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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal skeleton development
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Accession:MP:0002113 term browser browse the term
Definition:any anomaly in the formation of bone tissue
Synonyms:exact_synonym: abnormal bone development;   abnormal bone formation/ structure;   abnormal skeletogenesis;   skeletal: osteogenesis/developmental anomalies
 alt_id: MP:0000056;   MP:0001534;   MP:0001537
 xref: MGI:2173561


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abnormal epiphyseal plate morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IMP RGD PMID:29190650 RGD:151347176 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cftrem1Sage cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage IMP RGD PMID:29190650 RGD:151347176
abnormal long bone hypertrophic chondrocyte zone term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkg2 protein kinase cGMP-dependent 2 IAGP DNA:deletion:cds (rat) RGD PMID:15466490 RGD:150429792 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
abnormal ossification involved in bone maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb16 zinc finger and BTB domain containing 16 IAGP RGD PMID:27727328 RGD:40924666 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
chondrodystrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain IDA RGD PMID:10853827 RGD:704421 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
decreased width of hypertrophic chondrocyte zone term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppc natriuretic peptide C IMP compared to wild type RGD PMID:29566041 RGD:127284867 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Nppcem3Kyo natriuretic peptide C; ZFN induced mutant 3, Kyo IMP compared to wild type RGD PMID:29566041 RGD:127284867
G Nppcem4Kyo natriuretic peptide C; ZFN induced mutant 4, Kyo IMP compared to wild type RGD PMID:29566041 RGD:127284867
increased long bone epiphyseal plate size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkg2 protein kinase cGMP-dependent 2 IAGP DNA:deletion:cds (rat) RGD PMID:15466490 RGD:150429792 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5372
    skeleton phenotype 434
      abnormal skeleton morphology 339
        abnormal skeleton development 13
          abnormal cartilage development + 7
          abnormal chondrocyte differentiation + 0
          abnormal epiphyseal plate morphology + 10
          abnormal fontanelle morphology + 0
          abnormal long bone epiphysis morphology + 0
          abnormal ossification involved in bone maturation + 1
          abnormal osteoblast differentiation + 0
          abnormal osteoclast differentiation 0
          abnormal osteoid morphology + 0
          abnormal rib development 1
          abnormal sclerotome morphology + 0
          abnormal vertebrae development + 1
          chondrodystrophy 1
paths to the root