702 NCBI chr10:24,649,712...24,712,093
Ensembl chr10:24,648,304...24,718,721 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor IEA MGI NCBI chr18:77,981,618...78,080,539
Ensembl chr18:77,981,680...78,078,228 		JBrowse link
G Fancl Fanconi anemia, complementation group L IEA MGI NCBI chr11:26,337,084...26,421,883
Ensembl chr11:26,336,135...26,421,876 		JBrowse link
G Fbxl18 F-box and leucine-rich repeat protein 18 IEA MGI NCBI chr 5:142,852,701...142,882,696
Ensembl chr 5:142,852,701...142,881,176 		JBrowse link
G Fbxl19 F-box and leucine-rich repeat protein 19 IEA MGI NCBI chr 7:127,343,059...127,368,655
Ensembl chr 7:127,343,715...127,368,655 		JBrowse link
G Fbxo28 F-box protein 28 IEA MGI NCBI chr 1:182,140,667...182,169,171
Ensembl chr 1:182,140,667...182,169,194 		JBrowse link
G Fbxo36 F-box protein 36 IEA MGI NCBI chr 1:84,817,562...84,878,208
Ensembl chr 1:84,817,562...84,878,208 		JBrowse link
G Fbxo9 f-box protein 9 IEA MGI NCBI chr 9:77,988,781...78,016,347
Ensembl chr 9:77,988,781...78,016,347 		JBrowse link
G Fbxw2 F-box and WD-40 domain protein 2 IEA MGI NCBI chr 2:34,694,185...34,716,229
Ensembl chr 2:34,694,526...34,716,323 		JBrowse link
G Fbxw8 F-box and WD-40 domain protein 8 IEA MGI NCBI chr 5:118,203,046...118,293,523
Ensembl chr 5:118,203,030...118,293,529 		JBrowse link
G Gp9 glycoprotein 9 platelet IEA MGI NCBI chr 6:87,753,115...87,756,768
Ensembl chr 6:87,755,054...87,756,750 		JBrowse link
G Gprc5c G protein-coupled receptor, family C, group 5, member C IAGP MGI PMID:21840300 NCBI chr11:114,741,976...114,763,443
Ensembl chr11:114,741,978...114,763,443 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:26304963 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Has1 hyaluronan synthase 1 IEA MGI NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467 		JBrowse link
G Hddc2 HD domain containing 2 IEA MGI NCBI chr10:31,189,296...31,204,200
Ensembl chr10:31,189,379...31,204,200 		JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 IEA MGI NCBI chr12:51,790,504...51,876,540
Ensembl chr12:51,790,505...51,876,319 		JBrowse link
G Herc4 hect domain and RLD 4 IEA MGI NCBI chr10:63,079,122...63,153,660
Ensembl chr10:63,079,589...63,153,657 		JBrowse link
G Herc6 hect domain and RLD 6 IEA MGI NCBI chr 6:57,557,977...57,642,121
Ensembl chr 6:57,557,985...57,641,617 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D IEA MGI NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797 		JBrowse link
G Hook3 hook microtubule tethering protein 3 IEA MGI NCBI chr 8:26,511,449...26,609,646
Ensembl chr 8:26,511,449...26,609,252 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) IAGP MGI PMID:20512127
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:7923373 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:20512127 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:8700894 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 IEA MGI NCBI chr 1:172,148,075...172,156,889
Ensembl chr 1:172,148,068...172,156,885 		JBrowse link
G Kcnk13 potassium channel, subfamily K, member 13 IEA MGI NCBI chr12:99,928,132...100,028,941
Ensembl chr12:99,930,758...100,028,941 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A IEA MGI NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:20512127 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Klk4 kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) IEA MGI NCBI chr 7:43,530,584...43,535,228
Ensembl chr 7:43,530,584...43,535,228 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:25359213 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lama4 laminin, alpha 4 IEA MGI NCBI chr10:38,841,511...38,986,184
Ensembl chr10:38,841,511...38,986,184 		JBrowse link
G Ldb3 LIM domain binding 3 IEA MGI NCBI chr14:34,248,656...34,312,276
Ensembl chr14:34,248,560...34,310,639 		JBrowse link
G Limd1 LIM domains containing 1 IEA MGI NCBI chr 9:123,306,790...123,350,617
Ensembl chr 9:123,307,771...123,350,617 		JBrowse link
G Lpin3 lipin 3 IEA MGI NCBI chr 2:160,722,590...160,747,920
Ensembl chr 2:160,722,590...160,747,922 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor IEA MGI NCBI chr 7:34,043,569...34,089,134
Ensembl chr 7:34,044,071...34,092,740 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:20512127 NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G Mmgt2 membrane magnesium transporter 2 IEA MGI NCBI chr11:62,538,999...62,557,185
