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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal associative learning
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Accession:MP:0002062 term browser browse the term
Definition:anomaly in the ability to change the frequency or form of a behavior as a result of the influence of the environment
Synonyms:exact_synonym: abnormal conditioning behavior;   abnormal conditioning behaviour;   neurological/behavioral: conditioning defect;   neurological/behavioural: conditioning defect
 xref: MGI:2173567



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abnormal conditioned emotional response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IDA decreased after administration of D2 antagonist RGD PMID:11311883 RGD:1581463 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
abnormal conditioned place aversion behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twf1 twinfilin actin-binding protein 1 IMP RGD PMID:33963280 RGD:596938166 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:125,716,015...125,727,894
JBrowse link
abnormal conditioned taste aversion behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcz protein kinase C, zeta IDA inhibition eliminates long term memory of taste aversion stimulus RGD PMID:17702943 RGD:1642657 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
abnormal cued conditioning behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IMP RGD PMID:19160503 RGD:529195970 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
abnormal operant conditioning behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP DNA:deletion:intron 7, exon 8: RGD PMID:30877790 RGD:38548928 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fmr1em1Sage FMRP translational regulator 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP DNA:deletion:intron 7, exon 8: RGD PMID:30877790 RGD:38548928
G Shank2 SH3 and multiple ankyrin repeat domains 2 IMP RGD PMID:29970986 RGD:126790534 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
JBrowse link
G Shank2em13Sage SH3 and multiple ankyrin repeat domains 2; ZFN induced mutant13, Sage IMP RGD PMID:29970986 RGD:126790534
abnormal passive avoidance behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IAGP RGD PMID:14568317 RGD:1626460 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Kdr kinase insert domain receptor IDA RGD PMID:15258583 RGD:1581594 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018
JBrowse link
enhanced conditioned place preference behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:21095077 RGD:14348962 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oprl1m1Hubr opioid related nociceptin receptor 1; ENU induced mutant1, Hubr IMP RGD PMID:21095077 RGD:14348962
G Slc6a4 solute carrier family 6 member 4 IMP compared to wild type littermate RGD PMID:18581099 RGD:4889490 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slc6a4m1Hubr solute carrier family 6 member 4; ZFN induced mutant1, Hubr IMP compared to wild type littermate RGD PMID:18581099 RGD:4889490
enhanced cued conditioning behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 sexual_dimorphism IMP associated with abnormal freezing behavior (MP:0020420); compared to female wild type littermate RGD PMID:31329100 RGD:407571699 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr3c1em1Kuan nuclear receptor subfamily 3, group C, member 1; CRISPR/Cas9 induced mutant1, Kuan sexual_dimorphism IMP associated with abnormal freezing behavior (MP:0020420); compared to female wild type littermate RGD PMID:31329100 RGD:407571699
impaired conditioned place preference behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IMP compared to WT RGD PMID:23583595 RGD:38501054 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bdnfem1Sage brain-derived neurotrophic factor; ZFN induced mutant 1, Sage IMP compared to WT RGD PMID:23583595 RGD:38501054
impaired conditioned taste aversion behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor sexual_dimorphism IMP RGD PMID:30769105 RGD:407419883 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrem2Sage aryl hydrocarbon receptor; ZFN induced mutant2, Sage sexual_dimorphism IMP RGD PMID:30769105 RGD:407419883
impaired cued conditioning behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrg1 neuregulin 1 IMP RGD PMID:23022220 RGD:39128254 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrg1Tn(sb-T2/Bart3)2.183Mcwi neuregulin 1; transposon insertion 2.183, Medical College of Wisconsin IMP RGD PMID:23022220 RGD:39128254

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5421
    behavior/neurological phenotype 614
      abnormal behavior 613
        abnormal cognition 127
          abnormal learning/memory/conditioning 124
            abnormal associative learning 41
              abnormal avoidance learning behavior + 18
              abnormal cocaine conditioned locomotor activation 0
              abnormal conditioned emotional response 1
              abnormal conditioned place preference behavior + 9
              abnormal contextual conditioning behavior + 0
              abnormal cued conditioning behavior + 7
              abnormal eye blink conditioning behavior 0
              abnormal latent inhibition of conditioning behavior 0
              abnormal operant conditioning behavior 6
paths to the root