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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal gametogenesis
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Accession:MP:0001929 term browser browse the term
Definition:defective formation or differentiation of germ cells


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abnormal meiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spata22 spermatogenesis associated 22 treatment IDA RGD PMID:23903057 RGD:38549346 NCBI chr10:58,443,736...58,461,578
Ensembl chr10:58,417,415...58,461,908 		JBrowse link
abnormal spermatogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated IAGP
IMP 		RGD PMID:16964288 PMID:16964288 RGD:1599505, RGD:1599505 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194 		JBrowse link
G Brca2m1Uwm BRCA2, DNA repair associated; mutation 1, University of Wisconsin-Madison IMP RGD PMID:16964288 RGD:1599505
G Dnd1 DND microRNA-mediated repression inhibitor 1 IAGP compared to WKY RGD PMID:22655094 RGD:40924659 NCBI chr18:28,652,712...28,655,336
Ensembl chr18:28,652,712...28,655,336 		JBrowse link
G Dnd1ter DND microRNA-mediated repression inhibitor 1, ter mutant IAGP compared to WKY RGD PMID:22655094 RGD:40924659
absent germ cells term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnd1 DND microRNA-mediated repression inhibitor 1 IAGP compared to WKY RGD PMID:22655094 RGD:40924659 NCBI chr18:28,652,712...28,655,336
Ensembl chr18:28,652,712...28,655,336 		JBrowse link
G Dnd1ter DND microRNA-mediated repression inhibitor 1, ter mutant IAGP compared to WKY RGD PMID:22655094 RGD:40924659
absent oocytes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 IMP compared to wild type RGD PMID:28520870 RGD:38548924 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Esr2em1Soar estrogen receptor 2; ZFN induced mutant 1, Soar IMP compared to wild type RGD PMID:28520870 RGD:38548924
arrest of spermiogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sbf1 SET binding factor 1 IAGP DNA:substitution:intron 37:G>A (rat) RGD PMID:27335132 RGD:38549340 NCBI chr 7:122,237,968...122,264,591
Ensembl chr 7:122,237,968...122,264,531 		JBrowse link
G Sbf1m1Ipcv SET binding factor 1; mutation 1, Institute of Physiology, Czechoslovac Academy of Sciences IAGP RGD PMID:27335132 RGD:38549340
G Spata22 spermatogenesis associated 22 treatment IDA RGD PMID:23903057 RGD:38549346 NCBI chr10:58,443,736...58,461,578
Ensembl chr10:58,417,415...58,461,908 		JBrowse link
azoospermia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sbf1 SET binding factor 1 IAGP DNA:substitution:intron 37:G>A (rat) RGD PMID:27335132 RGD:38549340 NCBI chr 7:122,237,968...122,264,591
Ensembl chr 7:122,237,968...122,264,531 		JBrowse link
G Sbf1m1Ipcv SET binding factor 1; mutation 1, Institute of Physiology, Czechoslovac Academy of Sciences IAGP RGD PMID:27335132 RGD:38549340
impaired sperm capacitation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Defb23em2MlitDefb26em2Mlit defensin beta 23, defensin beta 26; CRISPR/Cas9 induced mutant2, Mlit IMP RGD PMID:29141997 RGD:13782190
short sperm flagellum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem67 transmembrane protein 67 IAGP RGD PMID:19515853 RGD:8554306 NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:30,333,793...30,386,666 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5440
    reproductive system phenotype 129
      abnormal reproductive system morphology 97
        abnormal gametogenesis 20
          abnormal DNA methylation during gametogenesis 0
          abnormal germ cell morphology + 11
          abnormal meiosis + 2
          abnormal oogenesis + 4
          abnormal sperm number + 3
          abnormal spermatogenesis + 16
          transmission ratio distortion 0
paths to the root