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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to infection
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Accession:MP:0002406 term browser browse the term
Definition:greater likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens
Synonyms:exact_synonym: decreased resistance to infection
 broad_synonym: susceptibility to infection
 alt_id: MP:0002550;   MP:0003001



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increased susceptibility to viral infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnar1 interferon alpha and beta receptor subunit 1 IMP RGD PMID:27999109 RGD:12910492 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979
JBrowse link
G Ifnar1em1 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1 IMP RGD PMID:27999109 RGD:12910492
G Ifnar1em2 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 2 IMP RGD PMID:27999109 RGD:12910492

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5421
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal response to antigen 28
          abnormal response to infection 28
            abnormal susceptibility to infection 28
              increased susceptibility to infection 16
                increased susceptibility to bacterial infection + 0
                increased susceptibility to fungal infection 0
                increased susceptibility to infection induced morbidity/mortality + 8
                increased susceptibility to parasitic infection + 7
                increased susceptibility to prion infection 0
                increased susceptibility to viral infection + 9
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