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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal consumption behavior
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Accession:MP:0002069 term browser browse the term
Definition:altered ability or inability to eat or drink, or unusual choice or avoidance of foods or drink
Synonyms:exact_synonym: abnormal consumption behaviour;   abnormal eating/drinking behavior;   abnormal eating/drinking behaviour;   abnormal feeding/drinking behavior;   abnormal feeding/drinking behaviour;   neurological/behavioral: feeding/drinking anomalies;   neurological/behavioural: feeding/drinking anomalies
 xref: MGI:2173574


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abnormal drinking behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP RGD PMID:14568317 RGD:1626460 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422 		JBrowse link
abnormal food preference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mc4r melanocortin 4 receptor IMP RGD PMID:21527895 RGD:6478803 NCBI chr18:62,689,798...62,691,685 JBrowse link
alcohol aversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP RGD PMID:11535626 RGD:15036815 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
alcohol preference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 IAGP DNA:polymorphism RGD PMID:11825850 RGD:2306323 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IAGP DNA:polymorphism RGD PMID:15900217 RGD:2306341 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Arrb2 arrestin, beta 2 IAGP RGD PMID:18367649 RGD:401938607 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IAGP DNA:polymorphism, missense mutation:promoter, cds RGD PMID:24611993 RGD:8662401 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:85,554,268...85,596,318 		JBrowse link
G Faah fatty acid amide hydrolase treatment IMP RGD PMID:29071769 RGD:408361844 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 IAGP DNA:polymorphism:CDS:amino acid R100Q, Q allele higher in the alcohol preferring ANA line than the AA non-preferring line (P<0.0001) RGD PMID:14615016 RGD:1626511 NCBI chr10:27,311,965...27,327,337
Ensembl chr10:27,311,979...27,327,234 		JBrowse link
G Npy neuropeptide Y IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Npyem6Sage neuropeptide Y; zinc finger nuclease induced mutant 6, Sigma Advanced Genetic Engineering Labs IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013
G Pnoc prepronociceptin treatment IMP RGD PMID:12818717 RGD:616363155 NCBI chr15:43,800,240...43,827,841
Ensembl chr15:43,800,246...43,827,470 		JBrowse link
decreased food intake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 IMP compared to wild type RGD PMID:32306766 RGD:155598602 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739 		JBrowse link
G Bmal1em1Mcwi basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi IMP compared to wild type RGD PMID:32306766 RGD:155598602
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP compared to wild type RGD PMID:35328827 RGD:405100966 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:152,284,841...152,322,675 		JBrowse link
G Fmr1em1Sage FMRP translational regulator 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP compared to wild type RGD PMID:35328827 RGD:405100966
G Ghsr growth hormone secretagogue receptor IMP compared to wild type rats in response to ghrelin (CHEBI:75431)
DNA:missense mutation:cds:nucleotide 1027 		RGD PMID:12045256 PMID:21258824 PMID:27129673 PMID:29453460 RGD:625699, RGD:150520012, RGD:150520013, RGD:13825258 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:112,196,767...112,201,181 		JBrowse link
G Ghsrm1Mcwi growth hormone secretagogue receptor; mutation 1, Medical College of Wisconsin IMP compared to wild type rats
compared to wild type rats in response to ghrelin (CHEBI:75431) 		RGD PMID:27129673 PMID:21258824 RGD:150520013, RGD:150520012
G Ghsrem1Ottc growth hormone secretagogue receptor;CRISPR induced mutant 1, Ottc IMP RGD PMID:29453460 RGD:13825258
G Pmch pro-melanin-concentrating hormone IMP RGD PMID:19934402 RGD:150429945 NCBI chr 7:24,399,404...24,400,720
Ensembl chr 7:24,399,404...24,400,720 		JBrowse link
G Pmchm1Hubr pro-melanin-concentrating hormone; ENU induced mutant1, Hubr IMP RGD PMID:19934402 RGD:150429945
