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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased dopamine level
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Accession:MP:0001906 term browser browse the term
Definition:greater than the normal amount of dopamine, a catecholamine neurotransmitter and neurohormone that is derived from tyrosine and is the precursor to norepinephrine and epinephrine; it functions as a neurotransmitter in the brain and as a hormone to inhibit the release of prolactin from the anterior lobe of the pituitary
Synonyms:exact_synonym: increased dopaminergic levels


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increased dopamine level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrl3 adhesion G protein-coupled receptor L3 IAGP MGI PMID:22575564 NCBI chr 5:81,167,600...81,980,556
Ensembl chr 5:81,167,985...81,972,980 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide IAGP MGI PMID:21075145 NCBI chr 3:137,903,828...137,937,803
Ensembl chr 3:137,923,521...137,939,143 		JBrowse link
G Aqp4 aquaporin 4 IAGP MGI PMID:16797122 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 IAGP MGI PMID:29456827 NCBI chr 8:14,956,405...15,051,085
Ensembl chr 8:14,961,663...15,051,085 		JBrowse link
G Cd81 CD81 antigen IAGP MGI PMID:11376857 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS IAGP MGI PMID:11752469 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 IAGP MGI PMID:20147565 NCBI chr 2:91,752,534...91,760,180
Ensembl chr 2:91,757,594...91,759,033 		JBrowse link
G Cntnap4 contactin associated protein-like 4 IAGP MGI PMID:24870235 NCBI chr 8:113,296,523...113,609,339
Ensembl chr 8:113,296,675...113,609,349 		JBrowse link
G Comt catechol-O-methyltransferase IAGP MGI PMID:9707588 PMID:19930170 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
G Dbh dopamine beta hydroxylase IAGP MGI PMID:7715704 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212 		JBrowse link
G Drd2 dopamine receptor D2 IAGP MGI PMID:22745501 NCBI chr 9:49,251,633...49,319,477
Ensembl chr 9:49,251,927...49,319,477 		JBrowse link
G Drd4 dopamine receptor D4 IAGP MGI PMID:9323127 NCBI chr 7:140,871,887...140,876,377
Ensembl chr 7:140,871,919...140,876,377 		JBrowse link
G En1 engrailed 1 IAGP MGI PMID:12764108 PMID:22745501 NCBI chr 1:120,530,216...120,535,720
Ensembl chr 1:120,530,147...120,535,721 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 (zygin I) IAGP MGI PMID:18647754 NCBI chr 9:36,732,694...36,790,222
Ensembl chr 9:36,733,160...36,790,220 		JBrowse link
G Foxp2 forkhead box P2 IAGP MGI PMID:19490899 NCBI chr 6:14,901,348...15,441,976
Ensembl chr 6:14,901,348...15,441,976 		JBrowse link
G Fyn Fyn proto-oncogene IAGP MGI PMID:11834300 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377 		JBrowse link
G Gpx1 glutathione peroxidase 1 IAGP MGI PMID:24075852 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Grm2 glutamate receptor, metabotropic 2 IAGP MGI PMID:15753323 NCBI chr 9:106,521,733...106,533,308
Ensembl chr 9:106,520,294...106,533,281 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 IAGP MGI PMID:20178820 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Hdc histidine decarboxylase IAGP MGI PMID:24411733 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219 		JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A IAGP MGI PMID:11080193 NCBI chr13:105,580,201...105,584,641
Ensembl chr13:105,580,147...105,584,630 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IAGP MGI PMID:14697676 NCBI chr 4:58,435,252...58,554,601
Ensembl chr 4:58,435,255...58,553,898 		JBrowse link
G Maf1 MAF1 homolog, negative regulator of RNA polymerase III IAGP MGI PMID:25934505 NCBI chr15:76,235,494...76,238,578
Ensembl chr15:76,235,494...76,238,580 		JBrowse link
G Maoa monoamine oxidase A IAGP MGI PMID:7792602 PMID:15272015 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Maob monoamine oxidase B IAGP MGI PMID:15272015 NCBI chr  X:16,575,520...16,683,605
Ensembl chr  X:16,575,521...16,683,605 		JBrowse link
G Oprl1 opioid receptor-like 1 IAGP MGI PMID:15030410 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778 		JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 IAGP MGI PMID:15799973 PMID:24075852 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) IAGP MGI PMID:9832165 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:10470087 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IAGP MGI PMID:12915482 PMID:12930822 PMID:17116640 PMID:18691389 PMID:24075852 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:19750226 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) IAGP MGI PMID:20092576 NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase IAGP MGI PMID:21178975 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 IAGP MGI PMID:20551902 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065 		JBrowse link
G Shh sonic hedgehog IAGP MGI PMID:22841315 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 IAGP MGI PMID:23580201 NCBI chr 8:93,687,100...93,728,295
Ensembl chr 8:93,686,707...93,728,295 		JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 IAGP MGI PMID:11172062 PMID:16754872 PMID:16950153 PMID:19750226 PMID:22841315 More... NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791 		JBrowse link
G Snca synuclein, alpha IAGP MGI PMID:24082145 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839 		JBrowse link
G Taar1 trace amine-associated receptor 1 IAGP MGI PMID:17212650 PMID:22114263 NCBI chr10:23,796,304...23,797,302
Ensembl chr10:23,796,254...23,797,367 		JBrowse link
G Ube3a ubiquitin protein ligase E3A IAGP MGI PMID:22916201 NCBI chr 7:58,871,891...58,960,585
Ensembl chr 7:58,878,498...58,961,284 		JBrowse link
G Vav2 vav 2 oncogene IAGP MGI PMID:17202406 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045 		JBrowse link
G Vav3 vav 3 oncogene IAGP MGI PMID:16767097 PMID:17202406 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014 		JBrowse link
increased nervous system dopamine level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdnf cerebral dopamine neurotrophic factor IAGP MGI PMID:31783118 NCBI chr 2:3,514,102...3,527,413
Ensembl chr 2:3,514,067...3,527,413 		JBrowse link
G Gpr88 G-protein coupled receptor 88 IAGP MGI PMID:26188600 NCBI chr 3:116,043,303...116,047,229
Ensembl chr 3:116,043,303...116,047,152 		JBrowse link
G Miat myocardial infarction associated transcript (non-protein coding) IAGP MGI PMID:27251103 NCBI chr 5:112,361,094...112,376,814
Ensembl chr 5:112,361,094...112,377,261 		JBrowse link
increased urine dopamine level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus IAGP MGI PMID:10712433 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16239
    homeostasis/metabolism phenotype 7359
      abnormal homeostasis 6528
        abnormal catecholamine level 174
          abnormal dopamine level 119
            increased dopamine level 46
              increased circulating dopamine level 0
              increased nervous system dopamine level 3
              increased urine dopamine level 1
paths to the root