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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal lung interstitium morphology
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Accession:MP:0002276 term browser browse the term
Definition:any structural anomaly of the connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin; it functions in the mechanical behavior of the lung, and forms a barrier to regulate the flow of plasma constituents from the capillaries to the airway and alveolar spaces
Synonyms:exact_synonym: abnormal pulmonary interstitium morphology;   lung interstitium dysplasia



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S WAG/RijCmcr MODEL: induced IAGP whole thorax irradiation RGD PMID:18470747 RGD:2303635

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  mammalian phenotype 5402
    respiratory system phenotype 47
      abnormal respiratory system morphology 33
        abnormal lung morphology 26
          abnormal lung interstitium morphology 1
            pulmonary interstitial fibrosis 1
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