increased alcohol consumption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IAGP RGD PMID:16899727 RGD:1600586 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit IMP compared to wild type RGD PMID:31288250 RGD:150530288 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:64,265,879...64,294,233 		JBrowse link
G Chrna5em20(D398N)Pas cholinergic receptor, nicotinic, alpha 5 (neuronal); ZFN induced mutant 20,Pas IMP compared to wild type RGD PMID:31288250 RGD:150530288
G Crhr1 corticotropin releasing hormone receptor 1 IAGP DNA:polymorphism:promoter RGD PMID:17015825 RGD:1626233 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12086672 RGD:1580677 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Npy neuropeptide Y IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:15670655 RGD:1642509 NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:170,200,027...170,210,448 		JBrowse link
G Npyem6Sage neuropeptide Y; zinc finger nuclease induced mutant 6, Sigma Advanced Genetic Engineering Labs IAGP as compared to NP/Iusm; RGD PMID:27461754 RGD:11530013
increased fluid intake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insr insulin receptor induced IMP RGD PMID:19017805 RGD:2314405 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
G Lepr leptin receptor IAGP DNA:mutations::cds: : (rat) RGD PMID:10901178 RGD:401965414 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Mc4r melanocortin 4 receptor IMP RGD PMID:21527895 PMID:24400148 RGD:6478803, RGD:13825242 NCBI chr18:62,689,798...62,691,685 JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:21527895 PMID:24400148 RGD:6478803, RGD:13825242
G Sod3 superoxide dismutase 3 IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
increased food intake term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IAGP compared to age-matched lean heterozygous +/fa rats RGD PMID:9843879 RGD:628910 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Leprfa leptin receptor; fa mutant IAGP compared to age-matched lean heterozygous +/fa rats RGD PMID:9843879 RGD:628910
G Sod3 superoxide dismutase 3 IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sod3m1Mcwi superoxide dismutase 3; mutation 1, Medical College of Wisconsin IMP compared to SS/JrHsdMcwi RGD PMID:31972339 RGD:150573712
low alcohol preference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:30456835 RGD:13825259 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:112,196,767...112,201,181 		JBrowse link
G Ghsrem1Ottc growth hormone secretagogue receptor;CRISPR induced mutant 1, Ottc IMP RGD PMID:30456835 RGD:13825259
polydipsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:35695380 RGD:155630629 NCBI chr10:58,300,069...58,315,725
Ensembl chr10:58,299,967...58,321,661 		JBrowse link
polyphagia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cckar cholecystokinin A receptor IAGP RGD PMID:9530226 RGD:7257724 NCBI chr14:61,505,270...61,513,618
Ensembl chr14:61,505,270...61,513,618 		JBrowse link
G Lepr leptin receptor IAGP RGD PMID:23154293 RGD:13432147 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Leprfa leptin receptor; fa mutant IAGP RGD PMID:23154293 RGD:13432147
G Mc4r melanocortin 4 receptor IMP RGD PMID:21527895 PMID:24400148 RGD:6478803, RGD:13825242 NCBI chr18:62,689,798...62,691,685 JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:21527895 PMID:24400148 RGD:6478803, RGD:13825242
G Prlhr prolactin releasing hormone receptor IAGP RGD PMID:15854142 RGD:1641829 NCBI chr 1:269,592,735...269,594,422
Ensembl chr 1:269,585,611...269,594,909 		JBrowse link
saccharin preference term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh13 cadherin 13 IMP knock-out compared to wild-type rats RGD PMID:28387990 RGD:13503340 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119 		JBrowse link
G Cdh13em1Mcwi cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP knock-out compared to wild-type rats RGD PMID:28387990 RGD:13503340
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5432
    behavior/neurological phenotype 622
      abnormal behavior 621
        abnormal consumption behavior 200
          abnormal drinking behavior + 128
          abnormal eating behavior + 86
paths to the root