Ensembl chr11:62,539,490...62,557,180 		JBrowse link
G Nexmif neurite extension and migration factor IEA MGI NCBI chr  X:103,120,367...103,245,403
Ensembl chr  X:103,121,040...103,244,791 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 IEA MGI NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007 		JBrowse link
G Nkg7 natural killer cell group 7 sequence IEA MGI NCBI chr 7:43,086,562...43,087,670
Ensembl chr 7:43,086,497...43,087,673 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell IEA MGI NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 IEA MGI NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469 		JBrowse link
G Otud6a OTU domain containing 6A IEA MGI NCBI chr  X:99,472,514...99,474,859
Ensembl chr  X:99,472,619...99,473,491 		JBrowse link
G Otud6b OTU domain containing 6B IEA MGI NCBI chr 4:14,809,503...14,826,413
Ensembl chr 4:14,809,498...14,826,587 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 IAGP MGI PMID:25692702 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Parp12 poly (ADP-ribose) polymerase family, member 12 IEA MGI NCBI chr 6:39,063,346...39,095,283
Ensembl chr 6:39,063,344...39,095,283 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 IEA MGI NCBI chr 1:130,616,780...130,656,990
Ensembl chr 1:130,616,919...130,656,990
Ensembl chr 1:130,616,919...130,656,990 		JBrowse link
G Phldb2 pleckstrin homology like domain, family B, member 2 IEA MGI NCBI chr16:45,566,593...45,773,961
Ensembl chr16:45,566,606...45,773,961 		JBrowse link
G Ramp1 receptor (calcitonin) activity modifying protein 1 IEA MGI NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918 		JBrowse link
G Rft1 RFT1 homolog IEA MGI NCBI chr14:30,375,041...30,413,274
Ensembl chr14:30,376,317...30,413,274 		JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B IEA MGI NCBI chr10:84,753,136...84,854,201
Ensembl chr10:84,753,480...84,854,201 		JBrowse link
G Sbno1 strawberry notch 1 IEA MGI NCBI chr 5:124,506,765...124,564,059
Ensembl chr 5:124,506,765...124,564,064 		JBrowse link
G Sirt1 sirtuin 1 IEA MGI NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 IEA MGI NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 IEA MGI NCBI chr12:81,073,582...81,233,188
Ensembl chr12:81,073,582...81,233,188 		JBrowse link
G Speg SPEG complex locus IEA MGI NCBI chr 1:75,351,931...75,408,964
Ensembl chr 1:75,351,941...75,408,964 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stra6l STRA6-like IEA MGI NCBI chr 4:45,818,940...45,887,010
Ensembl chr 4:45,848,664...45,887,008 		JBrowse link
G Tmem8b transmembrane protein 8B IEA MGI NCBI chr 4:43,668,971...43,692,668
Ensembl chr 4:43,668,971...43,692,668 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEA MGI NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 IEA MGI NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743 		JBrowse link
G Tra2a transformer 2 alpha IEA MGI NCBI chr 6:49,220,855...49,241,182
Ensembl chr 6:49,220,858...49,240,967 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 IEA MGI NCBI chr16:87,251,833...87,280,403
Ensembl chr16:87,251,591...87,280,405 		JBrowse link
G Zfp398 zinc finger protein 398 IEA MGI NCBI chr 6:47,812,567...47,850,476
Ensembl chr 6:47,812,595...47,850,471 		JBrowse link
G Zswim1 zinc finger SWIM-type containing 1 IEA MGI NCBI chr 2:164,664,933...164,668,791
Ensembl chr 2:164,664,606...164,668,791 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16476
    hematopoietic system phenotype 5344
      abnormal hematopoietic system morphology/development 4885
        abnormal bone marrow cell morphology/development 794
          abnormal myeloblast morphology/development 347
            abnormal basophil morphology 108
              abnormal basophil cell number + 108
Path 2
Term Annotations click to browse term
  mammalian phenotype 16476
    hematopoietic system phenotype 5344
      abnormal hematopoietic system morphology/development 4885
        abnormal hematopoietic cell morphology 4062
          abnormal leukocyte morphology 2710
            abnormal myeloid leukocyte morphology 1397
              abnormal granulocyte morphology 884
                abnormal basophil morphology 108
                  abnormal basophil cell number + 108
paths to the root